Provided is a microfluidic device that, as compared with a conventional microfluidic device, (i) is smoother in surface of a water-repellent layer provided above a segment electrode and (ii) makes it easier for microfluid provided in the surface of the water-repellent layer to slide. A microfluidic device (1) includes: an array substrate (10) including a plurality of electrodes (14); and a counter substrate (40) including at least one electrode (42), the array substrate (10) and the counter substrate (40) having therebetween an internal space (50) in which to cause an electroconductive droplet (51) to move across the plurality of electrodes (14), and the plurality of electrodes (14) being provided on a first flattening resin layer (13) and each being a light-blocking metal electrode.

A secure assay device is disclosed herein that provides: an assay or a test device that provides at least one result, wherein the assay or test device comprises at least one surface which exhibits optical change in response to at least one target particle, at least one marker or a combination thereof; and at least one multi-layer coating that at least partially covers the assay membrane, the assay device or a combination thereof, wherein the multi-layer coating blocks or impairs the user visualization of the optical change, the at least one result or a combination thereof. A secure reader and method of utilizing the secure assay device and secure reader are disclosed herein.

Disclosed are methods and apparatus for solar-thermal microfluidic polymerase chain reaction. A device comprises a microfluidic chip including at least one PCR region, an energy absorption layer disposed adjacent to the microfluidic chip, a solar energy concentrator adapted to produce a plurality of temperature profiles on the microfluidic chip adapted to facilitate PCR, and a photomask disposed between the solar energy concentrator and the microfluidic chip.

An evacuated container assembly suitable for use in connection with blood collection including: (a) a container member formed of a first polymeric material and having a sidewall and one or more openings; (b) a nanocomposite barrier coating disposed on the container member having a thickness of up to about 30 microns and being derived from an aqueous dispersion including (i) a dispersed barrier matrix polymer; and (ii) a substantially exfoliated silicate filler having an aspect ratio of more than 50; and (c) one or more sealing members disposed in the opening(s) operative to hermetically seal the cavity; wherein the cavity is evacuated and maintains a pressure below atmospheric pressure and exhibits a draw volume loss lower than that of a like assembly without a nanocomposite barrier film by a factor of at least 1.5.

A reinforced microplate has reinforcing members that enhance stiffness and minimize deformation of the microplate, especially thermally-induced deformation. The reinforcing members include ribs or struts that are integrally formed on a bottom surface of the microplate. In cooperation with the reinforcing members, the microplate frame can include one or more slots that act to disrupt the effects of thermal expansion and limit thermally-induced strain.

A fluidic system that includes a reagent manifold comprising a plurality of channels configured for fluid communication between a reagent cartridge and an inlet of a flow cell; a plurality of reagent sippers extending downward from ports in the manifold, each of the reagent sippers configured to be placed into a reagent reservoir in a reagent cartridge so that liquid reagent can be drawn from the reagent reservoir into the sipper; at least one valve configured to mediate fluid communication between the reservoirs and the inlet of the flow cell. The reagent manifold can also include cache reservoirs for reagent re-use.

Diagnostic devices; systems, methods and computer-readable media store instructions related to determining hemoglobin information using those devices. The methods may include processing a captured image of the reservoir and/or device and the device information to determine color information for the solution and the scale, the color information including one or more color attributes; adjusting the color information for the solution based on the color information for the scale; and determining hemoglobin information (e.g., hemoglobin level, disease state and/or calculated hematocrit) based on the adjusted color information and a stored profile information associated with the device information.

[Problem to be solved] A sample storage tube having the seal function to the tube body is provided by integral molding and the airtightness is secured in the sample storage tube.

[Solution] The sample storage tube 100 comprise a first molded portion 210 and a second molded portion 220 by the integral molding. The first molded portion 210 is molded as the base figure of the tube body. The second molded portion 220 includes at least the opening edge portion which contacts the lid 300 and closes the opening. The first molded portion 210 is molded by the first material such as polypropylene, the second molded portion 220 is molded by the second material such as TPE which is suitable for the seal object to secure the airtightness between the opening and the lid 300. This second molded portion providing the seal function is molded onto the opening edge of the tube body by the integral molding. The second molded portion 220 can be molded as a consecutive object from the bottom portion to the opening edge of the tube body.

Under one aspect, a device is provided for use in luminescent imaging. The device can include a photonic superlattice including a first material, the first material having a first refractive index. The first material can include first and second major surfaces and first and second pluralities of features defined though at least one of the first and second major surfaces, the features of the first plurality differing in at least one characteristic from the features of the second plurality. The photonic superlattice can support propagation of a first wavelength and a second wavelength approximately at a first angle out of the photonic superlattice, the first and second wavelengths being separated from one another by a first non-propagating wavelength that does not selectively propagate at the first angle out of the photonic superlattice. The device further can include a second material having a second refractive index that is different than the first refractive index. The second material can be disposed within, between, or over the first and second pluralities of features and can include first and second luminophores. The device further can include a first optical component disposed over one of the first and second major surfaces of the first material. The first optical component can receive luminescence emitted by the first luminophore at the first wavelength approximately at the first angle, and can receive luminescence emitted by the second luminophore at the second wavelength approximately at the first angle.

The invention relates to thermal cycling device comprising: a sample location; a first heating means, wherein advantageously said first heating means is a contact heating means; a second heating means, wherein said second heating means is configured to bring said sample to a second temperature by directing electromagnetic radiation to the first light pipe section end and the light pipe section is configured to direct said electromagnetic radiation through its second end to the sample location, its uses and methods based thereon.