A nasal prong comprising a tube configured to be partially placed in a nasal passage of a patient, the tube having a first end, a second end, and an intermediate portion, and a lumen extending therebetween. The first end having an elongated opening configured to face supero-medially within the nasal passage, wherein airflow out of the elongated opening is directed superiorly and posteriorly within the nasal cavity, above the inferior concha, around the middle concha, and towards the roof of the nose. The intermediate portion of the tube having a bend that keeps the nasal prong on a floor of the nasal passage at and/or near the outer edge of a nostril.

A nasal prong comprising a tube configured to be partially placed in a nasal passage of a patient, the tube having a first end, a second end, and an intermediate portion, and a lumen extending therebetween. The first end having an elongated opening configured to face supero-medially within the nasal passage, wherein airflow out of the elongated opening is directed superiorly and posteriorly within the nasal cavity, above the inferior concha, around the middle concha, and towards the roof of the nose. The intermediate portion of the tube having a bend that keeps the nasal prong on a floor of the nasal passage at and/or near the outer edge of a nostril.

The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

A dry powder aerosol delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The dry powder aerosol delivery device includes a housing, a cartridge, and a dry powder dispersion mechanism, and at least one differential pressure sensor. The dry powder delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The dry powder aerosol delivery device is then actuated to generate a plume of particles having an average ejected particle diameter within the respirable size range, e.g., less than about 5-6 μm, so as to target the pulmonary system of the user.

A dry powder aerosol delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The dry powder aerosol delivery device includes a housing, a cartridge, and a dry powder dispersion mechanism, and at least one differential pressure sensor. The dry powder delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The dry powder aerosol delivery device is then actuated to generate a plume of particles having an average ejected particle diameter within the respirable size range, e.g., less than about 5-6 μm, so as to target the pulmonary system of the user.

Disclosed herein are facially fitting devices, such as nasal cannulas and oxygen masks, including illuminating placement marker(s), which facilitate correct placement of the facially fitting devices on a face of a subject in dark conditions. The placement marker is powered by a thermo-electric generator, which generates electrical power via thermal coupling thereof to skin on the face of a subject when the facially fitting device is fitted, or partially fitted, on the face of the subject.

Disclosed herein are facially fitting devices, such as nasal cannulas and oxygen masks, including illuminating placement marker(s), which facilitate correct placement of the facially fitting devices on a face of a subject in dark conditions. The placement marker is powered by a thermo-electric generator, which generates electrical power via thermal coupling thereof to skin on the face of a subject when the facially fitting device is fitted, or partially fitted, on the face of the subject.

A positioning and stabilising structure for a full-face mask of a patient interface comprises a superior strap portion, an inferior strap portion, and two anterior strap portions. Each anterior strap portion having a generally triangular surface with a first width and a second width that is less than the first width and disposed more anterior while in use. The superior strap portion and the inferior strap portion are each connected to or formed integrally with each anterior strap portion at a respective corner of the generally triangular surface. Each anterior strap portion is connected or connectable to a connection portion that engages the plenum chamber. The connection portion is releasably engageable from the plenum chamber. The superior strap portion and the inferior strap portion are joined to the anterior strap portions anterior to the patient's ears, when in use.

A positioning and stabilising structure for a full-face mask of a patient interface comprises a superior strap portion, an inferior strap portion, and two anterior strap portions. Each anterior strap portion having a generally triangular surface with a first width and a second width that is less than the first width and disposed more anterior while in use. The superior strap portion and the inferior strap portion are each connected to or formed integrally with each anterior strap portion at a respective corner of the generally triangular surface. Each anterior strap portion is connected or connectable to a connection portion that engages the plenum chamber. The connection portion is releasably engageable from the plenum chamber. The superior strap portion and the inferior strap portion are joined to the anterior strap portions anterior to the patient's ears, when in use.