The present disclosure includes dental appliances and methods of making and using such appliances. One method for forming a dental appliance includes forming a liquid thermoset polymer material into a semi-solid first shape, thermoforming the semi-solid first shape of thermoset polymer material onto a dentition mold, and curing the thermoset polymer on the dentition mold with a curative trigger to complete a molecular cross-linking reaction.

A method and apparatus for performing an assembly operation. A tool may be macro-positioned within an interior of a fuselage assembly. The tool may be micro-positioned relative to a particular location on a panel of the fuselage assembly. An assembly operation may be performed at the particular location on the panel using the tool.

A method for manufacturing shaped polymers of surface-active macromolecules, in particular silk, is provided. The method is comprising the steps of: a) depositing an aqueous solution of the surface-active macromolecules on a surface, wherein the aqueous solution of the surface-active macromolecules is deposited in the form of a droplet, and wherein the surface is a hydrophobic micropatterned surface adapted to prevent the aqueous solution from penetrating into the pattern and to receive the droplet of the aqueous solution of the surface-active macromolecules and retain its droplet state; and b) forming shaped polymers of the surface-active macromolecules on the surface.

The invention relates to a process for forming a pre-defined recess in a cured or cast explosive composition comprising the steps of: i) providing a female mould, ii) providing a male former, and locating said male former proximate to the female mould to create a gap between said male former and female mould, iii) forming an admixture of a curable/castable explosive composition, charging the gap with the admixture of explosive composition, causing the cure or cast of said curable/castable explosive composition, removing the male former to furnish a cured or cast explosive composition with a pre-defined recess.

A structure with improved adhesion includes projections and a backing layer, the rigidity of the backing layer being variable, and the end faces defining a common surface.

The present invention provides a microneedle array, a support member, a method of producing a microneedle array, and a microneedle array unit which enable reduction of a drying time during production and prevention of breakage during drying.

Provided are a microneedle array 120 including a sheet portion 41, a plurality of needle-like protrusions 44, and a support member 50 formed of a gripping portion 52 and a beam portion 54 having one end that is connected to the gripping portion 52, in which the sheet portion 41 is an integrally molded body which is integrally molded with the support member 50, in which at least a part of the beam portion 54 is buried under the other surface 43 of the sheet portion 41, opposite to the one surface where the needle-like protrusions 44 are provided, the gripping portion 52 is provided on the other surface 43 of the sheet portion 41, and the beam portion 54 is deformable toward a center of the sheet portion 41. Further, provided are the support member 50, a method of producing the microneedle array 120, and a microneedle array unit 300 including a container 310.

The present invention includes producing a preliminary mold (10-1 or 20-1) provided with two-dimensional patterns (111 or 211) having a shape of a microneedle array (30) therein; producing microneedle array molds (10 and 10-2 or 20 and 20-2) having a three-dimensional shape by expanding air inside the patterns (111 or 211) having a two-dimensional shape to deform the patterns (111 or 211) having the two-dimensional shape into molds having the three-dimensional shape; and after pouring a biodegradable resin into the microneedle array molds (10 and 10-2 or 20 and 20-2) and solidifying the biodegradable resin, completing the microneedle array (30) by removing the microneedle array molds (10 and 10-2 or 20 and 20-2), thereby providing a mold for production of a microneedle array and a production method of the microneedle array using the same capable of tightly suturing an affected area without inducing pain.

A resin molded article is equipped with a resin base material layer, a cover layer, and a design layer. The design layer is provided on a design side end surface of the resin base material layer, whereas the cover layer is provided on a cover side end surface which is a rear surface of the design side end surface. Further, the cover layer includes a first end surface facing toward the cover side end surface, and a second end surface which is a rear surface of the first end surface. The first end surface is covered by a first coating layer, and the second end surface is covered by a second coating layer.

A method of manufacturing a cover layer for a vehicle interior component includes forming a mold cavity via a first surface and a second surface spaced apart from one another by a distance. The first surface is configured to form a show surface of the cover layer, the second surface is configured to form a rear surface of the cover layer, and the distance is less than or equal to 1 mm. The method of manufacturing the cover layer also includes heating the first surface and/or the second surface, and flowing liquid polyvinyl chloride into the mold cavity to form the cover layer.

A simulated abdominal wall model that is ideal for practicing laparoscopic first entry surgical techniques is provided. The model includes a simulated abdominal wall portion captured between two frame elements of a support. The support is connectable to a surgical trainer. When connected to the trainer, the model provides a penetrable abdominal tissue portion for accessing an internal cavity of the trainer. The simulated abdominal wall includes a plurality of layers including a skin layer, a fabric posterior rectus sheath layer, a simulated fat layer of low-resilience polyurethane foam and at least two layers that provide distinctive haptic feedback upon penetration of the simulated transversalis fascia and muscle layers. The simulated abdominal wall includes a simulated umbilicus across several layers of simulated tissue.