A solid dosage product having a tailored dissolution profile comprises a carrier block defining a plurality of compartments where each respective compartment is configured to receive one or more active pharmaceutical ingredient and the carrier block being digestible within an animal such that each respective active pharmaceutical ingredient is controllably released; and one or more coating layers applied to the carrier block. A method for manufacturing a solid dosage product having a tailored dissolution comprises manufacturing a digestible carrier block where the carrier block defines a plurality of compartments with each respective compartment configured to receive an active pharmaceutical ingredient; filling a respective compartment with a respective active pharmaceutical ingredient; and coating the carrier block with one or more coating layers.

Embodiments disclosed herein relate to a package comprising a plurality of chambers, each of the plurality of chambers comprising a solid unit dosage comprising an active ingredient, wherein the package is configured to provide an individualized delivery of the active ingredient in different concentrations of the active ingredient to a human or an animal. The effective amount of active ingredient is adjusted in the solid unit dosage according to the size or weight of solid unit dosage. The manufacture of the solid unit dosage comprises mixing of the active substance with pharmaceutically acceptable additives, followed by hot or cold extrusion and spheronization. The solid unit dosages can be manufactured without the use of a tablet press, lyophilization or molding. Solid unit dosages with various drug loads or many drug strengths simultaneously are produced in one batch without further processing.

A continuous skin packaging and coating apparatus and a coating method for tablets. The continuous skin packaging and coating apparatus comprises a lower coating film unreeling roller, a waste edge reeling roller, an upper coating film unreeling roller, a lower coating heating component, an upper coating heating component, a first mold provided with a first table placing hole, a second mold provided with a second tablet placing hole, a heat-sealing plate, a cutting component, a blank tablet implanting component, and an operating mesa. The lower coating film unreeling roller and the waste edge reeling roller are provided on either side of the operating mesa. The lower coating film heating component, the blank tablet implanting component, the upper coating film unreeling roller, the upper coating film heating component, the heat-sealing plate, and the cutting component are sequentially provided above the operating mesa. The first mold is provided under the operating mesa below the blank tablet implanting component. The second mold is provided under the operating mesa below the heat-sealing plate. The upper coating film heating component is provided below the upper coating film unreeling roller.

In an example implementation, a method of producing an ingredient delivery device includes applying a layer of powder within a work space, selectively depositing a liquid active ingredient onto the powder layer where the liquid active ingredient is to function as a fusing agent, and applying fusing energy to the powder layer to control a release profile of the active ingredient upon ingestion of the ingredient delivery device by a user.

A mixing apparatus is configured to efficiently input noodles coated with an additive to a receiving tray, with no need to perform weighing again after the noodles are input to the receiving tray. The mixing apparatus includes at least two hoppers that each house falling noodles and that allows the noodles to fall through rotation of the hoppers. A supply device supplies a sauce to the noodles in the hoppers, and the two hoppers are spaced from one another in the falling direction.

There is described a drum coater including a substantially cylindrical drum having a peripheral drum wall and a predefined diameter, said drum having a substantially horizontal axis of rotation, a top section and a bottom section being defined above and below, respectively, the axis of rotation, said drum being adapted to contain tablets, a coating zone, one or more spray nozzles directed towards the coating zone, and driving means.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

A reactor for forming fully coated particles having a solid core, the reactor comprises a reactor vessel which is configured to receive particles, and a gas phase coating mechanism that is configured to selectively introduce pulses of gas phase materials that form a coating on the particles. The reactor also includes a sieve (16) that is located within the reactor vessel, and a forcing means that is configured to force the particles through the sieve (16) in use. The sieve is configured to deagglomerate any particle aggregates formed in the reactor vessel upon forcing of the particles by the forcing means through the sieve.