An ultrasound system includes transmit circuitry configured to produce a push pulse electrical excitation signal and a transducer array configured to receive the push pulse electrical excitation signal and transmit a push pulse that produces acoustic and shear wave propagation in tissue of interest, where the push pulse is based on a pre-determined set of parameters stored in computer readable medium. A computer-implemented method includes producing a push pulse electrical excitation signal and includes transmitting, based on the push pulse electrical excitation signal, a push pulse that produces acoustic and shear wave propagation in tissue of interest. A computer readable medium is encoded with computer executable instructions, which, when executed by a processor, cause the processor to perform the method. In one instance, the push pulse promotes shedding of lining cells of the tissue of interest in connection with a biopsy of shed cells for the tissue of interest.

A TUS (transcranial ultrasound) system with a matrix array transducer in a wearable format is disclosed. The TUS system uses ASIC (application-specific integrated circuit) and MEMS (micro-electromechanical system) technologies to achieve power, size, and weight reductions, allowing the device to be worn. In an embodiment, the TUS system can reliably find a target anatomical structure and remain locked onto the target throughout usage. All real-time tasks are controlled locally within the TUS system for a closed-loop operation. Safeguards enable subjects to use the system at home for medical treatment and wellness usage, as well as in a clinic. A method for using the system is disclosed.

Apparatuses and methods to generate high frequency shock waves in a controlled manner. The generated shock waves can be delivered to certain cellular structures of a patient for use in medical and/or aesthetic therapeutic applications. The shock waves can be configured to impose sufficient mechanical stress to the targeted cells of the tissue to rupture the targeted cells. Embodiments of the apparatuses and methods of the present invention provide targeted rupturing of specific cells without damaging side effects such as cavitation or thermal degradation of surrounding non-targeted cells.

A wearable ultrasound apparatus for the diagnosis and treatment of pathological tendon tissue is provided including a flexible transducer array housing comprising a plurality of transducer sub-arrays further comprised of a plurality of piezoelectric transducer elements. Wherein the flexible transducer housing includes at least two or more transducer sub-arrays the placed within adjacent segments, each segment separated by a flexible hinge that allows for contouring of the array to a patient's anatomy. The bottom side of the flexible transducer housing being secured to an acoustic impedance layer and the bottom side of the acoustic impedance layer being secured to an adhesive layer. The adhesive layer holds the flexible transducer housing and the entirety of its contents onto a patient's skin for imaging. The wearable ultrasound diagnosis and therapeutic apparatus is multifunctional with improved real time accuracy in targeting of pathological tendon tissue that is modular, flexible, wearable, and user and patient friendly.

Retinal disease is responsible for many instances of vision impairment. Often, individuals with vision impaired due to retinal disease continue to have functioning retinal neurons. Thus, systems, methods, and devices to stimulate retinal neurons may restore sight for vision-impaired individuals. Systems, methods, and devices provided herein direct ultrasound energy into retinal neurons and modulate phase and amplitude of ultrasound energy in time and space domains in order to variously stimulate various retinal neurons, generating neural responses consistent with visual reproduction of intended images.

Disclosed herein is an ultrasound system and method for cleaning and/or regenerating one or more structures within an oral cavity. The ultrasound system includes a bite guard for insertion and positioning in an oral cavity. The bite guard includes one or more ultrasound transducers for applying a selected ultrasound signal to one or more structures within an oral cavity to clean and/or regenerate the one or more structures within the oral cavity.

Various devices related to a therapeutic ultrasound device for use during a medical procedure to cauterize tissue are disclosed. The high intensity focused ultrasound device can include a transducer for producing high intensity focused ultrasound. The transducer includes a shell configured to receive an acoustic stack. The acoustic stack includes a piezoelectric layer, a matching layer, and a plurality of electrodes. The transducer includes an air-filled pocket formed between the inner surface of the shell and the piezoelectric layer of the acoustic stack, wherein the air-filled pocket is configured to ensure high efficiency of the transducer.