The present invention relates to an implantable device (1) comprising: an ultrasonic unit (11) which includes an electric connection terminal, a support plate (12) which includes a through-opening for the connection terminal to pass through, and an attachment piece (13) which can cooperate with the connection terminal, the attachment piece (13) including a collar for pressing the support plate (12) against the ultrasonic unit (11) when the ultrasonic unit (11), the support plate (12) and the attachment piece (13) are joined.

The present disclosure discloses an array-type ultrasound therapy system. The ultrasound therapy system includes an ultrasound therapy control unit, an ultrasound transducer driving array, and an ultrasound transducer array. The ultrasound transducer array includes n ultrasound transducers; and a detection signal output end of the ultrasound transducer configured to detect ultrasound echoes generated during ultrasound therapy is connected to a feedback signal input end of the ultrasound therapy control unit. A control signal output end of the ultrasound therapy control unit is connected to an input end of the ultrasound transducer driving array, and an output end of the ultrasound transducer driving array is connected to a driving end of each of the ultrasound transducers configured to perform the ultrasound therapy.

Approaches for performing magnetic resonance (MR) imaging of an anatomic region in conjunction with an ultrasound operation on the anatomic region include transmitting multiple ultrasound waves or pulses having a fundamental frequency and multiple harmonics to the anatomic region; transmitting an MR pulse sequence to the anatomic region and receiving, therefrom, MR signals within a band of frequencies; and causing the band of frequencies to be located between two adjacent frequencies of the harmonics.

An ultrasonic radiator includes a plurality of plate-like elements, a supporter, and a first adhesive. The plurality of plate-like elements each have, on the front side or the back side, a radiation surface from which ultrasonic waves are emitted. The supporter holds the plurality of plate-like elements in such a manner that the respective radiation surfaces in different directional orientations are directed toward the same location. The plurality of plate-like elements are bonded to the supporter with the first adhesive. The plurality of plate-like elements each include a plurality of vibratory elements that are variously located in the radiation surface and that generate ultrasonic waves. The first adhesive is applied to lateral surfaces of each of the plurality of plate-like elements.

A method of distributing data to a transducer array of an ultrasonic device, the transducer array including transduction elements arranged in module units, includes generating a data packet using an optical transceiver controlled by a controller, the data packet including activation instructions encoded in a first wavelength, transmitting the data packet from the controller to a target device via a signal in an optical fiber, the target device having a beam divider device, splitting the data signal, using the beam divider device, into a plurality of data streams, where each of the data streams carries the data packet in an identical phase, transmitting the data streams to the module units, and activating the transduction elements based on the received data streams.

Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.

Provided is a flex-PCB catheter device that is configured to be inserted into a body lumen. The flex-PCB catheter comprises an elongate shaft, an expandable assembly, a flexible printed circuit board (flex-PCB) substrate, a plurality of electronic components and a plurality of communication paths. The elongate shaft comprises a proximal end and a distal end. The expandable assembly is configured to transition from a radially compact state to a radially expanded state. The plurality of electronic elements are coupled to the flex-PCB substrate and are configured to receive and/or transmit an electric signal. The plurality of communication paths are positioned on and/or within the flex-PCB substrate. The communication paths selectively couple the plurality of electronic elements to a plurality of electrical contacts configured to electrically connect to an electronic module configured to process the electrical signal. The flex-PCB substrate can have multiple layers, including one or more metallic layers. Acoustic matching elements and conductive traces can be includes in the flex-PCB substrate.

The present disclosure relates to transcranial ultrasound systems, devices, and methods which are used for treatment rather than for imaging or medical diagnosis. In accordance with one aspect, a system for applying ultrasound energy includes at least three ultrasound applicators configured to be secured against a head of a person and configured to apply ultrasound energy to the head of the person when activated, and a controller configured to control activation and deactivation of the at least three ultrasound applicators based on a predetermined treatment sequence.

Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue are described.

Multifunctional ultrasound systems and methods for body section registration and mapping of microbubble dynamics. A system is provided that includes one or more micromachined ultrasonic transducer arrays (MUTAs) configured to capture a high-resolution image of at least a portion of a body section using ultrasound and monitor microbubble activity during ultrasound treatment. The system includes an image registration module configured to spatially register the high-resolution image with a reference image. The system includes electronics configured to control one or more of drive signal amplitude, frequency filtering, multiplexing, and DC bias voltage. The system can be configured to control ultrasound treatment based on the monitoring of the microbubble activity during treatment.