Patent classifications
A61K2236/30
APPLICATION OF ASARUM TOTAL POLYSACCHARIDES IN PREPARATION OF MEDICINE FOR TREATING COUGH
The present invention discloses an Asarum total polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that the Asarum total polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the total Asarum polysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases.
PHOSPHODIESTERASE 5 INHIBITOR
In one aspect, the present disclosure aims to provide a novel phosphodiesterase 5 inhibitor that uses plants as raw materials. One aspect of the present disclosure relates to a phosphodiesterase 5 inhibitor containing extracts of plants. Another aspect of the present disclosure relates to a food composition, beverage composition, health food, cosmetic, dietary supplement, quasi-drug, or pharmaceutical composition.
PHARMACEUTICAL COMPOSITION COMPRISING GINSENG EXTRACTS FOR PREVENTION AND TREATMENT OF OPHTHALMOLOGICAL DISEASES
Provided is a treatment composition for damage treatment and regeneration promotion of corneal epithelial cells containing gintonin as an active ingredient which is glycolipoprotein or its aggregate isolated from ginseng. Since the gintonin as a drug containing high-concentration LPA has an effect of increasing the concentration of LPA in damaged cornea and inducing the proliferation of corneal epithelial cells to rapidly and significantly restore the damage of the cornea, the composition of the present disclosure can be usefully used as drugs for treatment of corneal erosion and corneal ulcer or equivalent therapeutic agents for corneal injury in humans and animals.
Compositions containing as the active ingredient components from Salvia sclarea seed
The present invention concerns a food supplement comprising Salvia sclarea seeds, or flour, oil or pulp or extracts obtained from the seeds as well as finished food products comprising the food supplement. The present invention further concerns a nutraceutical or cosmetic preparation comprising as an active ingredient Salvia sclarea seeds, or flour, oil or pulp or extracts obtained from the seeds.
Natural formulations
Provided is an all natural composition including naturally-obtained plant extracts.
COMPOSITIONS AND MULTIPLEXED SYSTEMS FOR COUPLED CELL-FREE TRANSCRIPTION-TRANSLATION AND PROTEIN SYNTHESIS AND METHODS FOR USING THEM
In alternative embodiments, provided herein are transcription/translation (TX-TL) systems and methods of using them for use as rapid prototyping platforms for the synthesis, modification and identification of natural products (NPs), and natural product analogs (NPAs) and secondary metabolites, from biosynthetic gene cluster pipelines. In alternative embodiments, exemplary TX-TL systems as provided herein are used for the combinatorial biosynthesis of natural products (NPs), natural product analogs (NPAs) and secondary metabolites. In alternative embodiments, exemplary TX-TL systems as provided herein are used for the rapid prototyping of complex biosynthetic pathways as a way to rapidly assess combinatorial and biosynthetic designs before moving to cellular hosts. In alternative embodiments, these exemplary TX-TL systems are multiplexed for high-throughput (HT) automation and for prototyping engineered platforms for the synthesis or modification of natural products (NPs), and natural product analogs (NPAs) and secondary metabolites analogs.
Method and system for processing whole hemp stalks
A method and system for processing whole hemp stalks is disclosed. The method and system use an entirety of the whole hemp stalks in producing the particulate hemp such that the particulate hemp comprises both bast fiber and shire of the original whole hemp stalks. Additionally, hemp crumbs or crumbles may be processed from whole hemp stalks, or from particulate hemp which is larger than the hemp crumbs such as hemp pellets. The hemp crumbs may be formed by crushing the hemp pellets.
METHOD FOR REMOVING CONTAMINANTS FROM CANNABINOID DISTILLATES
A method for removing contaminants such as pesticides and fungicides from cannabinoid extracts. Cannabinoid extracts containing contaminants may be dissolved in a water and ethanol solution, and then cooled to allow water-soluble contaminants to settle out of the mixture. The water and ethanol may then be removed via evaporation or distillation, leaving purified cannabinoids without contaminants. Contaminant removal may be incorporated into a method for producing a blended extract of cannabinoids and terpenes, which extracts terpenes using supercritical CO2, and extracts a cannabinoid concentrate from the residual material using a cold ethanol flush followed by distillation and then by contaminant removal; the CO2-extracted terpenes are then added back to the purified cannabinoid concentrate in a final blending step. Blending terpenes at the end of extraction may enhance the flavor and effectiveness of the purified cannabinoid concentrate.
ORGANIC MATERIAL PROCESSING SYSTEM
An extraction system comprises an extraction chamber having an end cap at an one end accepting organic matter and gas or liquid solvent. A collection vessel is attached below the extraction chamber, a viewing vessel is sealed at an acute angle to a sidewall of the collection vessel enabling visual inspection at the collection plate. A gas tank is connected to the extraction chamber introducing solvent and a frame supports chamber by axles fixedly mounted on opposite sides of the extraction chamber, said axles supported by the frame structure enabling free rotation of the chamber about the axles. After gas is introduced to the organic matter, the extraction chamber is rotated vigorously about the axis, the one end is then connected to the open upper end of the collection vessel, and a lipid yield is collected at the collection plate.
METHODS OF PREPARATION OF ZINGERONE, COMPOSITIONS COMPRISING ZINGERONE, AND USES THEREFOR
Disclosed are methods for preparing zingerone from ginger using alkaline solutions, as well as compositions obtained using these methods, and methods for using these compositions. Specifically disclosed are pharmaceutical compositions, and treatment methods employing zingerone in combination with other therapeutics such as gentamicin, vancomycin, and cefotaxime.