A series of novel molecular conjugates is disclosed herein, consisting of a photosensitizer moiety chemically bonded to at least one diazirine moiety. Such conjugates react in air and/or water with non-coherent visible light to form singlet oxygen, an energetic species known to be highly toxic to abroad range of pathogens, including bacteria, fungi, microbial biofilms and viruses. Such non-specific cellular damage limits the pathogen's ability to evolve into a resistant form. The diazirine moiety of the conjugate enables the reagent to be adhesively bonded to a plethora of substrates, such as, for example, polymers, non-woven fabrics, surgical masks and gloves, hospital gowns, hospital surfaces (such as counters, mattresses, curtains) medical implants, bandages, wound dressings, or air-filters. The resulting treated substrates act as an effective pathogen-killing barrier, providing protection against the spread of such pathogens to non-infected persons.

A system and method for cleaning, rinsing, and sanitizing a container is disclosed. The system has a sanitizing agent chamber for storing a sanitizing agent, the one or more solution chambers in fluid communication with the container, a pump in fluid commination with the sanitizing agent, wherein the pump is in communication with a gas, and at least one spray nozzle fluidly connected to the at least one solution chamber via a conduit positioned within the container, wherein the spray nozzle comprises a housing inside which the sanitizing agent is mixed at pressure with the gas to disperse the sanitizing agent and gas mixture into the container for sanitizing the container.

An improved technology for inactivation of viruses, for example the SARS-CoV-2 virus that is causing the Covid-19 pandemic, is described. The technology can include a device that includes a substrate coated in a polymer that is infused with a pathogen inactivating material. In various embodiments, at a given time, a portion of the pathogen inactivating material is exposed to the environment, and the device is configured to periodically or intermittently expose additional pathogen inactivating material to the environment. For example, the polymer can be ablative or sacrificial.

An improved technology for inactivation of viruses, for example the SARS-CoV-2 virus that is causing the Covid-19 pandemic, is described. The technology can include a device that includes a substrate coated in a polymer that is infused with a pathogen inactivating material. In various embodiments, at a given time, a portion of the pathogen inactivating material is exposed to the environment, and the device is configured to periodically or intermittently expose additional pathogen inactivating material to the environment. For example, the polymer can be ablative or sacrificial.

A method of manufacturing a component for an aircraft interior having antimicrobial properties is disclosed. In various embodiments, the method includes applying a reactive quaternary ammonium ion-based compound (“reactive quat”) to an exposed surface of the component.

This patent is for a kill and protect surface disinfectant and a hand sanitizer for combatting contact infection spread. The kill and protect surface disinfectant composition is comprised of between about 0.20% (w/w) to about 1.00% (w/w) benzalkonium chloride; between about 0.25% (w/w) to about 3.00% (w/w) hydrogen peroxide; between about 0.25% (w/w) to about 0.75% (w/w) 3-(tri-methoxysilyl)propyldimethyl octadecyl ammonium chloride and between about 95.25% (w/w) to about 99.30% deionized water. The hand sanitizer is comprised of between about 0.05% (w/w) to about 0.20% (w/w) benzalkonium chloride; between about 0.20% (w/w) to about 0.50% (w/w) 3-(tri-methoxysilyl)propyldimethyl octadecyl ammonium chloride; between about 0.25% (w/w) to about 0.75% (w/w) phenoxyethanol and between about 98.55% (w/w) to about 99.5% (w/w) deionized water. The two work together to safeguard a community from contact infection spread.

Provided are methods of reducing and killing bacteria and fungi, and photodynamic treatment methods and sterilization methods using the methods of reducing and killing bacteria and fungi. The method of reducing and killing bacteria and fungi includes bringing a composition including a Ligularia fischeri extract or a fraction thereof as an active ingredient into contact with cells or tissues of a subject and irradiating cells or tissues of a subject in contact with the composition with an absorbable wavelength of excitation light.

A disinfectant and sanitizer canister system is disclosed. The system may include a pre-pressurized canister being pre-filled with one or more liquid cleaners and one or more propellants. The system may further include a valve sub-system including a dispensing valve and a valve control mechanism. The control mechanism may be configured to regulate the pressure of the pre-pressurized canister to cause the pre-pressurized canister to release the one or more liquid cleaners. The system may further include a dispensing sub-system configured to fluidically couple the pre-pressurized canister to the valve sub-system. The dispensing sub-system may include a dispensing member configured to dispense the one or more liquid cleaners contained within the pressurized canister. The system may further include a metering device, the metering device configured to provide a predetermined amount of pressure to dispense a predetermined metered dose of the one or more liquid cleaners.

Disclosed herein are articles (e.g., wearable articles, such as gloves and masks) comprising an antimicrobial material, and methods of manufacture thereof. In various embodiments, the antimicrobial material comprises dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium, or a salt thereof. In some embodiments, the antimicrobial article (e.g., a wearable article, such as a glove or mask) may have antiviral properties against coronavirus, such as SARS-CoV-2.

An improved technology for inactivation of viruses, for example the SARS-CoV-2 virus that is causing the Covid-19 pandemic, is described. The technology can include a device that includes a substrate coated in a polymer that is infused with a pathogen inactivating material. In various embodiments, at a given time, a portion of the pathogen inactivating material is exposed to the environment, and the device is configured to periodically or intermittently expose additional pathogen inactivating material to the environment. For example, the polymer can be ablative or sacrificial.