A focusing device for X-ray and Gamma-ray use in radiotherapy, the device comprising a radiopaque frustoconical shaped member having a first end and a second end, wherein the member comprises an array of radiolucent beam paths extending from the first end to the second end, wherein each of the beam paths has an entrance aperture at the first end, and an exit aperture at the second end; the entrance aperture through which source rays pass into the beam path, wherein the beam path emits a beam from the exit aperture when the source beams are in line with the longitudinal axis of the beam path or having a predetermined angle of deviation from the longitudinal axis of the beam paths; and wherein each of the longitudinal axis of the beam paths is angled relative to the longitudinal axis of the member for convergence towards a focal point or multiple points.

A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.

The present disclosure is directed to fatty-acid glycerol ester derivative compounds containing a targeting bisphosphonate group. The disclosure further include pharmaceutical or biomedical compositions comprising these compounds, and methods of using these compounds and compositions forming microbubbles. The microbubbles have affinity for metal-containing, especially calcium-containing, bodies and/or biological targets. In certain embodiments, these compositions are useful for providing targeted placement of microbubbles capable of cavitation on application of high frequency energy.

The present disclosure is directed to fatty-acid glycerol ester derivative compounds containing a targeting bisphosphonate group. The disclosure further include pharmaceutical or biomedical compositions comprising these compounds, and methods of using these compounds and compositions forming microbubbles. The microbubbles have affinity for metal-containing, especially calcium-containing, bodies and/or biological targets. In certain embodiments, these compositions are useful for providing targeted placement of microbubbles capable of cavitation on application of high frequency energy.

An apparatus and method for improving microcirculation by suppressing and cancelling the negative effects of electromagnetic radiation from cellular phones and computers connected to wireless networks on microcirculation. The apparatus generates frequencies that are synchronized and in opposed amplitudes to the detected electromagnetic radiation frequencies, thereby suppressing and cancelling the negative effects of the electromagnetic radiation frequencies on microcirculation.

An apparatus and method for improving microcirculation by suppressing and cancelling the negative effects of electromagnetic radiation from cellular phones and computers connected to wireless networks on microcirculation. The apparatus generates frequencies that are synchronized and in opposed amplitudes to the detected electromagnetic radiation frequencies, thereby suppressing and cancelling the negative effects of the electromagnetic radiation frequencies on microcirculation.

A process that provides protective therapy for biological tissues or fluids includes applying a pulsed energy source to a target tissue or a target fluid having a chronic progressive disease or a risk of having a chronic progressive disease to therapeutically or prophylactically treat the target tissue or target fluid. The pulsed energy source has energy parameters selected so as to raise the target tissue or bodily target fluid temperature up to a predetermined temperature for a short period of time to achieve a therapeutic or prophylactic effect, while the average temperature rise of the target tissue or target fluid over a longer period of time is maintained at or below a predetermined level so as not to permanently damage the target tissue or target fluid.

The present disclosure provides, inter alia, a system and methods for targeted hyperthermia effective to differentially heat target organs. In certain embodiments, the system and/or method utilizes one or more pairs of inductive applicators coupled to the one or more RF generators and configured to deposit radio frequency radiation on a region of interest based on a set of configurable parameters.

An oral hygiene device comprises a housing having an outside mouth portion and an inside mouth portion, at least one energy delivery element disposed in or on the inside mouth portion, configured to deliver energy to one or more teeth of a subject, a controller disposed in the outside mouth portion electrically connected to the at least one energy delivery element, an energy storage unit disposed in the outside mouth portion, and a sleeve removably connected to the inside mouth portion of the housing, the sleeve having upper and lower channels configured to accept the upper and lower teeth of the subject. A method of using an oral hygiene device and a method of administering an oral hygiene treatment are also described.

An improved positioning device (the DEVICE) comprises a new and unique concave angulated device for at least one of, but not limited to, stretching, supporting, bracing, rehabilitating, positioning, massaging, kneading, scratching, or exercising a body of a user. The DEVICE's new concave angulated and more user friendly surface addresses the need for a more anatomically responsive body positioning DEVICE for achieving improved results relative to, among other things, the above uses. This DEVICE includes multiple embodiments, which also may comprise various possible configurations, that enable the DEVICE to also function as a fulcrum or lever and/or be capable of uniquely dispersing a load during the interaction between the user and the DEVICE.