A transdermal delivery system for delivery of a triptan into a tissue membrane of a subject. The system includes a transdermal microporation apparatus for heating a skin surface and a triptan drug delivery patch. The drug delivery patch comprises a top layer comprising an adhesive, a middle layer comprising the triptan, and a bottom layer. A method for treating a subject comprises identifying a subject having a migraine, using the transdermal microporation apparatus to open a plurality of micropores in the skin of the subject, and applying the triptan drug delivery patch to the subject's skin over the micropores for a period of time effective to deliver the triptan through the micropores in an amount effective to treat the subject's migraine.

Embodiments of the present invention are directed to devices and apparatus for administering collagen modifier compounds to the dermis of skin.

A light therapy device used for a negative-pressure cup is provided. The light therapy device includes a carrier, a light therapy assembly, a negative ion assembly and a needle protection cap. The carrier is disposed in the negative-pressure cup and includes a panel. The light therapy assembly and the negative ion assembly are disposed in the carrier. The negative ion assembly includes a releasing needle. The releasing needle projects out from the panel to release negative ions. The needle protection cap covers the panel corresponding to the releasing needle to shield the releasing needle. Therefore, the light therapy assembly and the negative ion assembly may be associated with the negative-pressure cup for usage, and the needle protection cap may prevent the user from being stabbed.

The present invention is related to a pulse photodynamic therapy (or pulse PDT) treatment of photodamaged skin.

Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

A method for laser assisted delivery of therapeutic agents includes selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle, applying, through the first channel, a first substance to penetrate dermis to a predetermined depth, and administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.

Exemplary systems and methods associated with trans-tissue substance delivery using non-thermal plasma to porate skin or tissues using contoured dielectrics/electrodes and grounding techniques. In some embodiments, a substance delivery system may be incorporated into the plasma generating device for automatically controlled skin treatments. In other embodiments, a skin treatment patch may include the electrode and the treatment substance.

A transdermal delivery system: a delivery device; a band configured to connect the delivery device to a body part of a user, the delivery device comprising: a delivery chamber that is configured to receive a substance and a heating chamber configured to heat the substance in the delivery chamber so that the substance is liquified, vaporized, or both and exits the delivery chamber into contact with the body part of the user so that the substance is transdermally absorbed.

A micro-dosing oil dispenser with the ability to dispense multiple doses after the user rapidly depresses a dispensing button. The oil dispenser may vibrate upon completion of the doses. The oil dispenser may have a felt tip for better absorption.

The present disclosure relates to a medicament delivery devicecomprising at least one microneedle for delivering a medicament to a patient, and a system configured to enhance the penetration of the medicament into skin of the patient.