A delivery device is provided which comprises a container containing a dose of a powder and having at least one exit orifice for dispensing the dose from the container and a chamber adapted to receive the container in an operative configuration. The device further comprises at least one gas inlet by which gas may enter the chamber and at least one gas outlet by which gas and entrained powder may exit the chamber. The delivery device is operable to generate a gas flow through the chamber between the at least one gas inlet and the at least one gas outlet, which brings about orbital motion of the container within the chamber in that at least a central region of the container orbits a central axis of the chamber. The volume occupied by the container is at least 25% of the volume of the chamber.

There is described a dry powder medicament delivery device comprising: a medicament container containing a unit dose of dry powder medicament; a medicament dispensing assembly; and optionally an air source.

A receptacle section for an aerosol provision article, arranged for receiving an element for modifying a property of aerosol passing through said element received in the receptacle section in use. The receptacle section having a configuration defining a flow path for said aerosol to flow through the receptacle section. The receptacle section including a first portion and a second portion moveable, the second portion being slidably mounted to the first portion. The receptacle section being arranged to allow at least one of insertion or removal of the element into or from the receptacle section in a direction substantially perpendicular to the longitudinal axis of the receptacle section.

A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin, oxyntomodulin and glucagon-like peptide.

A powder aerosolization apparatus comprises a housing comprising an outlet adapted to be inserted into a user's mouth and one or more bypass air openings. A receptacle support within the housing supports a receptacle containing a powder pharmaceutical formulation. A puncturing mechanism within the housing creates in the receptacle one or more inlet openings and one or more powder outflow openings, wherein the powder outflow openings have a total area of from 0.2 mm.sup.2 to 4.0 mm.sup.2. Upon a user's inhalation through the outlet, air flows through the one or more bypass air openings and through the receptacle to aerosolize the powder pharmaceutical formulation in the receptacle. In one version, the relative flow parameters between the flow through the one or more bypass openings and the one or more powder outflow openings are selected so that flow of aerosolized pharmaceutical formulation does not occur until a predetermined inhalation flow rate is achieved.

A sheet-type aerosol generating article includes at least two aerosol generating sheets each having aerosol generating material and an inductively heatable susceptor The inductively heatable susceptor is positioned between the aerosol generating sheets and each of the aerosol generating sheets has an exposed surface. Methods for manufacturing sheet-type aerosol generating articles are also disclosed.

This cartridge is provided with a flavor source housing which houses a flavor source, and a mesh body which is arranged on at least one end of the flavor source housing. The mesh body has multiple openings. Each of the openings has a polygonal shape with interior angles of less than or equal to 180°. As lengths that pass through the center of gravity of each opening, each opening has a minimum length that is shortest and a maximum length that is longest. The minimum length is less than the smallest size of the raw material pieces, and the maximum length is greater than the minimum length.

A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and peptides being administered to a patient in need of treatment. In particular, the drug delivery system is designed for inhalation for delivery of drugs to the pulmonary circulation in a rapid and therapeutically effective manner.

A capsule for use with an electronic smoking device includes a shell (105) having a lateral wall (101, 102) and an end wall (103), wherein the lateral wall (101, 102) and the end wall (103) defines a cavity (110) open at one end (111). A puncturable membrane (104) seals the open end (111) of the cavity (110). A liquid is contained within the cavity (110) by the shell (105) and the puncturable membrane (104), wherein a liquid transporting element (120) is arranged within the cavity (110) enclosed by the puncturable membrane (104) and immersed in the liquid.

A nasal fluid dispenser device comprising: a body (10) comprising a hollow sleeve (11) and a top surface (15); and an actuator member (40) that is mounted to slide in said body (10) so as to actuate the device; the device further comprising two nasal extensions (20, 30), at least one of which forms a dispenser head provided with a respective dispenser orifice (21, 31), said nasal extensions extending from said top surface (15), each dispenser head being connected, during actuation, to a respective reservoir (50) that is arranged in said body (10), said two nasal extensions (20, 30) forming an angle lying in the range 30° to 60° relative to a longitudinal central axis (A) of said body (10).