Ferritin or iron-based image enhancement agents identify target tissue for treatment or ablation and are heated by microwave absorption. Microwave heat substrates enhance microwave hyperthermal ablation treatment, and may be percutaneously delivered and imaged by x-ray CT during placement of the microwave treatment antenna, allowing more precise positioning and more complete ablation of a tumor site. One method of treating a target tissue uses image-guided delivery of a heat substrate with a reverse-phase change polymer, and may apply energy to fix a mass of the material in the tissue. The fixed polymer may increase hyperthermia, form a thermal boundary, or blockade a vessel or passage so as to reduce or prevent undesired conductive cooling by contiguous tissue, or may deliver a localized treatment drug at the site, upon heating or as it degrades over time.

Methods and apparatus for the treatment, management and/or control of pain, in particular pain associated with, or caused or contributed to by, certain dermatological conditions.

The unit for non-invasive stimulation of visual cortex cells in severe visual impairment comprises the image sensor (1) provided with the video chip (2) connected to the control processor (9) to convert the image signal to signals capable of stimulating the brain, to which the first transmitting sensor (3) for self-stimulation, the second transmitting sensor (4) of the position stabilisation and the receiving sensor (8) of the position stabilisation feedback are connected via the position stabilisation unit (6), wherein these sensors are connected to the carrier (16) of the active/passive sensors (7) via transmitting active/passive sensors (7) of the position stabilisation feedback. The communication module is connected to the control processor (9); this communication module may be interconnected to the mobile unit (15), and the individual elements may be placed within the supporting structure (5).

The unit for non-invasive stimulation of visual cortex cells in severe visual impairment comprises the image sensor (1) provided with the video chip (2) connected to the control processor (9) to convert the image signal to signals capable of stimulating the brain, to which the first transmitting sensor (3) for self-stimulation, the second transmitting sensor (4) of the position stabilisation and the receiving sensor (8) of the position stabilisation feedback are connected via the position stabilisation unit (6), wherein these sensors are connected to the carrier (16) of the active/passive sensors (7) via transmitting active/passive sensors (7) of the position stabilisation feedback. The communication module is connected to the control processor (9); this communication module may be interconnected to the mobile unit (15), and the individual elements may be placed within the supporting structure (5).

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.

A dual-mode microwave applicator for treating tissue comprises a control unit, a rod-shaped element, a coaxial line, and a metal sleeve. The control unit controls the applicator in an application mode and a sensing mode. In the application mode microwave radiation is applied and during the sensing mode tumorous tissue is detected. The rod-shaped element comprises a tip. The coaxial line is formed in the rod-shaped element to relay microwaves to the tip for treatment of the tissue. The coaxial line comprises an inner conductor and an outer conductor. The outer conductor includes a slot of a slot length formed at a slot distance from the tip. The metal sleeve at a sleeve distance from the slot. The sleeve distance is about 0.55 mm, the slot length is about 1.75 mm, and the slot distance is about 7.7 mm.

Provided herein are systems, devices and methods for the treatment of fungus. In particular, provided herein are systems, devices and methods employing energy to nail and tissue structures to treat fungal infection.

Ferritin or iron-based image enhancement agents identify target tissue for treatment or ablation and are heated by microwave absorption. Microwave heat substrates enhance microwave hyperthermal ablation treatment, and may be percutaneously delivered and imaged by x-ray CT during placement of the microwave treatment antenna, allowing more precise positioning and more complete ablation of a tumor site. One method of treating a target tissue uses image-guided delivery of a heat substrate with a reverse-phase change polymer, and may apply energy to fix a mass of the material in the tissue. The fixed polymer may increase hyperthermia, form a thermal boundary, or blockade a vessel or passage so as to reduce or prevent undesired conductive cooling by contiguous tissue, or may deliver a localized treatment drug at the site, upon heating or as it degrades over time.

A microwave heat spread apparatus and an operating method thereof are provided. The microwave heat spread apparatus includes: a plurality of antennas respectively disposed at a plurality of positions of the human body and radiating microwaves into the human body; a plurality of channel transceivers respectively connected to the plurality of antennas and configured to transmit and receive the microwaves through a corresponding antenna; a transmission signal distributor configured to distribute a signal to each of the plurality of channel transceivers; a controller configured to control transmission and reception of signals through the channel transceivers; and a detector configured to detect a difference between a signal received through a channel transceiver after passing through the human body and a signal before passing through the human body.