A composite lumen includes a braided structure infused with an impermeable elastic sealer. The braided structure has an inner diameter of 3 mm or less and a braid angle greater than 100°. The braided structure also has a wall thickness to inner diameter ratio greater than 0.02, picks per inch from between about 25 and about 135, and a number of ends between about 12 and about 48, with a braid pattern that is selected from 1×1, 2×2, or 2×1 and with an effective yarn denier (yarn denier×ply number) greater than 45.

A composite lumen includes a braided structure infused with an impermeable elastic sealer. The braided structure has an inner diameter of 3 mm or less and a braid angle greater than 100°. The braided structure also has a wall thickness to inner diameter ratio greater than 0.02, picks per inch from between about 25 and about 135, and a number of ends between about 12 and about 48, with a braid pattern that is selected from 1×1, 2×2, or 2×1 and with an effective yarn denier (yarn denier×ply number) greater than 45.

The present invention provides a surgical drape such that even when it is incised or punctured with a surgical tool in a state where it is pasted to an uneven surface having a low smoothness or to a part having a high curvature, such as a hand, a leg, or the head, a part subjected to incision or the like and its surroundings are unlikely to peel off, the surgical drape having excellent handling properties and safety. The surgical drape is a surgical drape 10 provided with a tacky layer 5 to be incised or punctured with a surgical tool, the tacky layer 5 having a tacky surface 2 to be brought into contact with a region including a surgery site of a living body. The surgical drape 10 has a Young's modulus of 10.0 MPa or less and may further be provided with a film-like base material 15 disposed by lamination on a surface on an opposite side of the tacky surface 2 of the tacky layer 5.

The present invention provides a surgical drape such that even when it is incised or punctured with a surgical tool in a state where it is pasted to an uneven surface having a low smoothness or to a part having a high curvature, such as a hand, a leg, or the head, a part subjected to incision or the like and its surroundings are unlikely to peel off, the surgical drape having excellent handling properties and safety. The surgical drape is a surgical drape 10 provided with a tacky layer 5 to be incised or punctured with a surgical tool, the tacky layer 5 having a tacky surface 2 to be brought into contact with a region including a surgery site of a living body. The surgical drape 10 has a Young's modulus of 10.0 MPa or less and may further be provided with a film-like base material 15 disposed by lamination on a surface on an opposite side of the tacky surface 2 of the tacky layer 5.

In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.

Methods for improving the antibacterial and/or bone-forming characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant may comprise a composite of a silicon nitride ceramic powder dispersed within a poly-ether-ether-ketone (PEEK) or a poly-ether-ketone-ketone (PEKK) substrate material. In some implementations, the biomedical implant may be 3D printed.

Methods for improving the antibacterial and/or bone-forming characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant may comprise a composite of a silicon nitride ceramic powder dispersed within a poly-ether-ether-ketone (PEEK) or a poly-ether-ketone-ketone (PEKK) substrate material. In some implementations, the biomedical implant may be 3D printed.

A magnesium-based bulk metallic glass composite includes a magnesium-based bulk metallic glass composite comprising a magnesium-based material and a TiZr alloy.

The present disclosure is directed toward composite materials comprising high aspect ratio habits of drug crystals which can be partially or fully extending into a substrate, and additionally, can be projecting from a substrate at an angle of about 20° to about 90°. The present disclosure is directed toward medical devices, such as medical balloons, comprising said composite and methods of using and making the same. The described composite can be used for the local treatment of vascular disease. The present disclosure is also directed toward paclitaxel crystals with a hollow acicular habit.

The present invention relates to a method of preparing reduced graphene oxide, incorporation of the reduced graphene oxide into polyisoprene latex to provide a polyisoprene latex graphene composite and elastomeric articles prepared using the polyisoprene latex-graphene composite. In particular, the reduction of graphene oxide is accomplished without the use of strong reducing agents and organic solvents and incorporation of the reduced graphene oxide into polyisoprene latex is accomplished using room temperature latex mixing method or hot maturation. The resultant composite exhibits good colloid stability, and polyisoprene latex films produced the composite exhibit good mechanical properties with improved ageing resistance.