This disclosure pertains to devices and methods for administering one or more active ingredients, e.g., cannabinoids, terpenes, etc. In particular, the devices and methods disclosed herein administer one or more cannabinoids in a mist for transmucosal and transdermal absorption. In one embodiment, the device contains compositions comprising purified active ingredients (e.g., cannabinoids, terpenes, etc.) and/or unique combinations thereof for delivery via a mist for transmucosal and transdermal adsorption. In one embodiment, the device contains two separate compositions in separate chambers, wherein each composition comprises one or more of the active ingredients. In one embodiment, a composition in one chamber comprises a purified cannabinoid and the composition in the other chamber comprises a purified terpene. In an embodiment, the device operates without heating the active ingredients.

The present invention is directed to a single-layer cartridge, and a process for producing a plastic single-layer container included in the cartridge. The single-layer cartridge comprises a plastic single-layer container, a seal and a nozzle-shaped cap or stopper, wherein the single-layer cartridge can be used to connected with a soft mist inhalation device or inhalation atomizer.

Cartridges are configurable between a closed state and an open state. The cartridges include a cartridge body and a reservoir disposed in the cartridge body. The cartridge body has an outer locking element, and the reservoir has a rotational locking element. In the closed state, the outer locking element engages the rotational locking element such that the reservoir cannot be rotated out of a first rotational position relative to the cartridge body in which a fluid outlet of the reservoir is not in fluid communication with a fluid outlet of the cartridge body. In the open state, the outer locking element of the cartridge body does not engage the rotational locking element of the reservoir, and the reservoir is in a second rotational position relative to the cartridge body such that the fluid outlet of the reservoir is in fluid communication with the fluid outlet of the cartridge body.

A nebulizer as well as a container with a fluid for such a nebulizer are proposed. The container comprises a control device which indicates initially an unused state of the container before first use. An indicator device stops via a locking device further use of the container in a locked state when a predetermined number of uses has been reached or exceeded. After replacement of the container, the nebulizer can be reset and used again.

Apparatus and methods for delivering humidified breathing gas to a patient are provided. The apparatus includes a humidification system configured to deliver humidified breathing gas to a patient. The humidification system includes a vapor transfer unit and a base unit. The vapor transfer unit includes a liquid passage, a breathing gas passage, and a vapor transfer device positioned to transfer vapor to the breathing gas passage from the liquid passage. The base unit includes a base unit that releasably engages the vapor transfer unit to enable reuse of the base unit and selective disposal of the vapor transfer unit. The liquid passage is not coupled to the base unit for liquid flow therebetween when the vapor transfer unit is received by the base unit.

The invention relates to a spray device having a spray nozzle unit and at least one further spray nozzle unit. Each spray nozzle unit has at least one spray nozzle body, wherein said at least one spray nozzle body comprises a chamber for receiving a pressurized fluid. Said chamber is bounded by a spray wall having at least one spray orifice that extends through said spray wall and opens to an external environment. Each of said at least one orifice in a spray wall has a substantially identical predetermined size lying in a predetermined range and releases a mono disperse spray jet of the pressurized fluid fed from the associated reservoir. Said range within said first spray nozzle unit differs from said range within said at least one further spray nozzle unit, particularly said ranges do not overlap.

A smart vaporizer that uses a vibrating mesh nebulizer with water based liquids that tracks the type of liquid, dosage inhaled, time, and user then transmits that information to smart devices such as smart phones and smart watches which then transmits back to the vaporizer additional data related to user weight, body fat, heart rate, blood pressure, temperature, movement, sleep, blood sugar, and medication usage to determine when metered amounts of said liquid may be inhaled by a user.

The invention features a pharmaceutical suspension containing drug particles, a drug delivery device anchored in the mouth for continuously administering the pharmaceutical suspension, and methods of their use.

A system for treating or providing prophylaxus against a pulmonary infection is disclosed comprising: a) a pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition, and b) an inhalation delivery device. A method for providing prophylaxis against a pulmonary infection in a patient and a method of reducing the loss of antiinfective encapsulated in a lipid-based composition upon nebulization comprising administering an aerosolized pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition is also disclosed.

Apparatus and methods for delivering humidified breathing gas to a patient are provided. The apparatus includes a humidification system configured to deliver humidified breathing gas to a patient. The humidification system includes a vapor transfer unit and a base unit. The vapor transfer unit includes a liquid passage, a breathing gas passage, and a vapor transfer device positioned to transfer vapor to the breathing gas passage from the liquid passage. The base unit includes a base unit that releasably engages the vapor transfer unit to enable reuse of the base unit and selective disposal of the vapor transfer unit. The liquid passage is not coupled to the base unit for liquid flow therebetween when the vapor transfer unit is received by the base unit.