A breath actuated metered dose inhaler may include a canister fire system configured to fire a medicament containing canister in response to patient inhalation. The canister fire system may include a pneumatic force holding unit and having a rest configuration in which a metering valve of the canister is in a refill configuration; a prepared configuration in which a canister actuation force is retained by the pneumatic force holding unit and the canister fire system is actuatable by patient inhalation induced airflow; and a fire configuration in which the metering valve is in a dose delivery position. When in the prepared configuration, the force retained by the so pneumatic force holding unit may be reduced by less than about 6% over a period of 5 minutes, preferably less than about 3% over a period of 5 minutes.

A method of augmenting or reconstructing a breast of a patient includes providing an implantable member and implanting the implantable member. The implantable member includes an exterior surface defined by an anterior face and a posterior face, wherein one of the anterior face and the posterior face includes at least one fixation region defined by a texture, roughness or sheen different from a respective texture, roughness or sheen of a balance of said one of the anterior face and posterior face. The implantable member is implanted into a breast of a patient such that the fixation region of the implantable member generally aligns with the pectoralis major muscle group or the pectoralis minor muscle group.

A polyurethane foam backing suitable for making a coated abrasive article is disclosed. The polyurethane foam backing has a textured surface bearing an array of raised features and land areas. The array's geometry is designed such that a 90 degree peel force to remove a production tooling having a contacting surface bearing a plurality of microreplicated mold cavities from the textured surface is accept able.

A soft prosthetic implant shell, such as a silicone breast implant shell, that has discrete fixation surfaces thereon for tissue adhesion. The fixation surfaces may be provided on the posterior face of the shell, as well as either on the periphery or at discrete areas on the anterior face. Band-shaped fixation surfaces may be provided on the anterior face of the shell to generally match the angle of pectoralis major or pectoralis minor muscle groups. The fixation surfaces may be roughened areas of the shell, or may be separate elements adhered to the shell.

In at least one embodiment of the present invention a balloon catheter is provided. The balloon catheter comprises a shaft having a lumen formed therethrough. Connected to the shaft is an inflatable balloon. The inflatable balloon has a balloon wall defining a balloon interior surface and a balloon exterior surface that is opposite the interior surface. In fluid communication with the balloon wall is the lumen for inflating the balloon to define an inflated state and for collapsing the balloon to define a deflated state. The balloon wall is textured in the deflated state such that the balloon interior surface is spatially registered with the balloon exterior surface. The balloon in the inflated state is tensioned to have a surface roughness substantially less than a surface roughness of the balloon in the deflated state.

A molded foam is provided in which even when a force in a sliding direction is applied to another member in contact with its surface, the occurrence of a shift in position relative to the other member can effectively be prevented and the occurrence of unusual noise due to rubbing between its surface and the other member can effectively be prevented. The molded foam is formed by heating expandable resin particles filled into a foaming mold. The molded foam has a plurality of first ridges arranged in one direction and a plurality of second ridges arranged in another direction and disposed so as to intersect the first ridges, the first and second ridges being provided on the surface of the molded foam.

A method of augmenting or reconstructing a breast of a patient includes providing an implantable member and implanting the implantable member. The implantable member includes an exterior surface defined by an anterior face and a posterior face, wherein one of the anterior face and the posterior face includes at least one fixation region defined by a texture, roughness or sheen different from a respective texture, roughness or sheen of a balance of said one of the anterior face and posterior face. The implantable member is implanted into a breast of a patient such that the fixation region of the implantable member generally aligns with the pectoralis major muscle group or the pectoralis minor muscle group.

The invention relates to a hot runner device comprising at least one needle valve nozzle and a shut-off needle which is movable in the needle valve nozzle by means of a movement means, and comprising an overload protection device for the shut-off needle, characterized in that the overload protection device is implemented as follows: the shut-off needle is connected in at least a first movement direction directly or indirectly to the movement means by at least one frictional connection that can be released when a threshold force is exceeded.

A transfer film (1), in particular for decorating casing components for motor vehicles or domestic appliances, including a carrier ply (3) with at least one carrier layer (31) and a transfer ply (2) arranged on the carrier ply (3), wherein the transfer ply (2) has a protective layer composite (21) having a first protective layer (5) and at least one receiving layer (4) for coating the transfer ply (2) in a coatable region (41) with at least one coating (6), wherein the at least one receiving layer (4) is arranged on the first protective layer (5) and wherein the at least one receiving layer (4) is arranged against a first surface of the transfer ply (2) facing towards the carrier ply (3). A a method for producing a transfer film, as well as a component and a method for the production thereof using a transfer film.

The invention provides a biaxially oriented polyester film, which exhibits excellent transparency, is easily subjected to secondary processing, is an environmentally friendly polyester film, and has little variations in physical properties in the machine direction, and a production method therefor. The biaxially oriented polyester film is formed of a polyester resin composition containing particles and 50% by weight or more of a polyester resin composed of biomass-derived ethylene glycol and fossil fuel-derived dicarboxylic acid units, wherein at least one surface of the biaxially oriented polyester film meets requirements (1) to (3): (1) a number of fine protrusions each having a height of less than 3 nm per area of 4?10.sup.?12 m.sup.2 is 250-600; (2) a number of fine protrusions each having a height of 3 nm or more per area of 4?10.sup.12 m.sup.2 is 300-600; and (3) an arithmetic mean height Sa is 0.010-0.025 ?m.