The invention relates to the use of a powder in a powder jet device for cleaning tooth surfaces by powder spraying, wherein the powder comprises cyclodextrin. The invention also relates to a process for cleaning tooth surfaces with a powder jet device, wherein the powder comprises cyclodextrin and the invention relates to a powder or powder mixture for use in a powder jet device, wherein the powder or powder mixture comprises cyclodextrin.

Provided is a method capable of manufacturing 1,3-butylene glycol having a high potassium permanganate test value. A method for manufacturing 1,3-butylene glycol, which is a method for obtaining purified 1,3-butylene glycol from a crude reaction liquid containing 1,3-butylene glycol, the method including: a dehydration step of removing water by distillation; a high boiling substance removal step of removing a high boiling point component by distillation; and a product distillation step of obtaining purified 1,3-butylene glycol, wherein in the product distillation step, a product column is used in which a liquid feed having a 1,3-butylene glycol concentration of 97% or higher, an acetaldehyde content of 500 ppm or lower, and a crotonaldehyde content of 200 ppm or lower is distilled under a condition of a reflux ratio of higher than 0.1, and a liquid concentrated with acetaldehyde and crotonaldehyde is distilled off from above a feed plate, and 1,3-butylene glycol is extracted from below the feed plate.

A high-purity 1,3-butylene glycol product is provided, which is colorless and odorless (or almost colorless and odorless), unlikely to cause coloration and odor over time, and, besides, unlikely to cause an acid concentration increase over time also in a state containing water. A 1,3-butylene glycol product in which at least one of a content of methyl vinyl ketone, a content of acetone, a content of butylaldehyde, a content of acetaldol, a content of a compound represented by Formula (1) below, a content of a compound represented by Formula (2) below, a content of a compound represented by Formula (3) below, and a total content of a compound represented by Formula (4) below and a compound represented by Formula (5) below, is less than 8 ppm.

Provided is a method capable of manufacturing high-purity 1,3-butylene glycol having a high potassium permanganate test value, a very low content of low boiling point components, and a high initial boiling point with a high recovery rate.

The method for manufacturing 1,3-butylene is a method for obtaining purified 1,3-butylene glycol from a crude reaction liquid containing 1,3-butylene glycol. In a dehydration column used in a dehydration step, a liquid feed containing 1,3 butylene glycol and water with an acetaldehyde content of 1000 ppm or lower and a crotonaldehyde content of 400 ppm or lower is distilled under a condition of a reflux ratio of higher than 0.3, and a liquid concentrated with a low boiling point component containing water is distilled off from above a feed tray. In a product column used in a product distillation step, a liquid feed containing 1,3-butylene glycol with an acetaldehyde content of 500 ppm or lower and a crotonaldehyde content of 200 ppm or lower is distilled under a condition of a reflux ratio of higher than 0.1.

The present invention provides topical compositions comprising a combination ascorbic acid, epigallocatechin gallate, water and 1,3-propanediol.

A method for preparing stable liquid emulsion forms of plant extract is provided. A plant extract having a bitter flavor is mixed with diluent oil as an oil mixture and heat is applied to the oil mixture. An emulsifying agent is dispersed in water as an emulsifying solution. The oil mixture is mixed with the emulsifying solution. The mixed oil mixture and emulsifying solution is homogenized as a liquid form of the plant extract. Gluconic acid is added to the liquid form of the plant extract. The bitter flavor of the plant extract is disguised by adding a bitter blocker to the liquid form of the plant extract.

Provided is a method capable of yielding high-purity 1,3-butylene glycol having a very low content of a high boiling point component and a low dry point, with a high recovery ratio. A method for producing 1,3-butylene glycol to yield purified 1,3-butylene glycol from a reaction crude liquid containing 1,3-butylene glycol, in which, in a high boiling point component removal column for use in the removing a high boiling point component, a charged liquid containing 1,3 -butylene glycol is distilled under conditions that (i) a reflux ratio is greater than 0.02 in a case where a concentration of 1,3-butylene glycol in the charged liquid is 95% or less, or a reflux ratio is greater than 0.01 in a case where the concentration of 1,3-butylene glycol in the charged liquid is greater than 95%, and (ii) a bottom ratio of less than 30 wt. %, high-purity 1,3-butylene glycol is distilled off from above a charging plate, and a liquid in which a high boiling point component is concentrated is extracted from below the charging plate.

The present invention relates to a method for separating and purifying melittin (Mn), apamin (Ap), mast cell degranulation (MCD) peptide and other components present in bee venom (BV). The method allows the beneficial components of the venom to be retained in the purified BV substance and allergens to be eliminated, using ultrafiltration and silica gel chromatography. The combination of the two techniques eliminates allergenic and harmful components, such as the enzymes phospholipase A2 (PLA2) and hyaluronidase (HYA), and a purified substance (referred to as “PDA”) is obtained from the venom. The invention also relates to an anti-ageing cosmetic product comprising the purified substance, wherein the cosmetic product is selected from a cosmetic serum.

Methods for producing a composition containing a hardly water-soluble aromatic compound are described which involve Step (1), including Step (1-1) for preparing a material comprising: (A) a hardly water-soluble aromatic compound, (B) a polyol, and (C) an aqueous medium, where a content of the (A) hardly water-soluble aromatic compound in the material for heating is below a saturation solubility of the (A) hardly water-soluble aromatic compound in a solvent having the same composition at 25° C. The obtained solution is then heated in Step (1-2) at normal pressure at a temperature of less than 100° C., to obtain a hardly water-soluble aromatic compound solution 1. Step (2) includes adding water to the hardly water-soluble aromatic compound solution 1 such that the resulting hardly water-soluble aromatic compound solution 2 has a concentration of the (A) hardly water-soluble aromatic compound above a saturation solubility at 25° C.

A Pickering formulation for use as a pharmaceutical or cosmetic composition for regenerating skin cells, allowing reducing skin stretch marks on a human skin, or healing skin cells after a burn, such as a sunburn. The Pickering formulation comprises an emulsion of oil and water phases stabilized with an organic-modified natural physosillicate, such as hectorite, montmori-Uonite, or bentonite. The pharmaceutical or cosmetic composition can be free of primary emulsifier or primary surfactant reducing as such the toxicity of the composition for the skin. As such, the pharmaceutical or cosmetic composition may consist essentially of the Pickering formulation. Indeed, it is demonstrated that the Pickering formulation can act itself as an active ingredient of the pharmaceutical or cosmetic composition leading to significant skin cell regeneration. The invention is particularly useful for reduction of stretchmarks. The Pickering formulation also boosts the sun protection factor, or SFP, of sunscreen compositions.