A portable device for treatment of migraine having a desktop unit defining an airpath through a desiccant, a heat sink, an air mover and an air outlet, and a tubeset including a tube having one end for connecting to the desktop air outlet and a second end connected to a handheld unit, the handheld unit including a water compartment, and a nebulizer/transducer for introducing water droplets into the air stream. A nasal pillow is provided at the end of the handheld unit for placing against a user's nose.

A mist inhaler device (200) for generating a mist comprising a therapeutic for inhalation by a user. The device comprises a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

A hookah device (202) which attaches to a hookah (246). The hookah device (202) comprises a plurality of ultrasonic mist generator devices (201) for generating a mist for inhalation by a user. The hookah device (202) comprises a driver device (202) which controls the mist generator devices (201) to maximize the efficiency of mist generation by the mist generator devices (201) and optimize mist output from the hookah device (202).

There is provided a nebulizer (2), comprising a first plate (20) configured to hold a transducer (14); a second plate (22) having an aperture therein, the first plate being positioned on a first side of the second plate such that the transducer is adjacent the aperture; and a third plate (24) configured to hold a mesh plate through which liquid can pass to form droplets, the third plate being positioned on a second side of the second plate opposite the first side such that the mesh plate (16) is adjacent the aperture, with the aperture, transducer and mesh plate forming a cavity for holding liquid to be nebulized. A method for manufacturing such a nebulizer is also provided.

A hand-held or wearable device for cooling tissue of an eye of a patient is disclosed. In one aspect, the device includes a reservoir having fluid therein and a support connected to the reservoir and configured to be positioned on a face of the patient. The device also includes a nozzle positioned proximate to the support and fluidically connected to the reservoir, the nozzle configured to pass the fluid from the reservoir onto a surface of the eye. The device further includes a cooling element configured to cool the fluid from the reservoir such that it exits the nozzle at a temperature of between −100° C. and 15° C. The device further includes an ultrasonic vibrator positioned near the nozzle and configured to generate mist from at least part of the fluid.

In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

A method for estimating an inhale dose when a drug is delivered to a person using an inhaler is disclosed. A predicted inhale dose (PID) of the drug is estimated based on at least one first-type parameter and at least one second-type parameter. The first-type parameter is related to a breath pattern of the person, and the second-type parameter is related to the inhaler.

An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

A prepuce extruding, cutting, hemostasis, and healing assembly using ultrasonic wave. Ultrasonic wave is applied in extruding, cutting, hemostasis, and healing of prepuce at a conjunction of internal and external tissues of a distal part of a human body. The assembly includes an ultrasonic generating device, a transmission device and a circumcision device. The ultrasonic generating device is used for generating ultrasonic waves, is connected to the transmission device and can send the ultrasonic waves to the transmission device. The transmission device is connected to the circumcision device and can send the ultrasonic waves to the circumcision device. The circumcision device is used for extruding and cutting a prepuce and/or performing hemostasis and/or healing of wounds. In this way, circumcision can be completed within just several seconds, and immediate healing can be achieved, preventing bleeding during and after a surgery.

A mount provides a structure that facilitates coupling of a nebuliser downstream of a humidifier chamber and upstream of a conduit that delivers conditioned breathing gases to a patient or user. The mount can couple together a chamber, a nebulizer and a conduit.