A method for delivery of personalized medication or nutrition for an individual is provided. The method includes receiving parameters for the personalized medication at a 3D printer, wherein the parameters comprise one or more ingredients, mixing at least one of the ingredients at the 3D printer, and micro-dispensing the one or more of the ingredients into dose form at the 3D printer.

A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Disclosed are methods and apparatuses for manufacturing a solid formulation for oral administration, comprising an edible substrate portion on which a composition comprising a first pharmaceutical active ingredient is deposited, and solid formulations made thereby. The methods comprise providing an edible substrate in the form of a film comprising a plurality of portions, spraying a liquid formulation comprising the active ingredient and a solvent onto an edible substrate portion and evaporating the solvent to form a solid composition deposited on the edible substrate portion; measuring the quantity of active ingredient supported by the edible substrate portion and comparing to a predetermined value, and dividing the edible substrate into the plurality of portions.

An embodiment of the present invention provides a manufacturing method of an herbal medicinal tablet formulation for treating obesity which is prescribed based on Sasang constitutional medicine, comprises manufacturing a concentrated ephedra powder agent so that an ephedrine content is 3.0-4.0%; determining a weight of the concentrated ephedra powder agent according to each constitution of Sasang constitutional medicine, and manufacturing a side effect-preventing powder agent for each constitution to prevent and suppress side effects according to constitution of Sasang constitutional medicine with respect to the weight of the concentrated ephedra powder agent; mixing the concentrated ephedra powder agent and the side effect-preventing powder agent with a variance of a weight ratio therebetween in consideration of weight, obesity, constitution of Sasang constitutional medicine, and side effects; and tableting the mixture of the prepared ephedra powder agent and side effect-preventing powder agent.

An embodiment of the present invention provides a manufacturing method of an herbal medicinal tablet formulation for treating obesity which is prescribed based on Sasang constitutional medicine, comprises manufacturing a concentrated ephedra powder agent so that an ephedrine content is 3.0-4.0%; determining a weight of the concentrated ephedra powder agent according to each constitution of Sasang constitutional medicine, and manufacturing a side effect-preventing powder agent for each constitution to prevent and suppress side effects according to constitution of Sasang constitutional medicine with respect to the weight of the concentrated ephedra powder agent; mixing the concentrated ephedra powder agent and the side effect-preventing powder agent with a variance of a weight ratio therebetween in consideration of weight, obesity, constitution of Sasang constitutional medicine, and side effects; and tableting the mixture of the prepared ephedra powder agent and side effect-preventing powder agent.

This invention relates to dosage forms for the delivery of drugs across the oral mucosa having improved transmucosal permeability. More specifically, the invention relates to an oral transmucosal dosage form comprising a primary vehicle comprising a crystallization inhibition agent (CIA) system and a drug, and a secondary vehicle. It also relates to methods of designing and making this dosage form, methods of administering this dosage form and methods of packaging the dosage forms.

This invention relates to dosage forms for the delivery of drugs across the oral mucosa having improved transmucosal permeability. More specifically, the invention relates to an oral transmucosal dosage form comprising a primary vehicle comprising a crystallization inhibition agent (CIA) system and a drug, and a secondary vehicle. It also relates to methods of designing and making this dosage form, methods of administering this dosage form and methods of packaging the dosage forms.

A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention, in accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product.

A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention, in accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product.