A method and apparatus are disclosed for forming a drug coating layer capable of preventing breakage of elongated drug crystals on a surface of a balloon and maintaining the drug crystals in an appropriate shape in order to act on a living body. The method includes supplying a coating solution which contains the water-insoluble drug, a water-soluble additive, an organic solvent, and water to the surface of the balloon and evaporating the organic solvent and the water to form an additive layer containing the water-soluble additive and a protruding crystal having a tip end protruding from the additive layer, cutting a surplus portion protruding from the additive layer of the protruding crystal from a part surrounded by the additive layer and forming the part surrounded by the additive layer as the elongated body, and removing the cut-out surplus portion from the drug coating layer.

A dispensing outlet includes a housing with a first end of the housing having a first outlet and a second end of the housing having a mixing or reception space. The mixing or reception space is configured to receive a further component, and a pre-determined breaking point is formed between the first outlet and the mixing or reception space.

A rigid needle guard (10) comprising an inner part (11) made of elastomeric material, and a rigid outer body (12) that is fastened to said inner part (11) made of elastomeric material via a folded-in portion (121) of the bottom axial end of said rigid outer body (12), said folded-in portion (121) extending radially inwards from the outer peripheral surface (125) of said rigid outer body (12), the outer surface of said folded-in portion (121) forming, at its axially-bottom and radially-outer edge, a sharp and acute angle relative to the outer peripheral surface (125) of said rigid outer body (12).

A device for translaminating tension-sensitive films from a first liner to a second liner, wherein the device has a first transport device, a second transport device, and a laminating device. The first transport device is configured to transport a first laminated strip to a film delaminating station. The second transport device is configured to transport a second strip-shaped liner to the laminating device, which is designed to laminate the tension-sensitive film onto the second liner in order to form a second laminated strip. The first transport device and the laminating device are arranged relative to each other such that the tension-sensitive film is pulled off at the film delaminating station in the direction opposite the running direction of the first laminated strip at said station.

Systems and methods for manufacturing an elongate medical device including various surface features. The system including a heating cartridge, a heating element, a filament handling system, a substrate handling system, a controller, and one or more additional components adapted to form the surface features on the medical device. The heating element melts a filament material within the heating cartridge to form a jacket of the medical device and the one or more additional components engages the outer surface of the jacket to create surface features.

Welded headgear sections can be produced by using a weld tool having pins protruding from a weld region contact surface to deliver high-frequency electromagnetic energy to a weld region defined by overlapping top and bottom headgear straps. The pins fully penetrate the top strap and at least partially penetrate the bottom strap. The pins concentrate the electromagnetic energy to achieve a weld joint of acceptable weld strength and aesthetic appeal.

The equipping of syringe barrels (11) with needles (25) takes place before the injection of the plastic, in which the needles (25) are introduced through the fixed part (5) of the injection mold (1) by a suitable transport device (transport rollers 33).

A medical device is provided for irrigation of a patient wound site. The device contains a tube having a proximal portion adapted to receive an irrigation solution, a distal portion having a nozzle and an intermediate portion for transporting the solution. The tube has a barrel portion that may be manipulated by a user to position the device relative to the wound site. A distinctive nozzle has a body formed with a distally leading channel presenting a semispherical first spatial conformation and a proximally leading opening formed in the body presenting a second spatial conformation intersecting the semispherical terminus. This geometry, derived from principles of flow mechanics discussed herein, defines what will be described as an “effective diameter” of the nozzle. An assembly and system utilizing the device am also disclosed. The invention utilizes a fluid-isolating durable peristaltic pump for a continuous flow of irrigation solution, along with a single use tube set that embodies the device.

Provided is a method of manufacturing a microneedle array in which an active ingredient is concentrated at a tip while an active ingredient content is guaranteed. In order to achieve the object, a method of manufacturing a microneedle array in which needle-like recessed portions of a mold are filled with a liquid to form one dose of a patch includes determining a filling amount of the liquid from a difference in mass of the mold before and after filling of the liquid, determining a filling state of the liquid in the mold filled with the liquid, sucking the mold in which the filling amount and the filling state of the liquid are determined to be normal from a rear face, and evaporating and drying a solvent of the liquid of the sucked mold.

A tracheostoma device holder for holding a tracheostoma device superimposed of a tracheostoma of a person is provided. The tracheostoma device holder includes a flexible skirt for attachment over a tracheostoma via a skin adhesive proximal side thereof, and the skirt is provided with a through hole. A tubular tracheostoma device fitting is arranged circumferentially of the through hole, and the tubular tracheostoma device fitting extends distally from the distal side of the skirt. The skirt has at least two sheets, in form of a distal end sheet comprising a skin adhesive hydrogel or hydrocolloid, and a support sheet proximally of the distal end sheet. The support sheet includes polyurethane.