B01L2300/168

Microfluidic rotor device

Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer to collectively define a set of wells. The second layer may define a channel, and the second layer may be substantially absorbent to infrared radiation. A third layer may be coupled to the second layer. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.

Systems and methods for manufacturing a microfluidic rotor device

Described herein are various embodiments directed to rotor devices, methods, and systems. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include bonding a first layer and a second layer using two-shot injection molding. The first layer coupled to the second layer may collectively define a set of wells. The first layer may be substantially transparent. The second layer may define a channel. The second layer may be substantially absorbent to infrared radiation. A third layer may be bonded to the second layer using infrared radiation. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.

THERMOCYCLING SYSTEM, COMPOSITION, AND MICROFABRICATION METHOD

A system and method of manufacture for the system, comprising a set of heater-sensor dies, each heater-sensor die comprising an assembly including a first insulating layer, a heating region comprising an adhesion material layer coupled to the first insulating layer and a noble material layer, and a second insulating layer coupled to the heating region and to the first insulating layer through a pattern of voids in the heating region, wherein the pattern of voids in heating region defines a coarse pattern associated with a heating element of the heating region and a fine pattern, integrated into the coarse pattern and associated with a sensing element of the heating region; an electronics substrate configured to couple heating elements and sensing elements of the set of heater-sensor dies to a controller; and a set of elastic elements configured to bias each of the set of heater-sensor dies against a detection chamber.

PIPETTE TIP CARRIER ASSEMBLY

A pipette tip carrier assembly suitable for storing elongate pipette tips in a biochemical analyser is described. The pipette tip carrier assembly comprises one or more holding elements each adapted to hold, in use, a respective pipette tip oriented such that the elongate dimension of the held pipette tip is parallel to a first axis. The pipette tip carrier assembly also includes a light source arranged to produce, at a position distal to the one or more holding elements along the first axis, light directed towards each of the one or more holding elements so as to be intercepted by one or more pipette tips held in 10 use by the one or more holding elements.

MICROPLATE ASSEMBLY AND METHOD FOR TRANSFERRING SAMPLE BY MEANS OF A MICROPLATE ASSEMBLY
20220195363 · 2022-06-23 ·

A microplate assembly for a plurality of samples includes a donor microplate having a plurality of sample donor cavities. The microplate assembly further includes a receiver microplate having a plurality of sample receiver cavities each sample receiver cavity having a transparent receiver bottom configured to enable microscopic imaging. In addition, the microplate assembly includes a leak-tight connecting structure configured to assemble the donor microplate and the receiver microplate, with at least one of the sample donor cavities being in communication with at least one of the sample receiver cavities. Further aspects are a receiver microplate and a leak-tight connecting structure for a microplate assembly as well as a method for transferring samples by means of a microplate assembly.

LABORATORY ANALYZER
20220197578 · 2022-06-23 · ·

A laboratory analyzer is disclosed. The laboratory analyzer comprises a housing at least partially enclosing at least one analyzing instrument and at least one display device, wherein the display device comprises at least one screen, wherein the screen is partially transparent and reflective, wherein the screen is integrated into the housing, wherein the display device is configured for displaying screen information on the screen such that the screen information is visible and/or readable from outside the housing.

Microfluidic Device Unit
20220193674 · 2022-06-23 ·

A microfluidic device unit is provided. The microfluidic device unit includes: (a) a unit inlet and a unit outlet; (b) a cavity including a fluidic channel; (c) a fluidic resistor; and (d) a filter, wherein the unit inlet, the unit outlet, the fluidic channel, and the fluidic resistor are fluidically coupled to one another, wherein the cavity, the fluidic resistor, and the filter are between the unit inlet and the unit outlet, wherein the cavity is upstream of the fluidic resistor, and wherein the filter is positioned so as to filter fluid after it enters the fluidic channel and before it enters the fluidic resistor. A microfluidic device array comprising the microfluidic device unit, a diagnostic apparatus comprising the microfluidic device array, a process for making the array and a method for using the array for sensing an analyte are also provided.

Thrombelastography device, heating apparatus, blood coagulation analysis system and rotational angle measurement method

A thrombelastography device, a heating apparatus, a blood coagulation analysis system, and a rotational angle measurement method are disclosed. The thrombelastography device consists of a plurality of thrombelastography device splits (2) that are horizontally arranged in parallel. The thrombelastography device split (2) comprises a worktable (4), a rack (5), a test bar (6), a tester (8), and a processor (9). The thrombelastography device overcomes the defect in the prior art that the measurement result of a thrombelastography device is inaccurate. The amount of reflected light is used as a reference for thrombelastographic evaluation, and thus the result is more accurate.

MICROPLATE FOR MICROSCOPY
20220184609 · 2022-06-16 ·

The invention relates to a microplate (10) for microscopy of an organoid (30), comprising: a body (11) having at least one recess (20), the recess (20) being adapted to contain and restrict movement of the organoid (30), and a reflective surface (40), the reflective surface (40) being inclined in relation to the recess (20), such that an incoming beam of light towards the microplate (10) is directed onto the organoid (30) in a substantially horizontal direction.

Method and Apparatus for Rapid Virus Screening and Detection using a Canine
20220187213 · 2022-06-16 ·

A medical swab comprising a thin stick comprising a drawn plastic stick and a sphere-like fiber lump formed on at least one end of the stick. The fibers are chemically treated to enabled a color change when exposed to moisture. On the thin stick, a unique identifier sticker or tab is placed on the swab. A cover is slidably attached and there is a slide stop located near the head or collection area. The cover has an egg shape and split design where the cover is comprised of two equally sized pieces connected by a small hinge portion. The cover has a plurality of holes which allow odor to escape from the cells or material collected on the swab. When in the closed position the clips act as a clasp, which locks the cover in place, creating a cage around the head or sample end.