A system and method for improving limb function through the use of percutaneous mechanical and neural interfaces. The system generally uses a hollow long bone axial rod that is inserted into the long bone medullary cavity. A transfer rod with a central channel is mounted to the long bone axial rod. An exterior body attachment is connected to the transfer rod and attachment rings attach muscle groups, fascia layers and dermal layers to the transfer rod. Additionally, the system is configured to collect and transmit nerve signaling data to an external processor and additionally configured to transmit data from the external processor to the plurality of nerves.

A system for attachment of a device to a bone is provided. The system includes an internal axial rod with a proximal and distal end that is configured to be inserted and secured into a bone cavity's distal end. The system can also include an internal-external transfer rod with a proximal and distal end mounted into the distal end of the axial rod and a central channel extending through the transfer rod from the proximal end to the distal end and a plurality of attachment rings for attaching at least one tissue or muscle group to the transfer rod. The system also includes a bio-compatible and bio-occlusive artificial membranes (BIOCAMS) lamina, wherein the lamina includes either a polyetheretherketone (PEEK) mesh, a biocompatible polymer, a carbon fiber polymer, an artificial tissue polymer, molded donor tissue, allogenic tissue, a collagen/hyaluronic acid-based tissue, or connective tissue biosynthetic substrate material suitable as webbing.

Disclosed is a wearable device for being worn on the torso of a user, at least one of limbs of the user or a combination thereof. The wearable device comprises a wearable body and at least one positioning unit , wherein the wearable body has at least two fixing parts respectively fixed on at least two adjacent movable joints of the user, so that the wearable body is fitted to the torso, the at least one of the limbs or the combination thereof; the wearable body forms a positioning region between the fixing parts ; a portion, between the two adjacent movable joints, of the torso, the at least one of the limbs or the combination thereof located is located in the positioning region; and the positioning unit is configured in the positioning region to correspond to a specific position of the user.

The present invention provides a wearable device, a system for manufacturing a wearable device and a method of neural activity control. The device for temporal interference simulation includes a pair of electrodes at penalizable location. The electrodes each send out a high frequency electromagnetic fields with a very slight difference in the two frequencies. The fields superimpose at a specified region of the brain, which is customized depending on the location of neural activity control, to create a low frequency refractory wave envelope. The low frequency wave inhibits or stimulates local neurons to control electrical activity within that region.

This invention controls stimulation levels and cycling cadence on an FES ergometer to minimize or prevent the occurrence of spasm in spinal cord injured or other neurologically impaired patients.

A vaginal device is described. A conformable vaginal insert is shaped for insertion into a vaginal cavity of a female human. A contact point is configured to change a shape of the insert. A sensor is configured to measure and to relay characteristics of the vaginal cavity and the surrounding and supportive structures of the vaginal cavity. A processor is configured to control the contact point to adjust the shape of the insert, generate a treatment for the vaginal cavity and the surrounding structures of the vaginal cavity and the supportive structures of the vaginal cavity comprising a vaginal cavity profile generated from the measured characteristics, store the measured characteristics and the vaginal cavity profile, and based on the stored measured characteristics and the stored vaginal cavity profile, automatically modify the shape of the insert by control of the contact point to provide the treatment to the vaginal cavity.

Apparatuses and methods for treating a heart failure patient by ablating a nerve of the thoracic splanchnic sympathetic nervous system to increase venous capacitance and reduce pulmonary blood pressure. A method comprising: inserting a catheter into a vein adjacent the nerve, applying stimulation energy and observing hemodynamic effects, applying ablation energy and observing hemodynamic effects, applying stimulation energy after the ablation and observing hemodynamic effects and monitoring for presence of the lung in the ablation zone. An alternative method comprising: inserting a catheter into a vein adjacent the nerve, detecting that lung tissue is a safe distance from an ablation zone, and delivering ablation energy to the target nerve when lung tissue is a safe distance from the ablation zone.

Disclosed is a method and device for inactivating or killing airborne bacteria, fungi, molds and viruses by passing the air through a filter material formed of a fabric having particles of zinc disposed in discrete physically isolated locations, wherein the particles of zinc and oxygen from the air form half cells of a battery whereby to create an electrical field that inactivates or kills airborne bacteria, fungi, molds and viruses passing through the filter material.

A cartridge for applying an electromagnetic field (EMF) to at least one toxin in a wound in the skin of a person or animal is provided. The cartridge includes a power supply, a controller coupled to the power supply and providing a voltage between about 0.2V and 3V to an array of electrodes configured to transmit the EMF to the skin about the wound site. A cartridge for applying an ultrasonic field to at least one toxin in a wound in the skin of a person or animal is also provided. The ultrasonic cartridge may include a power supply, a controller coupled to the power supply and providing a voltage to at least one sonotrodes configured to transmit the ultrasonic field to the skin about the wound. The cartridge may also include a sensor for measuring the resistance or impedance in the tissue to be treated and the controller can adjust the ultrasonic field based on the impedance or resistance.

A cartridge for applying an electromagnetic field (EMF) to at least one toxin in a wound in the skin of a person or animal is provided. The cartridge includes a power supply, a controller coupled to the power supply and providing a voltage between about 0.2V and 3V to an array of electrodes configured to transmit the EMF to the skin about the wound site. A cartridge for applying an ultrasonic field to at least one toxin in a wound in the skin of a person or animal is also provided. The ultrasonic cartridge may include a power supply, a controller coupled to the power supply and providing a voltage to at least one sonotrodes configured to transmit the ultrasonic field to the skin about the wound. The cartridge may also include a sensor for measuring the resistance or impedance in the tissue to be treated and the controller can adjust the ultrasonic field based on the impedance or resistance.