The methods described herein provide improvements to the measurement of dose content uniformity of inhaler and nasal devices. The methods involve analyzing and measuring a spray pattern of an emitted spray from an inhaler or nasal device. The spray pattern may be used to determine the dose content uniformity of an inhaler or nasal device.

A counter for a handheld device for dispensing a pharmaceutical substance, has a housing, at least one counter wheel which has readable characters, and a drive part which is designed to rotate the counter wheel, the counter wheel being rotatably attached to a mounting part. The mounting part of the counter is designed independently of the housing, and the drive part is directly attached to the mounting part. The counter can have at least one counter wheel which has readable characters and a drive part which is designed to rotate the counter wheel. The counter wheel has readable characters and is designed in a cylindrical manner and with a central axis, and has a drive part which is designed to rotate the counter wheel, the counter wheel being provided with an engagement toothing via which the drive part acts on the counter wheel so as to rotate same, the drive part having a rotational axis.

The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

A nebulizer is proposed which comprises a replaceable container containing fluid, a housing part detachable from the nebulizer for replacing the container, and an operation counter inseparable from the housing part as depicted in exemplary FIG. 10. The operation counter comprises a lead screw and an associated rider both supported by the housing part.

Disclosed is a hand piece for an aesthetic and medical device including a first body portion having a cylindrical structure in which a cartridge mounting space a second body portion bound to a lower side of the first body portion and having a cylindrical structure having an upper side on which an air pressure providing portion configured to provide air pressure to the cartridge-mounting space and the auxiliary air flow paths is mounted and a spray head portion bound to an upper body of the first body portion and having a central part on which a spray needle bound to an upper body of the cartridge to upwardly spray the liquid cosmetic product or liquid medication accommodated in the cartridge is mounted.

Methods and vaporizer apparatuses that estimate, measure and/or predict the amount of vapor and/or material (including active ingredients) released by the vaporizer apparatus. In particular, described herein are electronic vaporizers and methods of using them that determine a dose/amount of vapor and/or a material in the vapor based primarily or exclusively on the electrical and thermal properties, e.g., power or energy applied to the vaporizing element (e.g., heating coil) and the temperature of the material immediately before and as it is vaporized. Dose information may be used to control operation of the device and/or reported to the user.

A method for estimating an inhale dose when a drug is delivered to a person using an inhaler is disclosed. A predicted inhale dose (PID) of the drug is estimated based on at least one first-type parameter and at least one second-type parameter. The first-type parameter is related to a breath pattern of the person, and the second-type parameter is related to the inhaler.

This invention provides a dosage form dispenser, comprising a casing comprising a first portion adapted for insertion within an oral cavity of a subject and a second portion adapted to encase a dosage form dispensing mechanism located therewithin; at least one camera positioned on said second portion of said casing, further positioned to capture a field of view of a portion of a face of a subject, wherein said field of view comprises at least a portion of a base view of the nose of said subject; a dosage form dispensing mechanism; a microprocessor and associated memory for processing and storing user authentication information, comparing images relayed from said at least one camera to at least one stored user standard and providing authentication when a match is established; and an interface connected to said dispensing mechanism, which promotes dispensing said dosage form when said authentication has been obtained. Methods for dispensing a dosage form directly within an oral cavity of a subject in need thereof, using the dispensers are also described.

At least one example embodiment discloses a pod for an electronic vapor (e-vapor) apparatus. The pod includes a pre-vapor formulation compartment configured to hold a pre-vapor formulation therein, a device compartment in fluidic communication with the pre-vapor formulation compartment, the device compartment including a processor configured to monitor the pre-vapor formulation compartment and identify the pre-vapor formulation and a vapor channel extending from the device compartment and through the pre-vapor formulation compartment.

A fluid dynamic valve passively allows fluid flow out of a moving stream in one flow direction and not in the reverse. This allows the collection of fluid from a single direction of an AC fluid flow. The siphoned portion of the flow has a flow rate proportional to the mainstream flow. This device can collect exhaled breath or selective entrenchment during inhale. In one orientation, it can meter aerosolized particles into an inhale breath stream for pulmonary delivery, without complicated breath timing or drug loss due to drug adsorption to the back of the throat. Alternatively, a user can breathe through the device and a proportional amount, relative to the volumetric flow rate, of each exhale can flow into an auxiliary chamber for analysis. In addition, the device has a low respiratory burden and is comfortable to use.