A fluid jet ejection device, a method of making a fluid jet ejection head for a fluid ejection device, and a method of improving the plume characteristics of fluid ejected from the fluid jet ejection head. The fluid jet ejection device includes a cartridge body; and a fluid jet ejection cartridge disposed in the cartridge body. The fluid jet ejection cartridge contains a fluid and an ejection head attached to the fluid jet ejection cartridge. The ejection head contains a plurality of fluid ejectors thereon and a nozzle plate having a plurality of fluid ejection nozzles therein associated with the plurality of fluid ejectors, wherein a first portion of the plurality of fluid ejection nozzles have a first axial flow path length and a second portion of the plurality of fluid ejection nozzles have a second axial flow path length greater than the first axial flow path length.

A method of administering C60 to a user includes combining C60 molecules with a limonene composition to form a C60 mixture, heating the C60 mixture to a predetermined temperature for a predetermined time period to dissolve the C60 molecules into the limonene composition to form a dissolved C60 mixture, and administering the dissolved C60 mixture to a nasal cavity of the user via nasal administration.

A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.

A mist inhaler device (200) for generating a mist including a therapeutic for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

A hookah device (202) which attaches to a hookah (246). The hookah device (202) comprises a plurality of ultrasonic mist generator devices (201) for generating a mist for inhalation by a user. The hookah device (202) comprises a driver device (202) which controls the mist generator devices (201) to maximize the efficiency of mist generation by the mist generator devices (201) and optimize mist output from the hookah device (202).

Methods for the treatment of pulmonary cancers (primary, secondary, metastatic, etc.) using an electronic breath actuated droplet delivery device to deliver a cancer therapeutic directly to the pulmonary system of a subject in need thereof is disclosed. An in-line droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The in-line droplet delivery device includes a housing, an ejector mechanism, and at least one differential pressure sensor. The in-line droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The in-line droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 μm, so as to target the pulmonary system of the user.

An inhaler configured and adapted for inhaling an inhalation medium, enriched with active ingredients and/or flavouring substances, includes a cartridge carrier, a storage tank which contains the inhalation medium, a mouthpiece which is associated with the cartridge carrier, and an actuating mechanism for releasing the inhalation medium out of the storage tank in the direction of the mouthpiece. The inhaler has at least one sensor associated with the mouthpiece. The sensor is configured and adapted to detect characteristics of lips of the person using the inhaler and to provide a data signal formed from the characteristics. The sensor is connected to an electronic control unit associated with the inhaler, to which the actuating mechanism is also connected, in such a manner that the inhalation medium is released on the basis of the data signal. A corresponding arrangement and a corresponding method are disclosed.

Methods and compositions for treating mTBI, PTSD or mTBI with PTSD with psychedelic agents and N-acetylcysteine are provided. Nasal mist transducers for administration of one or more pharmaceutically active ingredients such as these as fine mist particles at preselected dosages and times are also provided.

Introduced here is a self-contained face mask system with an automated liquid-droplet dispensing mechanism (ADM) for humidification. The enclosure of the self-contained mask system can be comprised of one or more layers of breathable fabric adapted to flexibly conform to the face of a user when worn to form a cavity that is adjacent the nostrils and mouth. The ADM of the face mask system can be comprised of a reservoir in which liquid is stored, a respiratory cycle detector, a timer and controller, and a droplet dispenser that controllably dispenses droplets of the liquid from the reservoir into the cavity for inhalation by the user. The ADM can be contained entirely within the face mask enclosure or supported on the surface of the face mask enclosure such that the self-contained mask system, when worn by a user, can be supported entirely by the head and neck of the user.

Systems and methods are provided for generating and applying biomimicry tear film layers to a cornea surface. An example method includes forming a multiple layered tear film that are optically transparent, ultra-thin, and smoothly conforming to cornea surface. The multiple layered tear film can include a biomimicry adhesive layer, a biomimicry aqueous layer, and a biomimicry lipid layer. An atomizer/nebulizer/micronizer can be used to generate and applying the biomimicry tear film layers.