A61K9/06

NICLOSAMIDE FORMULATIONS AND METHODS OF USE AS CONTRACEPTIVE
20230044449 · 2023-02-09 ·

Disclosed are formulations comprising niclosamide. The formulations disclosed may be used as a unisex and hormone-free on-demand contraceptive.

TOPICAL COMPOSITION COMPRISING TOFACITINIB AND FINGOLIMOD
20230037905 · 2023-02-09 ·

The present disclosure relates to novel topical formulations containing a tofacitinib and or a fingolimod that are useful for treating dermatological conditions, such as atopic dermatitis, psoriasis, and eczema.

INFLAMMATION-RESPONSIVE ANTI-INFLAMMATORY HYDROGELS
20230039279 · 2023-02-09 ·

The present invention relates generally to the field of protease-responsive drug delivery hydrogels, uses thereof, and related methods of their production. More particularly, the invention relates to hydrogels which release anti-inflammatory agents upon reaction with inflammation-related proteases.

INFLAMMATION-RESPONSIVE ANTI-INFLAMMATORY HYDROGELS
20230039279 · 2023-02-09 ·

The present invention relates generally to the field of protease-responsive drug delivery hydrogels, uses thereof, and related methods of their production. More particularly, the invention relates to hydrogels which release anti-inflammatory agents upon reaction with inflammation-related proteases.

USE OF NICOLSAMIDE FORMULATIONS FOR ANTIVIRAL THERAPY
20230040597 · 2023-02-09 ·

Disclosed are niclosamide formulations for use as antiviral therapy. The formulations disclosed herein may be used for treating a sexually-transmitted virus or a respiratory virus (e.g., coronavirus).

USE OF NICOLSAMIDE FORMULATIONS FOR ANTIVIRAL THERAPY
20230040597 · 2023-02-09 ·

Disclosed are niclosamide formulations for use as antiviral therapy. The formulations disclosed herein may be used for treating a sexually-transmitted virus or a respiratory virus (e.g., coronavirus).

Nanoparticles and Nanogel Drug Compositions for Treatment of Age-related Macular Degeneration

Disclosed are nanoparticles and nanogel drug compositions and the use thereof for treating age-related macular degeneration.

Nanoparticles and Nanogel Drug Compositions for Treatment of Age-related Macular Degeneration

Disclosed are nanoparticles and nanogel drug compositions and the use thereof for treating age-related macular degeneration.

GEL COMPOSITIONS, SYSTEMS, AND METHODS

Methods of forming a gel and related methods of treating subjects with such gels are described. The method may include preparing a composition by combining a macromer comprising a first polyethylene glycol (PEG)-based polymer, a poly(ethylenimine)-based polymer, or a poly(1,2-glycerol) carbonate-based polymer, the macromer including at least one first functional moiety, a crosslinking agent comprising a second PEG-based polymer that includes at least one second functional moiety, and a photoinitiator, and activating the photoinitiator via a light source to form the gel.

GEL COMPOSITIONS, SYSTEMS, AND METHODS

Methods of forming a gel and related methods of treating subjects with such gels are described. The method may include preparing a composition by combining a macromer comprising a first polyethylene glycol (PEG)-based polymer, a poly(ethylenimine)-based polymer, or a poly(1,2-glycerol) carbonate-based polymer, the macromer including at least one first functional moiety, a crosslinking agent comprising a second PEG-based polymer that includes at least one second functional moiety, and a photoinitiator, and activating the photoinitiator via a light source to form the gel.