The invention relates to a composite material comprising polyaryletherketone, reinforcement fibre, and contrast agent. The reinforcement fibre is present in an amount of 52 to 58 volume % based on the total volume of the composite material.

The present disclosure relates to a composite material, in particular a composite material of metals, a process for producing a composite material, and a medical device, in particular an implant, based on the composite material. The composite material comprises at least 5 vol-% of Fe and at least 1 vol-% of Mg or Zn, wherein the composite material comprises a Mg or Zn phase and an Fe phase, wherein the average size of the Mg or Zn phase in at least one dimension is less than 20 μm, in particular less than 10 μm. The medical device, in particular an implant, may be suitable for fixing of bone fractures (as well as fractions of a tendon or a ligament, etc.) and/or corrections and may be capable of exhibiting a targeted failure representing a complete paradigm shift in the treatment of bone fractures and the like.

A mesh-based composition comprising a cross-linkable protein or polypeptide and one or more cross-linking materials according to at least some embodiments. The mesh-based composition may comprise a self-adhering surgical mesh which requires no additional fixation while at the same time minimizes adhesions. The mesh may be in the form of a composite mesh featuring a foamed composition of the cross-linkable protein and a non-toxic material that induces cross-linking of the cross-linkable protein. The composite mesh may be in a sheet-like form.

The invention relates to a biodegradable membrane on the basis of an organic-inorganic hybrid polymer, and to a process for producing same.

The invention relates to a biodegradable membrane on the basis of an organic-inorganic hybrid polymer, and to a process for producing same.

The present disclosure relates to the development of hydrogels with extreme stiffness and high-strength. In particular, an hydrogel comprising poly(2-hydroxyethyl methacrylate) and graphene material with a specific oxidation degree. The hydrogels of the present disclosure may be used in medicine, veterinary or cosmetic, namely as scaffold, cartilage, intervertebral disc and blood contact device such as: catheters, vascular grafts, heart valves, stents, artificial kidneys, artificial lungs, ventricular assist devices or drug delivery system. Uses in other areas can be envisaged, like in soft robotics, packaging, sealing and sensors.

The present disclosure provides an ophthalmic article. The ophthalmic article may comprise a biocompatible matrix comprising a copolymer derived from a caprolactone monomer and at least one other monomer. The ophthalmic article may also comprise an active agent or a diagnostic agent. The ophthalmic article may be configured to associate to a haptic of an intraocular lens (IOL).

A surgical clamping device is disclosed, having a first clamp jaw and a second clamp jaw, each having one or more channels configured for receiving suture for reliably securing the clamp jaws to maintain a clamping pressure during a surgical procedure, as well as to reliably and releasably secure the clamp jaws onto the introducer shaft of the clamping device. Also described are clamp jaws having one or more actuator interfaces and alignment guides configured for reversible and slidable engagement with an actuator at the end of an articulating introducer shaft. Also described are various features of clamp jaws for use with a surgical clamping device. Also disclosed is a surgical clamping device having detachable, pivotable first and second clamp jaws releasably held on pivotable fingers at a proximal end of an articulating introducer shaft. Related methods of surgical clamping procedures are also disclosed.

Systems and methods for imaging an object that are capable of capturing an image or images of the object using an imaging modality, automatically detecting and analyzing the image or images by way of converting the image or images to at least one binary image, and analyzing the at least one binary image to extract and/or segment regions-of-interest (ROIs) from the at least one binary image. The object can be or include an implantation, occlusion, medical device, body lumen, tissue, organ, duct, and/or vessel. The imaging modality can be or include X-ray, CT, MRI, PET, and/or ultrasound, or any combination thereof. Also included are compositions of soft, implantable materials with one or more carbon-based material, nanomaterial, and/or allotrope present in an amount sufficient as an ultrasound contrast agent effective for days, months, or years and which compositions are useful in the automated imaging methods of the invention.

A biomedical device includes a zinc-based material including a matrix including zinc, and nanostructures dispersed in the matrix. Embodiments of this disclosure are directed to zinc (Zn)-based materials including dispersed nanostructures for biomedical applications and devices, such as bioresorbable vascular stents, bioresorbable ureteral stents, endoluminal springs for distraction enterogenesis, biodegradable bone implants with tunable modulus, guided bone generation membranes, bioresorbable dental membranes, and other biomedical implants, as well as other functional applications, such as biodegradable electronics and sensors.