A compliance monitoring module for an inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being configured to be pneumatically coupled to a flow channel of said inhaler through which a user can inhale; a processor configured to: receive data from a sensing element of the pressure sensor; receive data from a mode sensor configured to detect when the inhaler changes from an inactive mode to an active mode; and based on said data from said pressure sensor sensing element and said data from said mode sensor, compile a compliance report; and a transmitter configured to issue said compliance report.

A method and a wash, clean and dry system are provided for washing, cleaning and drying a surface region of a human body. The system includes a toilet seat assembly with a bidet assembly having a spray canister device for spraying the surface region with a solution, such as a skin protecting barrier solution, a cleaning solution or a medicated solution. In one aspect, the spray canister device can be movably insert into and out of the toilet seat assembly and is easy to operate and use. In addition, the bidet assembly further includes a spray nozzle assembly and a drying nozzle assembly, which are adapted to wash, clean and dry the region of the human body in three dimensional moments. The removable spray canister device with the removable sleeved cover element is thus easy to carry and be re-filled with new solutions.

A tensioning arrangement for an aerosol dispenser is presented where the tensioning arrangement has a conveying tube; an elastic member arranged to store mechanical energy from a substantially axial tensioning movement of the conveying tube; a rotatable member; a transmission mechanism configured to transmit a tensioning rotation of the rotatable member to the tensioning movement of the conveying tube, wherein the transmission mechanism has a cam profile and a cam follower arranged to follow the cam profile, wherein the cam profile has at least one priming structure; and wherein the tensioning arrangement is configured such that the conveying tube makes a temporary priming movement towards an initial position when the cam follower passes each priming structure during the tensioning movement of the conveying tube by means of the tensioning rotation of the rotatable member. An aerosol dispenser is also provided.

Actuators for a pressurised metered dose inhalers containing (a) a housing adapted to receive an aerosol canister containing a pressurised medicament formulation, (b) a nozzle block defining the receptacle for the aerosol canister valve stem, the expansion chamber or sump, the nozzle channel its external aperture, and (c) a mouthpiece portion comprising a central rounded opening of a defined width and distance from the nozzle aperture and a cylindrical recess, whose central axis is aligned with the central longitudinal axis of the mouthpiece portion and with the central longitudinal axis of the nozzle channel, provide a significant reduction in the non-respirable coarse fraction of the emitted aerosol medicament via inertial impaction and retention in the actuator rather than in the oro-pharynx, with consequent less associated side effects and oral candidiasis in the patient. In addition, the presence of the central rounded opening has minimal, negligible impact on the fine particle dose of the delivered aerosol particles.

An example accessory for an inhaler includes: a housing to couple to the inhaler; an accelerometer disposed in the housing, the accelerometer to obtain (i) motion data representing motion of the inhaler and (ii) orientation data representing an orientation of the inhaler; a microphone disposed in the housing, the microphone to obtain audio data for determining an inhalation rate of a user of the inhaler; a force sensor disposed in the housing, the force sensor to obtain force data representing force applied to the accessory; a communications interface disposed in the housing; a memory disposed in the housing; and a processor disposed in the housing, the processor interconnected with the communications interface and the memory the processor to: detect actuation of the inhaler based on the force data applied to the accessory; and generate dosage administration data based on the motion data, the orientation data and the audio data.

An inhalant dispensing system is provided, comprising an inhalant delivery apparatus having a main body, a lower body coupled to the main body and comprising a mouthpiece, and an inhalant delivery mechanism disposed within the main body and configured to deliver an aerosolized solution to the mouthpiece for user inhalation; and a lock out system configured to selectively prevent delivery of the aerosolized solution to the mouthpiece. The inhalant delivery apparatus may be assembled by inserting a portion of the inhalant delivery mechanism into the main body. The lower body may be rotatably coupled to the main body and moveable between a dispensing position and a storage position. The system may be used to control and monitor dosages of a solution contained within a smart canister and administered from the canister via an inhaler, to prevent accidental or unwanted usage of the canister and/or over-dosing.

A fluid dispenser comprising a body (1), a fluid reservoir (2), a dispenser member, such as a pump or a valve, mounted on said reservoir (2), and a dose indicator device for indicating the number of doses of fluid that have been dispensed or that remain to be dispensed from said reservoir, the dispenser being characterized in that said dose indicator device includes a first safety system for actuating the dose indicator device once the dispenser has performed a predetermined incomplete actuation stroke, even if the dispenser does not perform the complete actuation stroke.

An inhaler includes a mouth-piece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.

The present invention provides a spacer device having a flow rate spirometer. The flow rate indicator allows users to use a measured, consistent flow rate leading to improved synchronicity and actuation.

Various methods and devices of treating infectious diseases are described. In one example embodiment, a method of treating an infectious disease in an individual in need thereof is provided, including administering a therapeutic agent to the individual and electroporating a tissue of the individual, wherein the therapeutic agent is inhalable.