The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREBS, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.

The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREBS, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.

Odor control articles (10) including hydrophobic polymers of intrinsic porosity (HPIM) and their use in personal care products and hygienic products is disclosed. The odor control article (10) includes a HPIM and a colorant. The odor control article (10) may be applied to a substrate (11), and more specifically to a liquid absorbent member (30), to form an odor-absorbing member (20). The substrate (11) may absorb liquid. The odor-absorbing member (20) may be placed in such products as diapers (200), incontinence pads (60) and refrigerator pads. A method of making an odor control suspension with HPIMs including the use of surfactants is also disclosed. The odor control suspension may also be applied to a substrate (11).

Medical dressings and methods of using same. The medical dressing can include a fluid management article. The fluid management article can include a fibrous substrate and porous polymeric particles. At least 50% of the porous polymeric particles are bound to the fibrous substrate. Methods of using the medical dressings can include applying the medical dressing to the target site, such that the fluid management article is in fluid communication with the target site.

Medical dressings and methods of using same. The medical dressing can include a fluid management article. The fluid management article can include a fibrous substrate and porous polymeric particles. At least 50% of the porous polymeric particles are bound to the fibrous substrate. Methods of using the medical dressings can include applying the medical dressing to the target site, such that the fluid management article is in fluid communication with the target site.

Medical dressings having flexible and conformable borders when attached to skin and devices such as, e.g., catheters, etc. to facilitate strong adhesive securement of the medical dressings to skin over extended periods of time. The medical dressings include a relatively low modulus backing layer paired with a relatively high modulus support material the backing layer, and a tubing slot configured to, e.g., stabilize a catheter other tubing on the skin of a patient. The backing layer may extend outwardly from the support material over a substantial majority of the perimeter of the medical dressing to form a border of adhesive material with elasticity to resist lifting from a patients skin.

The inventive subject matter provides compositions and methods for transiently or permanently treating or managing an injury. Contemplated compositions are polymerizable in situ over short time periods, even in the presence of blood, without undue exothermic heat. Contemplated compositions may further comprise an anesthetic, an antiseptic, an adhesion promoter, and/or a vasoconstrictor.

The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyimide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.

The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyimide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.

Provided is an individually-wrapped sanitary napkin N, in which a sanitary napkin 1 is folded lengthwise with a wrapping sheet 10 and wrapped individually, the sanitary napkin 1 including an inner surface sheet 3 that constitutes a skin-contacting surface layer and a pair of wing-like flaps W that have wing adhesive layers 9 for fixing the wing-like flaps W to the underwear. The wing-like flaps W are both folded to the skin-contacting surface side, and the wing adhesive layers 9, provided in the folded portions of the wing-like flaps W, are collectively covered by a wing separating sheet 12, and a functional chemical 20 having a specific function is contained in the inner surface sheet 3 in the area where the wing separating sheet 12 is layered.