A cartridge for applying an electromagnetic field (EMF) to at least one toxin in a wound in the skin of a person or animal is provided. The cartridge includes a power supply, a controller coupled to the power supply and providing a voltage between about 0.2V and 3V to an array of electrodes configured to transmit the EMF to the skin about the wound site. A cartridge for applying an ultrasonic field to at least one toxin in a wound in the skin of a person or animal is also provided. The ultrasonic cartridge may include a power supply, a controller coupled to the power supply and providing a voltage to at least one sonotrodes configured to transmit the ultrasonic field to the skin about the wound. The cartridge may also include a sensor for measuring the resistance or impedance in the tissue to be treated and the controller can adjust the ultrasonic field based on the impedance or resistance.

Disclosed are a method of radiating wave energy available for unmanned automatic operation and apparatuses for performing the same. The method includes obtaining a dielectric characteristic of a object by performing a reconstruction calculation based on a scattered signal that is scattered from the object and pre-measured information on the object, determining a wave radiation parameter for adjusting energy of a wave to be radiated to a lesion of the object by performing a characteristic analysis operation based on the dielectric characteristic, and determining the energy of the wave to be high-power energy based on the wave radiation parameter.

Apparatus and methods for deactivating bronchial nerves extending along the secondary bronchial branches of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the secondary bronchial section to be treated. The ultrasonic transducer emits circumferential ultrasound so as to heat tissues throughout circular impact volume (13) as, for example, at least about 1 cm.sup.3 encompassing the bronchus to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual bronchial nerves.

The apparatus and methods utilized for lung tumor ablation.

An apparatus for patient-specific adjusting of ultrasound output pressure includes a controller (118) configured for adjusting, based on an estimate of thickness of a temporal bone (140) in a head of a medical treatment recipient, a pressure setting. It may also be based on treatment depth (134). Ultrasound at the adjusted pressure setting is applied. A user interface may be provided for user entry of the estimate, the user interface being further configured for user indication of the treatment depth. Both the entered estimate and the indicated treatment depth may be used in calculating ultrasound attenuation (148). The user indication can be interactive by virtue of designating, on a display, a location of a treatment target. The calculated attenuation may be a value, in decibels, that is in a range from 0.9×(2.70×0.1+16.60×T+0.87×(D−T−0.1)+3.02) to 1.1×(2.70×0.1+16.60×T+0.87×(D−T−0.1)+3.02), where T is the estimate in centimeters and D is the treatment depth in centimeters.

A therapy apparatus for treating tissue by the emission of focused ultrasound waves, including:

a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve (S1, S2, . . . ) with centres of curvature;

centres of curvature (c.sub.1, c.sub.2, . . . ) asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry (A1) or from the axis of symmetry (S) and/or at different depths taken according to the axis of symmetry;

the individual axes (a.sub.1, a.sub.2, . . . ) intersecting between the focal zones (Zc.sub.1, Zc.sub.2, . . . ) and the creation surface (8) or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone (Zr) which is off-axis relative to the plane of symmetry (A1) or to the axis of symmetry (S);

the sectors of this creation surface (8) creating energy deposit zones with profiles corresponding to the focal coverage zones (Zr).

Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.

An approach for enhancing radiation treatment of target tissue includes identifying a target volume of the target tissue; causing disruption of vascular tissue in a region confined to the target volume so as to define the target volume; based at least in part on the disruption of the vascular tissue, determining a radiation treatment plan having a reduced radiation dose for treating the target tissue; and exposing the target volume to the reduced radiation dose based on the radiation treatment plan.

Disclosed herein are compositions and methods for labeling cells using click chemistry reagents. The compositions and methods disclosed herein provide a specific and efficient means of localizing desired agents to a variety of cell types in vivo and in vitro.

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

A probe (10) transmits and receives diagnostic ultrasound and therapeutic ultrasound. A transmission unit (12) forms a transmission beam of the therapeutic ultrasound having a higher wave number than the diagnostic ultrasound and scans the transmission beam of the therapeutic ultrasound in a therapeutic region set inside a diagnostic region by controlling the probe (10). Since the therapeutic ultrasound having a higher wave number than the diagnostic ultrasound is used, the therapeutic effect is higher than when using a therapeutic ultrasound having a similar wave number to the diagnostic ultrasound, and since the transmission beam of the therapeutic ultrasound is scanned in the therapeutic region, the therapeutic effect is higher than when the transmission beam of the therapeutic ultrasound is not scanned.