Disclosed is a focused ultrasound operation apparatus that includes: an operation hand piece that includes a handle unit that is used as a handle for a user; a cartridge that includes an ultrasound treatment unit, which generates a focused ultrasound, and has the shape of a circular cylinder or bar, the cartridge being attached to, and detached from, the operation hand piece; a window provided on the cartridge to pass the focused ultrasound generated by the ultrasound treatment unit; and a driver that drives the ultrasound treatment unit to move the ultrasound treatment unit forward and backward.

In embodiments, devices, methods and systems to analyze the different mediums of brain function in a mathematically uniform manner may be provided. These devices, methods and systems may manifest at several levels and ways relating to brain physiology, including neuronal activity, molecular chirality and frequency oscillations. For example, in an embodiment, a computer-implemented method for determining structure of living neural tissue may comprise receiving at least one signal from at least one read modality, the signal representing at least one physical condition of the living neural tissue, determining action potentials based on the signals received from the read modalities, determining frequency oscillations based on the signals received from the read modalities and the action potentials, and determining neuron network structures based on the signals received from the read modalities, the action potentials, and the frequency oscillations.

Embodiments of a dermatological cosmetic treatment and/or imaging system and method can include use of transducer to create a linear thermal treatment zone at a focal depth to form a band shaped treatment area. The system can include one or more ultrasound transducers, a cylindrical transduction element, an imaging element, a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, a coated transducer may be used to provide more consistent treatment in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the dcolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided. Treatment may include heating of tissue for a duration to deactivate a percentage of cells in the treatment region.

A cartridge for a high intensity focused ultrasound (HIFU) device and a piezoelectric linear motor are disclosed. By using the cartridge for a HIFU device according to the present invention, a transducer module is coupled to a piezoelectric linear motor driveable in water and embedded in the cartridge, heat generated when a conventional step motor is driven is fundamentally removed, an additional cooling fan is not needed, ultra-low power consumption and ultra-precise transfer can be realized, and thus an effective procedure can be performed. A skin beauty device may include ultrasound and high frequency units, apply a high frequency to a skin to be treated so as to crack a stratum corneum, and apply ultrasound to the skin to be treated, and thus a medicament drug can easily penetrate the treated skin. In addition, the piezoelectric linear motor in which a piezoelectric actuator and a moving shaft are stably coupled is provided.

The subject matter of the present disclosure generally relates to techniques for following a treatment protocol having one or more treatment parameters to cause a targeted physiological outcome at a distal site, assessing an expression level of a gene in a region of interest after completing the treatment protocol, and modifying the one or more treatment parameters based on the expression level of the gene. The treatment protocol may include one or more ultrasound energy treatments to the region of interest.

A spherical-confocal-split array with dual frequency of fundamental and harmonic superimposition includes: array elements which are spherically confocal, whose quantity is an even number, wherein a half of the array elements operate with a lower frequency, and the other half of the array elements operate with a higher frequency; both the lower frequency and the higher frequency are MHz high-frequencies; each of the array elements corresponds to a frequency drive; array element beams don't superimpose outside the focal region; each of the array elements is connected to a channel amplifier (3) through corresponding impedance matching (2); and a multi-channel waveform controller (4) is connected to the channel amplifier (3) for controlling amplitudes and phases of all channels. The dual-frequency spherical sectorial split array is able to generate split multi-foci of the focal plane with the dual frequencies; and control strong interference of transient cavitation clouds at the adjacent foci.

Arrangements described herein relate to systems, apparatuses, and methods for managing gel on a subject to provide gel on a first area of the subject, including controlling a transducer to move to a second area of the subject and controlling the transducer to move the gel to the first area from the second area.

Disclosed herein are example embodiments of devices, systems, and methods for mechanical fractionation of biological tissue using magnetic resonance imaging (MRI) feedback control. The examples may involve displaying an image representing first MRI data corresponding to biological tissue, and receiving input identifying one or more target regions of the biological tissue to be mechanically fractionated via exposure to first ultrasound waves. The examples may further involve applying the first ultrasound waves and, contemporaneous to or after applying the first ultrasound waves, acquiring second MRI data corresponding to the biological tissue. The examples may also involve determining, based on the second MRI data, one or more second parameters for applying second ultrasound waves to the biological tissue, and applying the second ultrasound waves to the biological tissue according to the one or more second parameters.

Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue on a face and/or neck are described.

Various approaches for disrupting target tissue for treatment include identifying a target volume of the target tissue; causing disruption of the target tissue in a region corresponding to the target volume so as to increase tissue permeability therein; computationally generating a tissue permeability map of the target volume; and based on the tissue permeability map, computationally evaluating the disruption of the target tissue within the target volume.