Methods, assays, compositions and kits for the ligation of short polynucleotides are presented herein. The short polynucleotides are optionally no more than 7 nucleotides in length, and can be as short as 3 or 4 nucleotides in length. The ligation is optionally performed by CV ligase.

Apparatus, systems, methods and articles are described to prepare and track medications and medication containers as they are prepared, administered to patients and, in some cases, disposed of. Information such as medication type, concentration, and volume are associated with medication containers during preparation and this information can later be consumed/utilized when administering the medication from a container to a patient. Disposing of any remaining medication can also be tracked.

A device for delivering a liquid specialty of the pharmaceutical or food supplement type comprises a gelatin reservoir and a cap hermetically closing the reservoir. The device further comprises a tab arranged on the opposite side of the cap with respect to the reservoir, the tab being filled with gelatin.

The present disclosure relates to a drug delivery device, comprising a shell adapted to contain one of a plurality of medicament containers prefilled with different deliverable volumes of a medicament. The shell is transparent at least in an area adapted to contain the medicament container, and a label adapted to be arranged on the shell. The label comprises a foil having a first surface and a second surface, which is adapted to be connected to the shell. At least one cutout or transparent area is arranged in the foil adapted to be placed on the shell such that a medicament container arrangeable or arranged within the shell is visible through the cutout or transparent area. The cutout or transparent area exhibits a size adapted to allow inspection of the deliverable volume of medicament within the medicament container when the label is applied to the shell.

A child-resistant medication container assembly that includes a blister card including a plurality of compartments each configured to support a dosage of medication, and a puck including a body portion, a recess that defines a partition wall in the body portion, and a plurality of openings defined in the partition wall. Each opening corresponds to one of the plurality of compartments in the blister card. The assembly further includes a carton including a first wall opposite a second wall. An access opening is defined in the first wall and a plurality of perforations are defined in the second wall. The access opening is sized to provide access to the plurality of compartments, and each perforation corresponds to one of the plurality of compartments in the blister card.

A container for medication is provided that has an inner sleeve nested within an outer sleeve. The inner sleeve is retained within the outer sleeve by a ring that engages a lip that is located near a top opening of the outer sleeve. Two labels may be attached to the outer sleeve and inner sleeve, respectively. This effective doubles the surface area for printed information compared to conventional containers of a corresponding size.

A method for monitoring the filling of a medication dispenser that comprises a first and a second container for receiving a strip of medication packages. In the method a taking time of the first medication package of the second strip inserted into the second container is compared with a taking time of the last medication package of the first strip inserted into the first container, in order to determine if the delivery of medication packages can be continued after the first strip with the second strip. The invention also relates to a medication dispenser.

A reminder system and methods may be configured for medicine regimen compliance and monitoring. Embodiments may include a control device, a medicine container, a medicine identifier, a medicine container input device, a monitoring device and a portable electrical device. The control device, the medicine container input device and the monitoring device may include microprocessors, memories, input devices and output devices. The control device may provide operations including input and compare, by the microprocessor, a prescription and medicine information. The monitoring device may provide operations including compare, by the microprocessor, the medicine identifier of the medicine container and the medicine information. The monitoring device may also provide operations including determining, by the microprocessor, the amount of medication removed from the medicine container. The operations may further include generate, by the output device, an alert in response to the distance exceeding a threshold.

A medication kit for treating a health condition of a patient is provided. The medication kit includes a plurality of medicinal agents for treating a plurality of symptoms associated with the health condition. Each of the plurality of medicinal agents is adapted to treat one or more symptoms out of the plurality of symptoms. The medication kit further includes a plurality of containers for storing the plurality of medicinal agents. Each container stores one of the plurality of the medicinal agents.

The present invention provides a dispensing container comprising a vessel, the vessel having: a formation and/or discrete element in or on the vessel which causes the centre of gravity of contents of the vessel to be positioned differently, when oriented in a lain-on-side attitude, from its notional position, in the absence of the formation or element in or on the vessel; an additional formation or discrete element in or on the vessel which, when the container is in the lain-on-side attitude, lifts at least a portion of the container away from a surface, wherein, when the container is in the lain-on-side attitude and has a first volume of content, the centre of gravity of the content biases the container to a first orientation, and when the container is in the lain-on-side attitude and has a second volume of content, the centre of gravity of the container biases the container to a second orientation, different to the first.