A method for promoting growth of bone, periodontium, ligament, or cartilage in a mammal by applying to the bone, periodontium, ligament, or cartilage a composition comprising platelet-derived growth factor at a concentration in the range of about 0.1 mg/mL to about 1.0 mg/mL in a pharmaceutically acceptable liquid carrier and a pharmaceutically-acceptable solid carrier.

Disclosed are implants, devices and related manufacturing methods for implants comprising material mixtures including silicon nitride and/or other material additives in some of all of the implant body, including portions, layers and/or surface coatings thereof, for use as orthopedic implants such as joint and/or bone replacement implants used in in spinal surgeries, dental surgeries and/or other orthopedic procedures.

The invention relates to a method for manufacturing a calcified tissue substitute, the method comprising: reacting ground nacre, monocalcium phosphate, and water to produce brushite; grinding the brushite; reacting ground nacre with the ground brushite in disodium hydrogenphosphate solution. The invention also relates to a calcified tissue substitute manufactured by the method, use of the calcified tissue substitute for repairing a calcified tissue, and a delivery device for delivering the calcified tissue.

Described are ready-to-use injectable compositions comprising polymeric microspheres or microparticles of non-animal origin, a hydrogel comprising water and a cellulose-derivative gelling agent, and polysorbate 80. Further described are methods of using the ready-to-use injectable compositions for reparative or plastic surgery, esthetic dermatology, facial contouring, body contouring, and gingival augmentation.

Various embodiment related to methods for coating a metal substrate with a silicon nitride ceramic coating are disclosed herein. The metal substrate may be a biomedical implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

The invention relates to a method of producing an implantable collagen-containing medical device comprising the step of coating said collagen-containing medical device with metal microparticles and/or metal nanoparticles, wherein said step of coating said collagen-containing medical device is by sonication such that the collagen-containing medical device has anti-bacterial and anti-inflammatory properties on implantation compared to the medical device not coated with metal microparticles and/or metal nanoparticles.

The invention relates to the application of a composition containing recombinant amelogenin and propylene glycol alginate (“PGA”) on to cut dentin tubules followed by installation of a definitive restorative in a single visit.

The present invention provides a material composition and a process of producing translucent ZrO.sub.2—SiO.sub.2 nanocrystalline glass ceramic (NCGC) with ultra-high flexural strength. The method comprises the following step: (1) prepare homogenous ZrO2-SiO2 nano-sized powder with high purity via a sol-gel method; (2) pressure assisted sintering of ZrO2-SiO2 nano-sized sol-gel powder to obtain translucent ZrO2-SiO2 NCGC. The invention also includes materials manufactured using the method.

The present disclosure provides a dental implant packaging container including: a see-through body unit in which upper and lower sides are open to form an accommodation space so that a dental implant fixture is accommodated therein and which is made of a material through which UV light for surface modification passes; a first cap unit which includes a hollow first cap body configured to cover an upper end portion of the accommodation space, a first fixing part protruding from a lower portion of the first cap body and having a coupling surface formed on an outer side portion, and a protruding part provided to protrude from the first fixing; a hollow holder unit which has an outer circumferential portion coupled to an inner circumference of the see-through body unit and an inner circumferential portion coupled to the coupling surface to mediate the connection between the see-through body unit and the first cap unit; and a second cap unit which includes a second fixing part fitted and coupled to a lower end portion of the see-through body unit and a base part provided on an inner side end of the second fixing part so that a lower end portion of the fixture is seated thereon.

The present invention relates to an abutment of a dental implant system for connecting a dental implant and a suprastructure, said abutment comprising an abutment basic body extending from an apical end to a coronal end arranged opposite to the apical end. The abutment basic body comprises a dental implant connecting portion facing the apical end and adapted to fit with a corresponding abutment connecting portion of the dental implant and/or an intermediate part to be directly or indirectly connected with the dental implant. It further comprises a support portion facing the coronal end and designed such to allow the suprastructure to be mounted directly or indirectly. According to the invention, the abutment further comprises nanostructures formed on at least a portion of the outer surface of the abutment basic body, said nanostructures extending in at least two dimensions to 200 nm at most.