A method for accurately, rapidly and consistently cutting an opening in drape material for negative pressure wound therapy (NPWT) uses a cutting device that includes a plurality of cutting members that can extend from a bottom surface of the cutting device. A cover may fit over the bottom to protect the cutting members. The cutting members may be positioned to define a cut-out shape having dimensions designed for use with a NPWT system. An adhesive material may be formed on the bottom surface of the cutting device, inside of the cut-out shape defined by the cutting members. In use, the user presses the cutting tool onto the drape to cause the cutting members to cut into the drape and the adhesive to stick to the drape. When the user lifts the device, the drape, cut to the correct size and shape, is removed from the foam dressing covering the wound.

Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

The present invention discloses a sterile PRP separation kit that has compartmentalized container having a cover that allows for a stage-specific exposure of sterile components of the sterile PRP separation kit housed within stage-specific compartments to a non-sterile environment commensurate with a specific stage of operation of a separation process of PRP. The sterile PRP separation kit includes a PRP tube with segregated portals for injection of blood into the PRP tube, aspiration of PRP from the PRP tube, and for maintaining an interior pressure of the PRP tube at equilibrium with ambient pressure during both injection and aspiration.

An apparatus for vaccine generation includes a syringe with a cavity that includes a solution with photosensitizers. Microbial particles are added to the solution. A light source is capable of emitting one or more wavebands of light that are effectively absorbed by the one photosensitizers to generate singlet oxygen in the solution and other radical species that rapidly react with and damage lipids, proteins, DNA, and RNA of the microbial particles. This damage produces immunogens that can be applied as a vaccine to viruses and other infectious microbial particles. A plunger that fits within a proximal opening in the syringe is used for forcing the solution including the immunogens through the filter and out of the syringe while the photosensitizers, debris and unwanted microbial particles are trapped within the filter.

A supplemental device for attachment to an injection device, the supplemental device comprising: a housing; an electromechanical switch arrangement having an open state and a closed state, the electromechanical switch arrangement comprising a protrusion configured to contact a surface of the injection device while the supplemental device is attached to the injection device; a dose dialled detector operable to detect a dose of medicament dialled into the attached injection device; and a processor arrangement configured to: monitor the detected dose of medicament dialled into the attached injection device; detect a change in the state of the electromechanical switch arrangement; and change a display output of the supplemental device when a change in the state of the electromechanical switch arrangement is detected while a zero dose is dialled into the attached injection device.

The present disclosure provides a method of removing a cover from a bodily surface of a subject. The method may comprise applying a cover removal device to a portion of the cover that is disposed on the bodily surface of the subject, thereby generating a connection between the cover removal device and the portion of the cover. The method may comprise moving the cover removal device across the bodily surface of the subject in order to selectively remove the cover from the bodily surface and capture the cover onto the cover removal device, without the cover removal device substantially affecting or interfering with the bodily surface of the subject.

Devices and methods for trimming a stent to a desired length with an outer tube and an inner tube having a distal end and a diameter configured to receive a portion of the stent in excess of the desired length. The inner tube may move within the outer tube and the distal end may include an end effector configured to trim the portion from the stent while the device and stent are within a patient.

An apparatus comprises a first ring and a second ring. The second ring may be a clamp. The first ring may have a diameter and a cutout portion. The clamp may have a plurality of movable jaws and a plurality of teeth. The apparatus may further comprise a first sensor and a second sensor, each of which may include an alarm. A tubular connector may couple the ring, the clamp, and the sensor. The sensors may include a wireless transmitter that transmits to a portable or nonportable electronic device.

The invention provides an adaptor for a medicament delivery device is configured to enable a set dosage of a medicament to be drawn into and/or expelled from the device, the adaptor including: a body configured to be coupled to the device; an attachment portion movable with respect to the body and configured for attachment with a first part of the device; an engaging portion movable with the attachment portion; and a receiver configured to receive a movement constraint guide (MCG) and facilitate engagement between the engaging portion and the MCG; wherein the MCG includes one or more physical features defining at least an aspect of the set dosage; and wherein activation of said first part of the device to draw and/or expel the medicament is stopped when the set dosage is reached by engagement between the engaging portion and at least one of the one or more physical features of the MCG. The invention thus allows ready control of one or more aspects of dosage administration, which can be the amount of a dose and/or or the repeats of a dose.