Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.

The invention relates to a surface structure and a Fresnel lens which has at least one such surface structure. Furthermore, the invention relates to a tool for production of a surface structure and a method for production of a surface structure or Fresnel lens. Furthermore, the invention relates to the use of a Fresnel lens.

Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.

Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.

The injection molding apparatus is provided for making highly accurate optical parts having structured reflective or deflecting optical surfaces. The apparatus includes a removable mold insert made of two or more mold insert segments. The mold insert segments are juxtaposed at mating lateral planar surfaces to form a reversed structured surface. The mold insert segments also includes a gas venting circuit having conduits formed when the mold insert segments are juxtaposed. A cooling circuit is provided in the mold insert segments.

Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.

A linear Fresnel lens sheet includes: a lens layer having a first surface in which a linear Fresnel lens portion, having a number of lens surfaces arranged in a first direction d1, is formed, and a second surface opposite the first surface; and a diffusion layer disposed on the side of the second surface of the lens layer.

A headset for virtual reality applications includes an optical element configured to modify light from an electronic display in the headset and to direct the modified light to a user. The optical element may include a Fresnel lens secured to a lens by securing the Fresnel lens to a mold and inserting a casting material into the mold so the casting material forms the lens and a portion of the casting material exists on and past an edge of the Fresnel lens. This encases the edge of the Fresnel lens in the casting material, securing the Fresnel lens to the lens.

Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.