An inhalation device, assembly or system can include a kit and a pharmaceutical composition. The device can be adapted for administering therapeutic aerosols to pediatric patients, including neonates, infants or toddlers. The device can further include a vibrating mesh aerosol generator that can be insertable into a flow channel of the inhalation device through a lateral opening, and a valved face mask. The device can be connectable to a gas source through which a gas, such as oxygen, can be received into the flow channel at a low flow rate.

Methods are provided for the treatment of RSV infections in young children. More specifically, methods are provided wherein polypeptides that bind F protein of hRSV and that neutralize RSV infection are administered to the lungs of young children at specific dose regimens.

Described are nasal cannulas that improve the precision of the delivered dose for nitric oxide therapy by reducing the dilution of nitric oxide. The nasal cannulas may reduce the total volume and potential for retrograde flow during nitric oxide therapy through the design of the specific dimensions of the flow path and/or having check valves in the nitric oxide delivery line and/or having a flapper or umbrella valve dedicated to nitric oxide delivery. The nasal cannulas may also use materials that limit oxygen diffusion through the cannula walls. The nosepiece for these cannulas may be manufactured by a molding technique.

A tracheal connector is connected to a respiratory gas generator and a tracheal tube. The tracheal connector includes a tracheal connector body connected to the tracheal tube, a connector tube connected to the tracheal connector body and the respiratory gas generator, and a restriction mechanism configured to narrow a respiratory gas flow path configured to allow the respiratory gas to flow therein. The tracheal connector body includes a tracheal port connected to the tracheal tube, an exhaust port facing the tracheal port and configured to discharge at least expired air of the subject, and a respiratory port connected to the connector tube. The restriction mechanism is provided on the respiratory gas flow path between the respiratory port and the tracheal port.

A system for intra-operative blood salvage autotransfusion is provided. The system comprises at least one inlet configured to receive whole blood of a patient; at least one curvilinear microchannel in fluid flow connection with the at least one inlet, the at least one curvilinear microchannel being adapted to isolate circulating tumor cells in the whole blood, based on cell size, along at least one portion of a cross-section of the at least one curvilinear microchannel; and at least two outlets in fluid flow connection with the at least one curvilinear microchannel, at least one outlet of the at least two outlets being configured to flow the circulating tumor cells isolated from the whole blood, and at least one other outlet of the at least two outlets being configured to flow at least a portion of a remainder of the whole blood, cleansed of the isolated circulating tumor cells, for return to the patient.

A mask configured to assist the respiration of a patient with a gas inlet port positioned to connect a gas supply to the mask and direct gas flow towards a patient's skin; a scattering chamber with an inlet port and a plurality of outlet ports, the scattering chamber inlet port fluidly connected to the gas inlet port, and the plurality of outlet ports positioned to scatter the gas flow away from the patient's skin and towards the interior surface of the mask and a region between the patient's skin and the interior surface of the mask; and an outgas collector assembly connected adjacent the scattering chamber and positioned to collect an outgas emission expelled from the patient and eject the outgas emission from the mask.

A device includes a body defining a respiration passage in fluidic communication with a filter fitting disposed on a first end of the body and a mask fitting disposed on a second end of the body, and a treatment passage in fluidic communication with the mask fitting. A treatment fitting is disposed on the body and is coupleable to a treatment source such that a seal in the treatment fitting transitions from a closed state to an open state to allow fluidic communication between the treatment source and the treatment passage. The device configured to permit (i) inhalation air and/or exhaled breath to be drawn and/or expelled through the filter fitting, the respiration passage, and the mask fitting and (ii) a respiratory therapeutic to be drawn from the treatment source coupled to the treatment fitting, through the treatment passage, and through the mask fitting.

Methods and system for treating obstructive sleep apnea and snoring are disclosed. The system generally comprises a mask for delivering pressurized air to patient's breathing orifice, a sensing mechanism for continuously assessing the state of patient's breathing and a pressure generator for generating the pressurized air in the mask. The pressurized air is applied to the breathing orifice only during selected portions of the breathing cycle, when such pressure might be required to prevent occlusion of the airway or to restore patency of the airway after such occlusion occurs.

A nebulizer device and a nozzle module are provided. The nebulizer device includes a nebulizer module, the nozzle module, and a control module. The nozzle module includes a main body unit and a guide unit. The main body unit can be detachably connected to the nebulizer module. The main body unit has a plurality of openings penetratingly formed therethrough, an accommodating space, and an output part, and the openings and the output part are in spatial communication with the accommodating space. The main body unit corresponds to an inner wall of the accommodating space and protrudes toward the accommodating space to form a plurality of guiding parts, and each of the guiding parts is adjacent to one of the openings. The guide unit is disposed in the accommodating space and has a recessed part. The control module can be detachably connected to the main body unit.

The method including first establishing a first airflow in a first passage of an e-vaping cartridge, the first passage including a first portion, a second portion and a third portion, a first air inlet in communication with the first portion, a heater in communication with the second portion, the second portion being between the first portion and the third portion, and second establishing a second airflow in a second passage of the e-vaping cartridge, the second passage being in communication with the third portion.