A sensor system capable of detecting tissue counter pressure from patients that utilize infusion pumps to administer their medication is provided. Embodiments include a retrofitted piece that is placed between the user's infusion set and pump, as well as a “smart” infusion set configured for measuring characteristics of a fluid traveling therethrough. Hardware is provided that couples with the sensor to store, analyze, and compare data to distinguish between normal and non-normal injection/infusion profiles. An alert system notifies the user of a malfunction within the pump, within the infusion set, or at the injection/infusion site.

An injection endpoint signalling assembly is provided that is adapted and configured for mounting on, and use with, a pre-filled syringe. The injection endpoint assembly is configured to prevent a signalling of an injection endpoint before the plunger of the pre-filled syringe has reached a limit of a permitted extent of a direction of injection travel. The assembly is further configured to enable the signalling of the injection end point when the plunger of the pre-filled syringe has reached the limit of the permitted extent of the direction of injection travel and is prevented from moving in a direction of travel different to the direction of injection travel.

Needle insertion mechanisms include a housing and a needle holder, the needle holder being linearly guided by the housing to be moved along the needle-axis. A slider linearly guided by the housing and transversally moveable with respect to the needle-axis from a first to a second slider position. The needle holder is operatively coupled to the slider when the slider is in the first position, thereby retaining the needle holder in a retracted position against the bias of a spring acting on the needle holder. In the second position the slider is decoupled from the needle holder and the holder is moved into an inserted position by the spring. A blocking member arranged between the slider and the housing blocking movement of the slider into the second position, is moved by an active drive thereby unblocking the movement of the slider and subsequently moving the slider to the second position.

Needle insertion mechanisms include a housing and a needle holder, the needle holder being linearly guided by the housing to be moved along the needle-axis. A slider linearly guided by the housing and transversally moveable with respect to the needle-axis from a first to a second slider position. The needle holder is operatively coupled to the slider when the slider is in the first position, thereby retaining the needle holder in a retracted position against the bias of a spring acting on the needle holder. In the second position the slider is decoupled from the needle holder and the holder is moved into an inserted position by the spring. A blocking member arranged between the slider and the housing blocking movement of the slider into the second position, is moved by an active drive thereby unblocking the movement of the slider and subsequently moving the slider to the second position.

A medicine administration system includes a medicine administration device, a medicine cartridge receivable with the medicine administration device, and a contrast background. The medicine cartridge is configured to retain medicine therein. The medicine administration device is configured to dispense at least some of the medicine through a dispensing end of the medicine cartridge. The contrast background is positioned relative to the medicine cartridge to permit visualization of the contrast background through the medicine within the medicine cartridge. The contrast background is configured to facilitate image processing of a captured image of the contrast background through the medicine within the medicine cartridge to determine a condition of the medicine within the medicine cartridge.

Systems and methods for delayed delivery of a drug are disclosed. A drug delivery system may include a delivery member for insertion into a patient and a reservoir configured to receive a volume of a drug. An energy source may be activatable by the patient to actuate the reservoir to deliver the drug to the patient as a single bolus. A lockout system may be configured to have a locked state, wherein the lockout system prevents movement of the delivery member and/or activation of the energy source, and an unlocked state, wherein the lockout system permits movement of the delivery member and/or activation of the energy source. The lockout system may be configured to automatically change from the locked state to the unlocked state after a preselected time period has elapsed. An output element may generate a detectable output after the preselected time period has elapsed for notifying the patient.

An injection device includes a cylinder having a cavity for receiving a liquid. A passage is connected to the cavity for inflow and/or outflow of the liquid. The passage can be connected to an injection component. A shut-off valve has a valve body and a flexible sealing ring with an opening. The valve body, proceeding from a release position in which the passage is freed, is at least partially movable through the opening of the sealing ring to a blocking position in which the valve body engages behind the opening so that movement of the valve body to the release position is blocked and the passage is sealed off against proximally directed flow. An adapter body is connected to the cylinder. The shut-off valve is arranged at a proximal end of the adapter body and at a distal end of the cylinder. The device can be used in a syringe.

Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.

A medical device includes a first housing portion (FHP) and a second housing portion (SHP) configured to be to be movable relative to each other from a first position to operatively engage at a second position to couple at least one of a drive device and a needle-inserting device supported by one of the FHP and the SHP to a reservoir supported by the other of the FHP and the SHP. Electronic circuitry configured to detect at least one of a first magnetic interaction between a magnet and at least one of a first magnetically attractive material and a first magnet-responsive device and a second magnetic interaction between the magnet and at least one of a second magnetically attractive material and a second magnet-responsive device, and to provide a signal or a change in state in response to detecting at least one of the interactions.

A needle and syringe system, wherein a needle head is attached to a syringe assembly. The syringe assembly includes a syringe barrel and a plunger rod with a plunger head. A needle base is affixed to the syringe barrel. A tubular cavity is formed in the needle base and a post extends through the tubular cavity. A needle extends through the post. A spacer is provided. The spacer is displaced into the tubular cavity within the needle base as the plunger head is advanced within the syringe barrel. A protective cover is disposed about the needle base. The spacer moves the protective cover between a first position and a second position as the spacer is displaced into the tubular cavity. As the protective cover moves between positions, the protective cover surrounds the needle and prevents the needle from causing any inadvertent needle stick injuries.