An injector device comprising: an outer housing for receiving a medicament container; and a drive mechanism for dispensing medicament from a medicament container received in the outer housing. The drive mechanism comprises a plunger rod and a displacing member configured to displace a distal end of the plunger rod into said medicament container to dispense said medicament. The device further comprises a brake configured to slow the rate of displacement of the plunger rod under the force of the displacing member.

A patient interface includes a plenum chamber pressurisable to a therapeutic pressure, and a seal-forming structure constructed and arranged to seal with a region of a patient's face surrounding an entrance to a patients airways. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in the plenum chamber throughout a patients respiratory cycle in use. The patient interface also includes a positioning and stabilizing structure configured to hold the seal-forming structure in a therapeutically effective position on a patients head. The positioning and stabilizing structure includes a rear strap arranged to contact an occiput of the patients head. The rear strap is constructed from a first material is arranged to contact a temporal region of the patients head, and a second material arranged to contact the occiput of the patients head. The second material is silicone.

A male luer connector is provided that includes a luer slip having a first material, the luer slip sized and shaped to mate with a female connector. A collar is disposed on an outer surface of the luer slip, the collar having a second material and a plurality of first grip features disposed on an outer surface of the collar. A grip is coupled to the luer slip, the grip having a third material and a plurality of second grip features disposed on an outer surface of the grip, wherein one of the plurality of first and second grip features are configured to provide a slip resistant grip surface. Infusion sets and infusion set luer connector assemblies are also provided.

A blood filtration system can reduce the amount of plasma constituents (e.g., water and/or electrolytes) in the blood of the patient, and accordingly increase the hematocrit value of the patient. The blood filtration system (e.g., a controller, or the like) can determine a hematocrit value of a patient. The blood filtration system can determine a venous pressure of vasculature of a patient. The blood filtration system can compensate for pressure head in a component of a blood circuit (e.g., a withdrawal line of a catheter), for example to improve the accuracy of the venous pressure determination. The blood filtration system can determine one or more resistance characteristics of a blood circuit for the blood filtration system. The resistance characteristics can correspond to a resistance to a flow of blood through a component of the blood circuit.

Devices, kits and methods for determining the site of intramuscular injection in adult and child patients are disclosed. The device includes a top element and two legs that are configured to be fastened in a first position and a second position. When placed in the first position and second position, the device forms a substantially triangular region having a center that corresponds to the site of injection.

A patient interface includes a plenum chamber, a seal-forming structure, and a positioning and stabilising structure to provide a force to hold the seal-forming structure in a therapeutically effective position on a patient's head. The positioning and stabilizing structure includes a superior strap portion, an inferior strap portion, and a posterior connecting strap portion connected to or formed integrally with the superior strap portion and the inferior strap portion. The posterior connecting strap portion is constructed from a mesh material that is different than the material used to construct the superior strap portion and the inferior strap portion. The posterior connecting strap portion has a greater stretch capability than the superior strap portion and a lesser stretch capability than the inferior strap portion. The stretch capabilities allow the positioning and stabilizing structure to be removable from the patient's head when the loop engages the connection portion.

A catheter that includes a mechanism for deflecting a distal portion of a catheter may include a deflection knob including a first thread, a rod including a second thread that is coupled to the first thread, and a puller wire that is connected to the rod. The rod may additionally include a pocket to which the puller wire may be connected via a joining feature that may be secured in the pocket and attached to a proximal end of the puller wire. The joining feature may include a first ferrule joined, e.g., crimped, to the proximal end of the puller wire and a second ferrule secured, e.g., bonded, in the pocket and joined, e.g., crimped, to the first ferrule.

A patient interface comprises a seal-forming structure including a textile membrane and a support structure to support the textile membrane. The seal-forming structure may have a varying construction in order to accommodate different regions and the varying contours of the patients face to ensure a robust and comfortable seal. An air impermeable layer of the textile membrane may have a thickness that varies in different portions of the textile membrane and/or different regions of the cushion assembly. Further, the seal-forming structure may include an underlying cushion, and an arrangement of the textile membrane and the underlying cushion and/or the configuration of the underlying cushion may vary in different regions of the cushion assembly to optimize patient comfort and the effectiveness of the seal in different regions of the patients face.

A patient interface including a seal-forming structure having a mouth portion that forms at least part of the mouth plenum and is configured to seal around the patient's mouth and a nasal portion that is configured to seal with the patient's nares. The nasal portion includes a nasal plenum positioned to receive pressurized gas from the mouth plenum. The seal-forming structure also includes a clip configured to connect the mouth plenum to the nasal plenum and act as a conduit for the flow of the pressurized gas from the mouth plenum to the nasal plenum. The clip includes a mouth portion end configured to engage the mouth portion, a nasal portion end configured to engage the nasal portion, and a pair of wings protruding from the nasal portion end into an interior of the nasal plenum so that the wings engage an interior surface of the nasal plenum.

A patient interface to deliver air at a positive pressure to a patients airways, including nasal and mouth cushions; a positioning and stabilizing structure to provide a force to hold the nasal seal-forming structure or the nasal seal and the mouth seal-forming structure in position on a patients head, the positioning and stabilizing structure comprising nasal and oro-nasal headgear configurations and including left and right headgear sections, a pair of nasal headgear clips connecting the nasal headgear to the left and right headgear sections at a first angle and/or position applying nasal headgear forces to the nasal seal-forming structure, and a pair of oro-nasal headgear clips connecting the oro-nasal headgear to the left and right headgear sections at a second angle and/or position applying oro-nasal forces to the mouth seal forming structure in the oro-nasal configuration. The first angle and/or position is different than the second angle and/or position.