Disclosed is a localized method for treatment of cancer including the steps of providing a drug delivery catheter; navigating the catheter to the bile duct; and delivering a therapeutic agent into the bile duct. According to one aspect of the method, the drug delivery catheter is a multi-occlusion balloon catheter. The multi-occlusion balloon catheter may include at least two balloons. The multi-occlusion balloon catheter may optionally include a pressure transducer between the balloons to optimize delivery technique.

A tubing assembly for use with an electronic catheter guidance systems is provided and includes a catheter and a stimulation electrode assembly, and an electrical connection for delivering a stimulation waveform to the stimulation electrode assembly. The catheter extends in a longitudinal direction and has a proximal end and a distal end that define a lumen therebetween. Further, the catheter is configured for placement within a patient's digestive tract. The stimulation electrode assembly is configured to deliver an electrical stimulation to tissue. A catheter guidance system and method for accurately placing a catheter in the digestive tract are also provided.

A system for managing mechanical ventilation provided to a patient by a ventilator. The system includes a plurality of electrodes for being adhered to the patient's chest and a controller in communication with the plurality of electrodes, the controller being programmed to determine from signals received from the electrodes metrics of the patient including: a measure of breathing effort of the patient, and one or both of a heart rate of the patient and/or a respiration rate of the patient. The system further includes a user interface in communication with the controller. The controller is adapted to communicate the metrics to the user interface which is adapted to receive and concurrently display a representation of the measure of breathing effort of the patient on the display; and/or control operation of the ventilator and utilize the measure of breathing effort of the patient in a control algorithm governing such operation.

The invention pertains to a wearable pressure-applying device designed for user comfort and convenience. The device features multiple securing mechanisms for attachment to the user, including adaptable closures such as zippers. A manual or mechanical engagement system allows the user to adjust the constriction of the device, applying pressure as desired. Notably, the closure mechanisms do not extend across the entire vertical length of the wearable device, enhancing flexibility and comfort. The constriction mechanism employs either threaded or stringed lacing methods, with separable connections for user attachment and removal. An ergonomically contoured handle, easily attachable and detachable via a coupler, enhances usability. Additionally, a cord lock mechanism ensures precise pressure control, with a quick-release feature for instant pressure relief. Modular attachment options for both mechanical and cord-lock mechanisms offer versatility. Furthermore, advanced versions of the device may incorporate battery-powered or sensor-driven pressure application capabilities, with potential for wireless control.

Aspects discussed herein relate to remixing devices that can be used to modify a gas mix being inhaled by a user. The device can accurately adjust inspired CO2 and/or 02 levels independently to a desired level. Aspects described herein generally improve the quality, efficiency, and speed of devices to provide breathing gas mixes. Medical conditions can be diagnosed and a therapeutically effective gas mix can be provided as treatment for diagnosed medical conditions.

A hose retaining device is disclosed herein. The hose retaining device includes a strap assembly coupled to a padding portion having a top surface, a protruding member, and a retaining loop. The strap assembly further includes hook portion, a loop portion, and a fastening slot for turning the strap assembly back upon itself to couple the hook portion to the loop portion. The retaining loop includes an underside configured to receive and retain a corrugated tubing having a plurality of sunken portions and a plurality of protruding portions. The hose retaining device is useful for keeping a corrugated tubing item, commonly used in conjunction with a breathing assistance device, out of the way of the user to increase comfort and stability.

Systems and methods for reducing vibrations perceived by a human due to an artificial heart valve include a vest that is wearable around a torso of the human, a plurality of sensors mounted to the vest, a plurality of vibration-generating actuators mounted to the vest, and a controller. The plurality of sensors detects vibrations in the human generated by the artificial heart valve. The controller is operable to receive signals representing the detected vibrations from the plurality of sensors, and is operable to produce anti-vibration signals that substantially attenuate the detected vibrations. A first sensor of the plurality of sensors is located near a first vibration-generating actuator of the plurality of vibration-generating actuators to form a sensor/actuator set. In the sensor/actuator set, the anti-vibration signals generated by the controller for the first vibration-generating actuator correspond to the vibrations detected by the first sensor.

One aspect described herein is a data communication apparatus. The apparatus may comprise: electronic components operable to gather and output different types of physiological measurements associated with a user's chest, the electronic components comprising a multimodal sensor array, a transceiver, and a power source; and a housing that contains the electronic components and comprises an attachment element operable to maintain an alignment of the multimodal sensor array over the user's chest, wherein, when the housing is maintained over the user's chest, the multimodal sensor array is operable with the power source to measure the different types of physiological measurements, and the transceiver is operable with the power source and the sensor array to output the different types of physiological measurements to an external device. Related apparatus, devices, methods, and systems also are described.

A relaxation device includes an enclosure, a vibrator, a scent release mechanism, at least one processing device, and a power source. The vibrator is provided in the enclosure and is configured to induce vibrations of at least a portion of the enclosure. The scent release mechanism is at least partially mounted within the enclosure. The processing device is in electrical communication with the vibrator and the scent release mechanism and is configured to control operation of the vibrator and the scent release mechanism. The power source is in the enclosure and electrically connected with the processing device, the vibrator and the scent release mechanism.

A postoperative chest drainage device for draining fluids that originate from the chest of a patient and which has liquids and/or gases, the device includes: a bag for collecting the liquids and an input connector adapted to be connected to a drainage duct for the passage of the fluids that originate from the chest toward the bag, and an air-liquid separation device which is arranged outside of the bag, between the input connector and the bag, and is configured to allow the passage of the gases, when they are present in such fluids, toward the environment outside the bag and to direct the liquids, when present in the fluids, toward the bag