A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.

A method of extruding filament comprises the steps of cutting a bulk source material into pieces having size S.sub.1, performing a first extrusion pass comprising the steps of melting the pieces in an extruding device at a temperature T.sub.1 and extruding a first filament at an extrusion speed V.sub.1, and performing at least one additional extrusion pass k comprising the steps of cutting the first filament into pieces having size S.sub.k, melting the pieces in an extruding device at temperature T.sub.k, and extruding a final filament at an extrusion speed V.sub.k. A system for extruding filament is also described.

A catheter assembly is constructed by reflow bonding an inner liner and an outer layer. The inner liner defines at least one lumen. The inner liner is made of a gamma-irradiated polymeric material that includes a polyether block amide and a gamma radiation activated cross-linking agent.

Provided is a three-dimensional modeling material used for a fused deposition modeling three-dimensional printer. The three-dimensional modeling material has a multilayer structure and contains, in respective different layers, a thermoplastic resin (A) having a shear storage elastic modulus (G′) of 1.00×10.sup.7 Pa or less as measured at 100° C. and 1 Hz and a thermoplastic resin (B) having a shear storage elastic modulus (G′) of more than 1.00×10.sup.7 Pa as measured at 100° C. and 1 Hz.

A regenerated cellulosic molded body of cellulose and at least a part of at least one foreign matter, and is produced by supplying a starting material which comprises cellulose and at least one foreign matter, transferring at least a part of the starting material with at least a part of the at least one foreign matter into a spinning mass which additionally contains a solvent for solving at least a part of the cellulose of the starting material in the solvent, and extruding the spinning mass to the molded body, and subsequently precipitating in a spinning bath.

A regenerated cellulosic molded body of cellulose and at least a part of at least one foreign matter, and is produced by supplying a starting material which comprises cellulose and at least one foreign matter, transferring at least a part of the starting material with at least a part of the at least one foreign matter into a spinning mass which additionally contains a solvent for solving at least a part of the cellulose of the starting material in the solvent, and extruding the spinning mass to the molded body, and subsequently precipitating in a spinning bath.

Apparatus 2 for dosing a liquid colour formulation into polymer includes a weighing platform 4 which is supported on a pair of load cells 6 which are, in turn, supported on a base 8. A reservoir 12 contains liquid colour formulation 14. A pump 16 is arranged to pump liquid formulation, via a tube 20, to an extruder or injection moulding machine. Above inlet 24 is a delivery pack 26 which includes a bag-in-a-box arrangement 28. The delivery pack 26 includes a transfer pump 36 associated with an outlet of the receptacle 32. A transfer pump motor 38 is arranged to be engaged with the transfer pump 36 and operated so that liquid formulation can be pumped from the receptacle 32 into reservoir 12 across an air gap 13 defined between the transfer pump 36 and the inlet 24 of reservoir 12. There is no pipe, tube or other conduit through which liquid formulation passes on travel between delivery pack 26 and reservoir 12.

A valve having a valve housing and a blocking element, wherein the valve housing has a hollow space for receiving the blocking element, an inlet opening for allowing a fluid to flow into the hollow space and an outlet opening for allowing the fluid to flow out of the hollow space, wherein the blocking element has a guide body and is arranged linearly moveably and at least partially in the hollow space of the valve housing between the inlet opening and the outlet opening, wherein the blocking element has at least one opening for allowing the fluid to flow from the inlet opening to the outlet opening via the opening.

A valve having a valve housing and a blocking element, wherein the valve housing has a hollow space for receiving the blocking element, an inlet opening for allowing a fluid to flow into the hollow space and an outlet opening for allowing the fluid to flow out of the hollow space, wherein the blocking element has a guide body and is arranged linearly moveably and at least partially in the hollow space of the valve housing between the inlet opening and the outlet opening, wherein the blocking element has at least one opening for allowing the fluid to flow from the inlet opening to the outlet opening via the opening.

A thermal sensor wire. The thermal sensor wire may include a thermal sensing portion extending along a wire axis of the thermal sensor wire; and a carrier portion, the carrier portion extending along the wire axis, adjacent to the thermal sensing portion, the thermal sensing portion comprising a polymer positive temperature coefficient (PPTC) material or a negative temperature coefficient (NTC) material.