Use of ultrasound beams to unlock the perception of mid-air tactile stimuli on hairy skin by using acoustic streaming is described. Such acoustic streaming is directional, more focused than fan and air-puff devices, doesn't require the use of cumbersome attachments, fast since it can be generated at a distance with the speed of sound, and can be used in a complementary fashion with vibrotactile mid-air stimulation deriving from the same hardware. Further proposed is a way to modulate the thermal perception of the mid-air tactile stimuli without the need for a thermal source or wearables. The effect of acoustic streaming and its thermal modulation may be combined for the accurate elicitation of affective touch sensations.

A system and method for dermal spraying includes a portable, hand-held dermal application device with one or more disposable cartridges that spray a dermal formulation onto the skin, the disposable cartridge having a nozzle that can be activated by placing the cartridge into the spray device.

A system and method for dermal spraying includes a portable, hand-held dermal application device with one or more disposable cartridges that spray a dermal formulation onto the skin, the disposable cartridge having a nozzle that can be activated by placing the cartridge into the spray device.

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

A rehabilitation assistant system for patients with cognitive impairments, including an audio stimulation unit, an acupoint stimulation unit, a phototherapeutic unit, an electronic stimulation unit, a display and optical frequency-flashed stimulation unit and a control unit. The audio stimulation unit broadcast a binaural beats with frequency following response, and the acupoint stimulation unit includes several acupoint agents to output physical stimulation to a user. The phototherapeutic unit includes two near-infrared light groups, and the electronic stimulation unit includes two electrical stimulation agents to output physical stimulation to the user. The display and optical frequency-flashed stimulation unit is switchable between a display mode and an optical frequency-flashed stimulation mode, and the control unit simultaneously controls the audio stimulation unit to broadcast the binaural beats with frequency following response so as to improve the rehabilitation efficiency in patients with cognitive impairment.

A skin treatment device and a method to cleanse and balance pH value of skin. The skin treatment device includes a nozzle to be directed into contact with the skin of a subject. A vacuum pump may be operably coupled to the nozzle for generating a suction force of the nozzle to evacuate impurities from the skin. A liquid replenishing assembly may be operably coupled to the nozzle for atomizing liquid at a pre-defined pH value. The liquid from the liquid replenishing assembly may pass into the nozzle based on the pre-defined pH value. The first control valve may be connected to an outlet of the vacuum pump and an outlet of the liquid replenishing assembly for communication with the nozzle.

A syringe for dermal regeneration comprises a body comprising inner and outer tubes, a cylinder filled with a first fluid being inserted into the inner tube from behind, and the outer tube being spaced apart from the inner tube and shaped to surround the inner tube such that a fillable space is formed between the inner tube and the outer tube and is filled with a second fluid; an injector coupled to the front portion of the body, the injector comprising a first part, a second part, and a third part; a through-hole formed through one side of the second part of the injector so as to communicate with the fillable space; and a check valve provided in the through-hole so as to block a flow of fluid from the injector to the fillable space and to allow a flow of fluid from the fillable space to the injector.

The subject matter described herein provides systems and techniques for enhancing a user’s performance. In particular, the physiological characteristics of the user can be altered toward target characteristics to bring about a particular physiological state in the user. Multiple physiological signals of the user may be sensed. Physiological characteristics indicative of a physiological state of the user may be determined. A differential between the physiological characteristics and selected target physiological characteristics may be determined. A selected energy signal associated with a correction action may be communicated to nerves associated with the user’s skin by outputting, using an energy generator, the energy signal toward the skin with one or more different energy types based on the differential. This may allow a particular targeted physiological state to be more rapidly brought about in the user.

A wearable apparatus capable of altering a physiological parameter such as the heart rate of a user to provide a relaxing or stimulating effect on the user is provided. The apparatus comprises a device capable of engaging the patient's skin to provide a rhythmic tactile stimulus to the user that can alter the user's heart rate and an arrangement for securing the device to the user such that the device can apply the stimulus to the user. The apparatus may be part of a system enabling the device to be controlled remotely. The apparatus may also be configured to provide additional tactile stimuli.

Disclosed herein are devices (e.g., needles (e.g., hollow needles), hollow staples, articles, apparatuses, and systems), kits, and methods for treating skin and skin conditions, for example, by promoting skin tightening, such as by reducing skin laxity and reducing tissue area or volume.