A flow sensor sub-assembly for sensing flow of a fluidic medicament includes a flow tube having a flow tube inlet and a flow tube outlet, and an acoustical transmission rate. The medicament flows through the flow tube. A first piezo element is arranged at an upstream position of the flow tube and a second piezo element is arranged at a downstream position of the flow tube, such that the first piezo element and the second piezo element are mounted apart a pre-selected distance from each other. An absorber sheath encircles the flow tube. The absorber sheath has an upstream end and a downstream end. The absorber sheath is comprised of a material with an acoustical transmission rate different than the flow tube.

Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.

The present invention is directed to improved methods, devices, and systems for eye surgery. In some embodiments, the invention may provide new and/or improved devices, systems, and methods for detecting surgical fluids in a fluidics cassette, particularly cassettes which are used to couple an eye treatment probe to an eye treatment console. Rather than relying on internal reflection by a gas-liquid interface, the fluid detection techniques described herein may make use of the changes in propagation of light through a portion of the holding tank when the portion varies between empty and full. Other aspects of the invention may provide devices, systems, and methods for producing different types of fluidics cassette using a single cassette body type.

The present invention relates to a concentrate container having a concentrate that is configured to form a dialysis solution after its dilution with a diluting agent, in particular with water, wherein the concentrate container is in communication with a first connector having a first code that contains at least one piece of information on the concentrate; and wherein the concentrate container is furthermore in communication with a second connector whose second code differs from the first code, with the second code containing at least one piece of information on the dialysis solution.

A method for operating a dialysis machine to conduct a dialysis treatment on a patient (e.g., a peritoneal dialysis machine) may include transferring dialysate from a first bag, and automatically determining the dialysate from the first bag has completely transferred. After determining the dialysate has completely transferred from the first bag, switching from the first bag to a second bag of dialysate. The method may further include transferring dialysate from the second bag in response to the detection of the completed transfer of the first bag, and automatically determining the dialysate from the second bag has completely transferred. The method may further include determining if the respective first or second bag has completely transferred by comparing a dialysate bag volume transferred to the patient to a detected volume of the respective first or second bag. Systems with dialysis machines for performing such a method are disclosed as well.

A medical infusion fluid handling system, such as an automated peritoneal dialysis system, may be arranged to de-cap and connect one or more lines (such as solution lines) with one or more spikes or other connection ports on a fluid handling cassette. This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines and the one or more spikes. For example, the automated peritoneal dialysis system may include a carriage arranged to receive the one or more lines each having a connector end and a cap. The carriage may move along a first direction so as to move the connector ends of the one or more lines along the first direction, and a cap stripper may be arranged to engage with the caps on the one or more lines on the carriage. The cap stripper may move in a second direction transverse to the first direction, as well as to move with the carriage along the first direction.

An extracorporeal blood treatment machine includes a blood treatment device, a conveying device for conveying blood through the blood treatment device, and a connection mask designed to interchangeably receive a tube set in a predefined arrangement. The tube set has pressure-monitoring lines that branch off from the tube set and can be connected to pressure sensor connections located on the connection mask. The pressure sensor connections are spaced apart and positioned so as to match the tube set such that, when the tube set is mounted in the predefined arrangement on the connection mask, each pressure-monitoring line, owing to its limited length and the predefined arrangement of the associated branch on the blood treatment machine, can be connected exclusively to only one of the pressure sensor connections. A corresponding tube set is used with the extracorporeal blood treatment machine.

Various fluid delivery systems are described comprising an infusion pump having a housing with a first opening and a hollow interior portion that is configured to receive a cartridge having a tubing. A pump unit can be disposed within the housing. The pump unit comprises a motor mechanically coupled with a crank shaft or eccentric cam that is configured to move a set of pistons or other objects to thereby compress one or more portions of the tubing over time as the crank shaft or eccentric cam rotates.

A pump set for use with a pumping apparatus includes tubing for carrying a liquid. A valve mechanism is mounted to the tubing between an inlet section and a pump engagement section. The valve mechanism includes a first port connected to the inlet section of the tubing, a second port connected to the pump engagement section of the tubing, and a valve disposed between the first and second ports. The valve includes a stem rotatably mounted within a stem holder. The stem includes a flow passage extending through the stem and having an open V shape whereby a narrow open end of the flow passage communicates with the first port and a wide open end of the flow passage communicates with the second port to place the inlet section of the tubing in communication with the pump engagement section of the tubing.

A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.