A needleless injector pressurizes a substance to be injected having an ejection pressure defined as a pressure of the substance to be injected ejected through an ejection port. The ejection pressure is raised to a first peak pressure after pressurizing is started, is lowered to a pressure lower than the first peak pressure afterward, and then is raised to a second peak pressure again. An on-completion reached depth that is an on-completion reached depth of the substance when the pressurizing portion completes pressurizing is adjustable, the on-completion reached depth being increased along with increase of the first peak pressure and being increased along with reduction of a length between peaks from a first timing at which the ejection pressure reaches the first peak pressure to a second timing at which the ejection pressure reaches the second peak pressure.

A needle syringe has a plunger and a needle for filling and dispensing liquid from the cavity. The cavity has finger clip with movable locking pins. The plunger has at least one set of grooves corresponding to a specific dosage for the needle syringe, the specific dosage of the groove being demarked by a marking ledge that indicates a change to a deeper depth section of the groove. The locking pins are configured to rest in the at least one set of grooves, such that when the plunger is removed, the locking pins pass within a first shallow section of the groove, pass over the ledge, and continue to pass in the deeper depth section of the groove. When the plunger is depressed in a first partial dispensing movement, the locking pins pass in the deeper depth section of the groove until the plunger depression is temporarily locked when the locking pins reach the ledge, where the dose remaining in the cavity is the specific dosage.

A needle syringe has a plunger and a needle for filling and dispensing liquid from the cavity. The cavity has finger clip with movable locking pins. The plunger has at least one set of grooves corresponding to a specific dosage for the needle syringe, the specific dosage of the groove being demarked by a marking ledge that indicates a change to a deeper depth section of the groove. The locking pins are configured to rest in the at least one set of grooves, such that when the plunger is removed, the locking pins pass within a first shallow section of the groove, pass over the ledge, and continue to pass in the deeper depth section of the groove. When the plunger is depressed in a first partial dispensing movement, the locking pins pass in the deeper depth section of the groove until the plunger depression is temporarily locked when the locking pins reach the ledge, where the dose remaining in the cavity is the specific dosage.

A device for inserting at least one hollow needle for the injection or withdrawal of a solution into/from a tissue, said device comprising a casing (1), a plunger (2) movably mounted inside the casing, and propulsion means (3 and 4) suitable for driving the plunger towards the distal end (1a) of the device by applying a force F1(t). The propulsion means and/or the plunger comprise retaining means (3a) for joining the propulsion means and the plunger while the latter is moving, said retaining means releasing the plunger from the propulsion means when a force F2(t) is exerted in the opposite direction to F1(t). Pressure means hold the needle in the tissue and allow a controlled withdrawal of the plunger at least while the solution is being injected.

A device for inserting at least one hollow needle for the injection or withdrawal of a solution into/from a tissue, said device comprising a casing (1), a plunger (2) movably mounted inside the casing, and propulsion means (3 and 4) suitable for driving the plunger towards the distal end (1a) of the device by applying a force F1(t). The propulsion means and/or the plunger comprise retaining means (3a) for joining the propulsion means and the plunger while the latter is moving, said retaining means releasing the plunger from the propulsion means when a force F2(t) is exerted in the opposite direction to F1(t). Pressure means hold the needle in the tissue and allow a controlled withdrawal of the plunger at least while the solution is being injected.

An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.

An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.

An injection capsule for medical use, having: a closed main body having an internal reservoir receiving a medical substance in liquid form to be administered to a target subject; and a needle, having one or more inlet bores located at its lateral skirt and configured to allow the inlet of the medical substance within its tubular body. The needle is activatable between a rest configuration, wherein it is housed within the reservoir and immersed in the medical substance, and an injection configuration, wherein it is pushed outside the closed main body to administer the medical substance by injection to the target subject.

An injection capsule for medical use, having: a closed main body having an internal reservoir receiving a medical substance in liquid form to be administered to a target subject; and a needle, having one or more inlet bores located at its lateral skirt and configured to allow the inlet of the medical substance within its tubular body. The needle is activatable between a rest configuration, wherein it is housed within the reservoir and immersed in the medical substance, and an injection configuration, wherein it is pushed outside the closed main body to administer the medical substance by injection to the target subject.

Drug delivery member insertion depth sensing assemblies, drug delivery devices, and methods for determining an insertion depth of a drug delivery member are disclosed. The sensing assemblies can include electrical sensing assemblies with direct or indirect measurement components or optical sensing assemblies with one or more light sources and one or more photodiodes. A controller of the sensing assemblies can receive data associated with the drug delivery member in an insertion position. The data can then be correlated to an insertion depth of the drug delivery member.