Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.

In one example in accordance with the present disclosure, an imaging device is described. The imaging device includes an array of transducers. Each transducer includes an array of piezoelectric elements. Each piezoelectric element transmits pressure waves towards an object to be imaged and receives reflections of the pressure waves off the object to be imaged. The imaging device also includes a transmit channel per one or more piezoelectric elements to generate the pressure waves and a receive channel per one or more piezoelectric elements to process the reflections of the pressure waves. The number of channels are selectively altered to control parameters such as power consumption and temperature.

The disclosure provides systems for ultrasound-induced thrombolysis with magnetic microbubbles under a rotational/alternating magnetic field, sonothrombolysis systems with magnetic microbubbles and optional nanodroplets for inducing thrombolysis under an acoustic field, and a rotational/alternating magnetic field, and methods of treating patients with blood clots using the sonothrombolysis systems of the present disclosure.

A flexible guidewire assembly has an energy-emitting device configured to be selectively activated in response to receiving a first activation signal transmittable from a control assembly. This is done in such a way that the energy-emitting device, once activated, emits a first amount of electro-magnetic energy. The first amount of electro-magnetic energy has a first strength that is (A) sufficient for detection by a medical-imaging sensor positioned in the confined space defined by the living body, and (B) insufficient for vaporization of any tissue of the living body.

A catheter system for ablation of tissue around a blood vessel, e.g., the pulmonary artery, to reduce neural activity of nerves surrounding the blood vessel. The catheter system includes an elongate shaft having a proximal portion coupled to a handle, and a distal portion. The distal portion includes a transducer and an expandable anchor, which may be actuated to transition between a collapsed delivery state and an expanded deployed state where the anchor centralizes the transducer within the blood vessel. The transducer may be actuated to emit energy to reduce neural activity of the nerves surrounding the blood vessel. Systems and method are further provided for confirming that neural activity of the nerves surround the blood vessel has been sufficiently reduced.

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

The invention provides methods for treating a neurological disorder or deficit, such as tinnitus and phantom limb pain.

The present invention, in some embodiments thereof, relates to a devices and methods for intravascular denervation and assessment thereof and, more particularly, but not exclusively, to devices and methods for renal denervation. Some embodiments of the invention relate to an intravascular catheter configured for ultrasonic ablation of the tissue, comprising a plurality of piezoelectric transceivers. In some embodiments, an intravascular distancing device is provided, the device adapted for obtaining at least a minimal distance between an ultrasound emitting element and a tissue, such as the blood vessel wall. Some embodiments of the invention relate to assessment of renal sympathetic denervation (RSD) treatment effectiveness. Some embodiments of the invention relate to processing echo of signals, such as processing of signals to characterize physical and/or mechanical properties of the blood vessel.

A process for recovering one or more blastocysts from a uterus of a human includes a step of placing a device transvaginally into a cervical canal of the patient; a step of delivering fluid through the device to the uterus and applying a vacuum to a uterus of the patient to aspirate fluid and entrained one or more blastocysts from the uterus; and a step of performing a biopsy procedure on the one or more recovered blastocysts to remove one or more of trophectoderm cells or inner cell mass from the recovered blastocysts. The process may further include a step of storing one or more of the biopsied trophectoderm cells or inner cell mass following the biopsy procedure and a step of performing at least one molecular diagnostic assay test on the one or more of the biopsied trophectoderm cells or inner cell mass.

A facial skin care device and a method of operating the same are disclosed. The facial skin care device comprises an oral insertion module configured to have a structure inserted in an oral cavity and include one or more oral electrodes contacted with a skin in the oral cavity, and a main body configured to include a main electrode connected electrically to at least one of the oral electrode on an outer surface of a facial skin and a current generation unit which is connected to the main electrode and generates current for applying electrical stimulation to the facial skin.