Various embodiments of a system and method for the treatment of brain cancer using a subdurally-implanted alternating electric field generation apparatus are disclosed herein.

A bone growth stimulator includes an antenna configured to receive electromagnetic signals in a radio frequency band, and a controller having a power source including a supercapacitor electrically connected to the antenna. The supercapacitor stores a charge in accordance with the electromagnetic signals received by the antenna. The bone growth stimulator further includes a cathode extending from the controller to a desired location of bone growth and an anode electrically connected to the power source and extending from the controller. Electrical energy travelling from the anode to the cathode stimulates bone growth in a patient.

A bone growth stimulator includes an antenna configured to receive electromagnetic signals in a radio frequency band, and a controller having a power source including a supercapacitor electrically connected to the antenna. The supercapacitor stores a charge in accordance with the electromagnetic signals received by the antenna. The bone growth stimulator further includes a cathode extending from the controller to a desired location of bone growth and an anode electrically connected to the power source and extending from the controller. Electrical energy travelling from the anode to the cathode stimulates bone growth in a patient.

A cosmetic method for treating a skin of a person is presented, the method comprises inserting one or more needles to one or more depths into the skin of the person such that at least a tip of at least one needle of the one or more needles is deployed within a muscle layer of the person's skin; applying a negative DC voltage to the one or more needles, while a skin of the person is in contact with a positive electrode to form one or more closed circuits of DC current through the person's body; and providing the DC current for a pre-selected amount of time to damage and/or ablate muscles and/or muscle nerve cells in the muscle layer; thereby providing a skin treatment comprising reducing and/or smoothing wrinkles from the person's skin.

A system for detecting presence of coronavirus in a subject, the system including a first pad for placing a first hand, the pad including a contact to measure conductance of the subject's body, a conductance meter connected to the contact, a second pad for placing a second hand, a source of electromagnetic radiation for irradiating the second pad. A system for detecting presence of coronavirus in a subject, the system including a chip with a plurality of wires disposed on or in the chip, a conductance meter arranged to measure conductance between the wires, and biological material associated with the coronavirus disposed on or in the chip. Related apparatus and methods are also described.

A method and system capable of applying microwave therapy guided by thermoacoustic imaging and/or thermoacoustic thermometry is disclosed. The system includes a thermoacoustic imaging system and/or a thermoacoustic thermometry system that generate(s) a map of a region of interest; and a microwave therapy system that targets the region of interest using the map, and that applies the microwave therapy to the targeted region of interest. Treatment of the targeted region of interest may be employed by the microwave therapy system using real-time feedback from the thermoacoustic imaging system and/or the thermoacoustic thermometry system. Imaging and therapy may be automatically co-registered.

Disclosed are apparatus, compositions, and methods for promoting regeneration of tissue on a subject such as a wounded, damaged, or injured appendage, or within a subject such as a wounded, damaged, or injured organ. The disclosed apparatus, composition, and methods include or utilize wearable sleeves and regenerative compositions.

A system and method for delivering TTFields are herein described. The system comprises an electric field generator generating a signal having a frequency from 50 kHz to 500 kHz and coupled to a first lead and a second lead. A first pad is coupled to the first lead and includes a conductive foam and a first conductive gel. The conductive foam receives the signal from the first conductive lead and comprises a solid continuous phase material comprising at least a conductive material. A plurality of pockets is interspersed throughout the conductive foam. The first conductive gel is attached, absorbed, or adsorbed to the conductive foam. The second lead is coupled to the electric field generator and a second pad is coupled to the second lead. The second pad has a second electrode element connected to a second conductive gel element and receives the signal from the second conductive lead.

A system and method for delivering TTFields are herein described. The system comprises an electric field generator generating a signal having a frequency from 50 kHz to 500 kHz and coupled to a first lead and a second lead. A first pad is coupled to the first lead and includes a conductive foam and a first conductive gel. The conductive foam receives the signal from the first conductive lead and comprises a solid continuous phase material comprising at least a conductive material. A plurality of pockets is interspersed throughout the conductive foam. The first conductive gel is attached, absorbed, or adsorbed to the conductive foam. The second lead is coupled to the electric field generator and a second pad is coupled to the second lead. The second pad has a second electrode element connected to a second conductive gel element and receives the signal from the second conductive lead.

A system for therapeutic treatments with electromagnetic waves is described. The system comprises an antenna and an apparatus configured to generate a supply current for the antenna in order to generate the electromagnetic waves. The apparatus comprises a digital processing circuit configured to generate a first PWM signal, a switching stage configured to generate an amplified PWM signal, an analog low-pass or band-pass filter configured to generate the supply current by filtering the amplified PWM signal, and a current sensor configured to provide a digital sample indicative of the amplitude of the supply current.

Specifically, the digital processing circuit generates a sequence of first digital values of a periodic base pulse. Moreover, the digital processing circuit generates a second PWM signal having a packet switch-on period and a packet switch-off period, generates a third PWM signal having a train switch-on period and a train switch-off period, and generates an enable signal as a function of the second PWM signal and the third PWM signal. The digital processing circuit generates then a second digital value, wherein the second digital value is set to the first digital value when the enable signal has a first logic level and to zero when the enable signal has a second logic level.

In particular, the digital processing circuit generates the first PWM signal as a function of a third digital value indicative of the duty cycle of the first PWM signal, and varies the third digital value via a discrete proportional-integral regulation configured to regulate the difference between the second digital value and the digital sample to zero.