An apparatus is provided for producing and/or disengaging a fluid flow-capable medical threaded connection. The connection can be a Luer lock connection. The apparatus includes a first receiving device for receiving a first connecting element, and a second receiving device for receiving a second connecting element. The first receiving device and the second receiving device are rotatable relative to each other about a common screwing axis, and displaceable relative to each other along the screwing axis. The apparatus is designed to relatively move the first receiving device and the second receiving device toward and away from each other such that the first connecting element and the second connecting element can be screwed together or disengaged. An associated connecting element can be introduced into the first receiving device and/or into the second receiving device, in a radial direction relative to the screwing axis. A method is also provided.

A vented protective cap for a liquid dispenser, and a venting insert, in particular for such a protective cap. The protective cap has a cap wall which surrounds a cap interior. The cap wall has a venting aperture which is spanned by a flexible sheet-like structure. A boundary region of the sheet-like structure is fixed in an encircling manner to a boundary of the venting aperture. The sheet-like structure consists of at least two layers which bear directly against one another but, at least in a central region of the sheet-like structure, are not connected fixedly to one another.

A syringe, having a front portion carrying a hollow, axially extending needle, a container, running from said front portion and forming a container rear end portion, a plunger, extending and being movable axially in the container, the needle rear end being in fluid connection with the container and the plunger being arranged to suck liquid, e.g. a liquid comprising insulin, through the needle when drawn away from the needle and to discharge liquid through the needle when pushed towards the needle, the plunger having a piston portion, turned to the needle rear end, and a coupling portion arranged to co-act with the piston portion for moving the piston portion in the container.

A percutaneous circulatory support device includes a housing, a cannula coupled to the housing, the cannula having a first portion and a second portion, and wherein the cannula includes at least one slot disposed along at least the first portion of the cannula, the at least one slot configured such that the first portion of the cannula is defined by a first stiffness and a second portion of the cannula is defined by a second stiffness, the first stiffness being different than the second stiffness.

A tracheostomy tube has a machine end coupling (2) of a relatively hard plastics and formed with a retaining ring structure formation (23) at its patient end. This is joined with a tubular shaft (1) of a softer plastics, such as silicone, to form a subassembly (7) y a moulded interconnection of the machine end of the shaft about the retaining formation (23). An enlarged boss (12) at the rear end of the shaft (1) forms a forwardly facing wall (15). The tube also includes a moulded neck flange (5) of a relatively soft plastics with a central collar (50) having an internal, rearwardly facing wall (59). The boss (12) on the subassembly (7) is bonded into the collar (5) with the wall (15) on the boss abutting the wall (59) on the flange (5).

A medical syringe barrel and a manufacturing method for producing the same can be completed as a molded article by injection molding of a synthetic resin material without requiring post processing like polishing and can fill and administer a predetermined amount of the internal-use solution accurately. A medical syringe barrel includes a tubular barrel section for accommodating an internal-use solution in the interior thereof, an injection nozzle section formed at one end of the barrel section, and a flange section formed at an opening section on the other end of the barrel section to project radially outward. A surface of the flange section has a recess portion, and a weld line which is potentially formed by injection molding is not formed in the internal-use solution filled section.

A medicated thread manufacturing system and associated method includes first and second slideways, a thread clamping apparatus and a medicine spraying apparatus slidably arranged on the first slideway, and a thread winding apparatus slidably arranged on the second slideway. The clamping apparatus clamps two ends of a to-be-processed medicated thread, straightens the thread and twists the thread in the straightened state into a single-strand rope state. The spraying apparatus sprays a medicine towards a surface layer of the thread in the straightened state. The winding apparatus abuts a center position of the thread in the single-strand rope state, pulls and folds the thread, and rotates the thread such that the thread winds and extends from middle to two ends to be twisted in a double-strand rope state. A control apparatus is in signal connection and/or electrical connection to the clamping apparatus, the spraying apparatus and the winding apparatus.

A patient interface including a seal-forming structure with a textile membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patients nares and/or an entrance to the patients mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patients respiratory cycle, in use. The textile membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The taut state of the second portion is configured to allow the seal-forming structure to include a three-dimensional shape that has multiple curvatures.

Provided is a device for transdermal delivery of drugs. The device includes a separable substrate and is loaded with dual drugs based on an interpenetrating polymer network hydrogel. Also provided are methods of making and using the transdermal delivery device.

A tracheostomy tube (1) has a shaft (10, 10) including a helical reinforcing wire (30) overmoulded by a plastics material, such as of silicone. The wire has an indented path (31) traversing its turns in which is received a small-bore tube (32) so that this does not project above the surface of the shaft, or only forms a small projection. The small-bore tube (32) acts as an inflation line and opens at its patient end (33) within a sealing cuff (13). The machine end of the tube (32) is terminated by a combined inflation indicator and connector (36).