Systems and methods for mitigating the formation of heterotopic ossification lesions by delivering a neuromuscular inhibitor employ a delivery device to distribute injection of the neuromuscular inhibitor. A delivery device for delivering the neuromuscular inhibitor can include an injector body, a device body for spacing the injector body from a target delivery location, and a plurality of needles; or can include an injector guide having multiple guide holes and an injector needle for delivering the neuromuscular inhibitor via the guide holes.

Systems and methods for mitigating the formation of heterotopic ossification lesions by delivering a neuromuscular inhibitor employ a delivery device to distribute injection of the neuromuscular inhibitor. A delivery device for delivering the neuromuscular inhibitor can include an injector body, a device body for spacing the injector body from a target delivery location, and a plurality of needles; or can include an injector guide having multiple guide holes and an injector needle for delivering the neuromuscular inhibitor via the guide holes.

Disclosed are various embodiments of an auto-injector device that automatically and dynamically adjusts the depth that a needle will penetrate into a target area of the body. In one embodiment, the auto-injector device includes the needle being moveably disposed within a needle housing. The auto-injector device further includes a needle depth estimator having a needle depth limiter that extends into an inner portion of the needle housing and is designed to engage with a needle stop of the needle and restrict downward movement of the needle. The needle depth estimator can automatically adjust a position of the needle depth limiter within the needle housing according to movement of a compression mechanism surrounding a lower portion of the needle housing.

Disclosed are various embodiments of an auto-injector device that automatically and dynamically adjusts the depth that a needle will penetrate into a target area of the body. In one embodiment, the auto-injector device includes the needle being moveably disposed within a needle housing. The auto-injector device further includes a needle depth estimator having a needle depth limiter that extends into an inner portion of the needle housing and is designed to engage with a needle stop of the needle and restrict downward movement of the needle. The needle depth estimator can automatically adjust a position of the needle depth limiter within the needle housing according to movement of a compression mechanism surrounding a lower portion of the needle housing.

An infusion set, patch pump, or elements thereof, having an exemplary catheter (14) provided with one or more channels, grooves and coatings (24, 34, 44), configured and arranged to provide a degree of strength and flexibility. The catheter (14) can also have an exemplary flexible union with the hub (12) having at least one of a ball-and-socket joint (66, 68), a sliding plate (86), and a flexible bushing (106), and which is sealed to allow even further movement of the catheter (14) while preventing leakage of medication through the junction. In doing so, a number of benefits associated with the use of rigid materials in catheter construction can be provided while at the same time, benefits associated with the use of flexible materials in catheter construction and/or flexible engagement with the hub can also be provided.

An infusion set, patch pump, or elements thereof, having an exemplary catheter (14) provided with one or more channels, grooves and coatings (24, 34, 44), configured and arranged to provide a degree of strength and flexibility. The catheter (14) can also have an exemplary flexible union with the hub (12) having at least one of a ball-and-socket joint (66, 68), a sliding plate (86), and a flexible bushing (106), and which is sealed to allow even further movement of the catheter (14) while preventing leakage of medication through the junction. In doing so, a number of benefits associated with the use of rigid materials in catheter construction can be provided while at the same time, benefits associated with the use of flexible materials in catheter construction and/or flexible engagement with the hub can also be provided.

An infusion set adapted to be secured to a skin surface includes a fixed base member and a movable slide member. The fixed base member is connectable to the skin surface. The movable slide member has a needle or cannula connected thereto and is movable relative to the fixed base member. The movable slide member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. The movable slide member is locked to the fixed base member in the second position.

Needles are deployed in tissue under direct ultrasonic or other imaging. To aid in deploying the needle, a visual needle guide is projected on to the image prior to needle deployment. Once the needle guide is properly aligned, the needle can be deployed. After needle deployment, a safety boundary and treatment region are projected on to the screen. After confirming that the safety boundary and treatment regions are sufficient, the patient can be treated using the needle.

A system for providing a real-time indication of a location of the distal tip of a medical device in living tissue. The system may include an injection scanning printer that provides a visual indication of detected features to improve the injecting process. Safety needles configured to detect nerves, arteries, veins, or other physiological features upon needle placement but prior to injecting are also provided.

A system for providing a real-time indication of a location of the distal tip of a medical device in living tissue. The system may include an injection scanning printer that provides a visual indication of detected features to improve the injecting process. Safety needles configured to detect nerves, arteries, veins, or other physiological features upon needle placement but prior to injecting are also provided.