A composition for coating a medical device and a coated medical device are provided. The composition includes a polymeric matrix having non-toxic quantum dots or a fluorophore or both. The polymeric matrix contains the quantum dots or fluorophore and binds as a coating to the medical device. Coated medical devices can be readily identified within or outside of a body and in open or laparoscopically surgeries, greatly reducing or eliminating the risk of a retained foreign object.

Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.

A balloon catheter is disclosed having a balloon at a distal portion of a catheter shaft and on a surface of the balloon are elongate bodies which are crystals of a water-insoluble drug having independent long axes. The balloon in a deflated state has a plurality of wing portions in a circumferential direction of the balloon, and a circumferential surface portion along a circumferential direction of the catheter shaft, the plurality of wing portions being folded along the circumferential direction of the balloon. A surface of the circumferential surface portion which faces the plurality of wing portions that are folded has a region in which tip portions are not in contact with the surface of the balloon or with other elongate bodies, and a surface which faces the plurality of wing portions that are folded which faces an outer circumferential side has a region in which the tip portions are in contact with the surface of the balloon or with the other elongate bodies.

The dental coating composition of the present invention is suitable to coat dental prosthetics. The composition is a mixture of a (meth)acrylate dimer, a (meth)acrylate crosslinker, a photoinitiator, and a silicone surfactant, and optionally, a (meth)acrylate monomer with a heteroalkyl group, a colorant, special effects pigment, particles, and other additives. Incorporating particles in the dental coating formulation provides a “character” to the surface of the dental prosthetic, increasing the esthetic appeal of the prosthetic. The dental coating thus may make the parts of the dental prosthetic appear to approximate gingivae, or gum. The dental coating composition may be applied to a surface of an unfinished dental prosthesis prior to curing, to a partially cured prosthesis, or fully cured prosthesis.

A bioactive filamentary structure includes a sheath coated with a mixture of synthetic bone graft particles and a polymer solution forming a scaffold structure. In forming such a structure, synthetic bone graft particles and a polymer solution are applied around a filamentary structure. A polymer is precipitated from the polymer solution such that the synthetic bone graft particles and the polymer coat the filamentary structure and the polymer is adhered to the synthetic bone graft particles to retain the graft particles.

Antimicrobial formulations and coatings for medical devices and processes therefor are disclosed. The formulations include at least one water permeable polymer with at least one antimicrobial agent in a liquid medium and are prepared by wet milling the components and can form antimicrobial coatings having uniformly dispersed particles having an average size of no greater than 50 microns.

A medical device, such as a catheter, is disclosed, comprising a substrate and having on its surface, on at least a part thereof, a hydrophilic surface layer providing low-friction surface character of the medical device when wetted by a wetting fluid. At least one base layer of the substrate, including the hydrophilic surface layer, is made of a polymer blend comprising at least one base polymer and at least one hydrophilic polymer, and wherein the concentration of the at least one hydrophilic polymer is higher in the hydrophilic surface layer than in the rest of the base layer. A method for producing such a medical device is also disclosed.

An implant for eye disease for controlling intraocular pressure, the implant including a coating layer formed on the outside of an implant substrate. Specifically, the present invention relates to an implant that may suppress a foreign body reaction from occurring around the implant, because the implant includes a coating layer, which is formed on the outside of an implant substrate and is a cured product of a polymer of a composition containing an acrylate-based monomer and a (meth)acryloyloxyethyl phosphorylcholine monomer.

A health care and/or entertainment device protective film may be configured to contact human skin, e.g., to limit the transmission of infection by bacteria, fungi, protozoa, prions, and/or viruses. The film may be formed as a nanocomposite film including at least 75 wt. %, relative to total organic matrix weight, of polyethylene, silver particles, and TiO.sub.2 particles, wherein the silver particles and TiO.sub.2 particles are distributed within and/or on an outer surface of the polyethylene, wherein the silver particles have a size of 1 to 1,000 nm, and wherein the TiO.sub.2 particles have a size of 1 to 50 nm. Such films may be applied to health care and/or entertainment devices, including virtual reality googles.

The invention relates to balloon coatings and their use in delivering drugs via a drug-eluting balloon. The delivery can be, e.g., to a vessel wall.