The present invention relates to one or more ligands of a potassium channel β subunit for use in therapy, and in particular for use in treating or preventing a sleep disorder in a subject. The invention also provides a method of screening a test compound to determine if it is a substrate of a potassium channel β subunit.

Compositions contain a therapeutically effective amount of tiglic aldehyde for at least one of provoking the swallowing reflex of dysphagic patients, decreasing appetite by delaying gastric emptying, reducing body weight gain, or reducing glycemia by improving insulin sensitivity improving mood, memory or cognition. Methods are provided that include administering such compositions.

Compositions contain a therapeutically effective amount of tiglic aldehyde for at least one of provoking the swallowing reflex of dysphagic patients, decreasing appetite by delaying gastric emptying, reducing body weight gain, or reducing glycemia by improving insulin sensitivity improving mood, memory or cognition. Methods are provided that include administering such compositions.

Described herein is a method and corresponding composition of matter for inhibiting the growth of fungi and oomycetes. The method includes contacting fungi or oomycetes with a growth inhibitory effective amount of one or more compounds selected from p-hydroxycoumaryl aldehyde, coniferyl aldehyde, and sinapaldehyde, and salts and esters thereof.

Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Agonists for the TRPM-8 receptor, more particularly one or more substances selected from the group of, for example, linalool, geraniol, hydroxycitronellal, WS-3 (N-ethyl-p-menthane-3-carboxamide), WS-23 (2-isopropyl-N,2,3-trimethylbutyramide), Frescolat MAG (1,4-dioxaspiro[4.5]decane-2-methanol), Frescolat ML (menthyl lactate), Coolact P (5-methyl-2-prop-1-en-2-ylcyclohexan-1-ol) and Cooling Agent 10 (menthoxypropanediol), for use as medicaments to counter atopic dermatitis.

Agonists for the TRPM-8 receptor, more particularly one or more substances selected from the group of, for example, linalool, geraniol, hydroxycitronellal, WS-3 (N-ethyl-p-menthane-3-carboxamide), WS-23 (2-isopropyl-N,2,3-trimethylbutyramide), Frescolat MAG (1,4-dioxaspiro[4.5]decane-2-methanol), Frescolat ML (menthyl lactate), Coolact P (5-methyl-2-prop-1-en-2-ylcyclohexan-1-ol) and Cooling Agent 10 (menthoxypropanediol), for use as medicaments to counter atopic dermatitis.

Agonists for the TRPM-8 receptor, more particularly one or more substances selected from the group of, for example, linalool, geraniol, hydroxycitronellal, WS-3 (N-ethyl-p-menthane-3-carboxamide), WS-23 (2-isopropyl-N,2,3-trimethylbutyramide), Frescolat MAG (1,4-dioxaspiro[4.5]decane-2-methanol), Frescolat ML (menthyl lactate), Coolact P (5-methyl-2-prop-1-en-2-ylcyclohexan-1-ol) and Cooling Agent 10 (menthoxypropanediol), for use as medicaments to counter atopic dermatitis.

There is provided an exemplary method of treating weaning piglets to induce weight gain, or to prevent a reduction in rate of weight gain, the method comprising exposing the weaning piglets to a rabbit maternal pheromone having an interomone effect. In an exemplary embodiment, the rabbit maternal pheromone is trans-2-methyl-2-butenal. The method may include the step of applying the rabbit maternal pheromone to a feeder for the weaning piglets. Moreover, the rabbit maternal pheromone may be applied to a feeder (or to the feed) for the weaning piglets at least once during a first week of weaning. Further, the method may include weighing the weaning piglets at intervals to determine a rate of weight gain, and measuring an amount of feed consumed by the weaning piglets to calculate the amount of weight gained per unit of feed consumed.