A light therapy device used for a negative-pressure cup is provided. The light therapy device includes a carrier, a light therapy assembly, a negative ion assembly and a needle protection cap. The carrier is disposed in the negative-pressure cup and includes a panel. The light therapy assembly and the negative ion assembly are disposed in the carrier. The negative ion assembly includes a releasing needle. The releasing needle projects out from the panel to release negative ions. The needle protection cap covers the panel corresponding to the releasing needle to shield the releasing needle. Therefore, the light therapy assembly and the negative ion assembly may be associated with the negative-pressure cup for usage, and the needle protection cap may prevent the user from being stabbed.

Provided are a device whereby, during process of a process target such as a cell or the like, localized process of a process part is possible without inflicting damage due to heat, and rejoining and regeneration may proceed readily subsequent to process, and whereby an injection substance may be introduced efficiently; and a device for generating bubbles containing a plasma. Through the use of a localized ablation device employing a bubble jetting member having a core formed from a conductive material, a shell part formed from an insulating material, covering the core and including a section extending from the tip of the core, and a space formed between the extended section of the shell part and the tip of the core, a process target can be treated in localized fashion and without inflicting damage. By further providing an outside shell part at the outer periphery of the shell part, bubbles onto which a solution containing an injection substance has been adsorbed can be ejected, and the injection substance can be introduced during localized ablation of the process target. Additionally, by including a pair of electrodes formed from a conducting material, for generating a plasma in an inert gas, a liquid flow passage through which a liquid flows, and a microscopic flow passage for flow of an inert gas, an inert gas containing a plasma, and bubbles of inert gas containing a plasma, the liquid flow passage and the microscopic flow passage connecting at the downstream side from a section in which plasma is generated in the microscopic flow passage, bubbles containing a plasma can be generated, and can maintain a plasma state even in liquid, whereby therapy of biological tissue can be effected with the plasma.

Provided are a device whereby, during process of a process target such as a cell or the like, localized process of a process part is possible without inflicting damage due to heat, and rejoining and regeneration may proceed readily subsequent to process, and whereby an injection substance may be introduced efficiently; and a device for generating bubbles containing a plasma. Through the use of a localized ablation device employing a bubble jetting member having a core formed from a conductive material, a shell part formed from an insulating material, covering the core and including a section extending from the tip of the core, and a space formed between the extended section of the shell part and the tip of the core, a process target can be treated in localized fashion and without inflicting damage. By further providing an outside shell part at the outer periphery of the shell part, bubbles onto which a solution containing an injection substance has been adsorbed can be ejected, and the injection substance can be introduced during localized ablation of the process target. Additionally, by including a pair of electrodes formed from a conducting material, for generating a plasma in an inert gas, a liquid flow passage through which a liquid flows, and a microscopic flow passage for flow of an inert gas, an inert gas containing a plasma, and bubbles of inert gas containing a plasma, the liquid flow passage and the microscopic flow passage connecting at the downstream side from a section in which plasma is generated in the microscopic flow passage, bubbles containing a plasma can be generated, and can maintain a plasma state even in liquid, whereby therapy of biological tissue can be effected with the plasma.

An oral care process which includes initiating a first operational sequence which includes generating an electric potential between a first sacrificial electrode and a second sacrificial electrode, the electric potential in the first operational sequence beginning with one of a first polarity and a second polarity, stopping the first operational sequence, and commencing a second operational sequence which includes generating the electric potential between the first sacrificial electrode and the second sacrificial electrode. The electric potential in the second operational sequence may begin with the other of the first polarity and the second polarity. The electric potential may be alternated between the first polarity and the second polarity at predetermined intervals during at least one of the first operational sequence and the second operational sequence.

Exemplary systems and methods associated with trans-tissue substance delivery using non-thermal plasma to porate skin or tissues using contoured dielectrics/electrodes and grounding techniques. In some embodiments, a substance delivery system may be incorporated into the plasma generating device for automatically controlled skin treatments. In other embodiments, a skin treatment patch may include the electrode and the treatment substance.

Exemplary systems and methods associated with trans-tissue substance delivery using non-thermal plasma to porate skin or tissues using contoured dielectrics/electrodes and grounding techniques. In some embodiments, a substance delivery system may be incorporated into the plasma generating device for automatically controlled skin treatments. In other embodiments, a skin treatment patch may include the electrode and the treatment substance.

Aspects described herein pertain to restoring damaged portions of tooth or bone using plasma mediated deposition. In an embodiment, a biocompatible carrier gas is ionized to form a biocompatible atmospheric plasma stream. Restoration material, such as nano-scale powdered hydroxyapatite, is introduced into the plasma stream, which is then applied to a damaged portion of a bone or tooth. The restoration material is deposited on the damaged portion of the bone or tooth, thus restoring a shape and mechanical integrity of the bone or tooth.

Aspects described herein pertain to restoring damaged portions of tooth or bone using plasma mediated deposition. In an embodiment, a biocompatible carrier gas is ionized to form a biocompatible atmospheric plasma stream. Restoration material, such as nano-scale powdered hydroxyapatite, is introduced into the plasma stream, which is then applied to a damaged portion of a bone or tooth. The restoration material is deposited on the damaged portion of the bone or tooth, thus restoring a shape and mechanical integrity of the bone or tooth.

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.