The invention relates to a drying unit (22) for drying printed substrates (21), comprising a chamber (23) with a gaseous medium which is oxygen-reduced by means of an inert gas, wherein the substrates (21) are guided through the chamber (23) or at least can be guided through the chamber, and the chamber (23) has an entrance for the substrates (21) to be guided into the chamber (23) in the transport direction (T) of the substrates (21). The entrance for the substrates (21) to be guided into the chamber (23) is formed by two cylinders (04; 06) which are positioned against each other longitudinally. The cylinders (04; 06) positioned against each other at the entrance of the chamber (23) form a printing unit (03). One of the cylinders (04) is designed as a printing cylinder (04), and the other cylinder (06) is designed as a cylinder (06) which interacts with the printing cylinder (04) and applies a printed image onto the affected substrates (21). The two cylinders (04; 06) which are positioned against each other under pressure at the entrance of the chamber (23) form a seal which runs axially to the cylinders (04; 06) for preventing the oxygen-reduced gaseous medium from leaking out of the chamber (23) and/or for preventing oxygen from the ambient air from entering the chamber (23). The printing unit (03) arranged at the entrance of the chamber (23) is designed as a printing unit (03) for an intaglio printing process.

A gravure printing unit is provided by which substrate can be printed according to a gravure printing method. The gravure printing unit has a forme cylinder, which comprises, on its circumference, an image-forming pattern of recesses, and has an inking unit by which the pattern of recesses provided on the forme cylinder can be at least partially inked. The forme cylinder can be partially inked from an inking device via a first inking unit cylinder, which has, in the region of its lateral surface, recesses that correspond to recesses on the forme cylinder, and via a second inking unit cylinder, which is to be partially inked by the first inking unit cylinder. To produce an image element to be used for checking a relative position between the forme cylinder and the first inking unit cylinder, the forme cylinder has, within the printing width but preferably outside of an image-forming pattern of recesses that supplies the print image of one or more N-up copies, and lying in a circumferential region, at least one first recess, which overlaps on the forme cylinder only partially with a projection, which is obtained on the forme cylinder by the rolling off, in pairs in each case, of the inking unit cylinders that are involved in the ink transport, of a recess, which is provided in a defined position and location on the circumference of the first inking unit cylinder for the purpose of checking the relative position. A substrate section and a method for checking and/or adjusting and/or correcting a relative position between the first inking unit cylinder and the forme cylinder are also disclosed.

Recess printing units are usable for printing on a substrate and using associated methods for operation. The recess printing units comprise an intaglio printing cylinder, which provides an image-forming pattern of recesses on its circumference; and an inking unit for applying ink to the pattern of recesses that are provided on the intaglio printing cylinder. The inking unit comprises a first inking unit cylinder which has, in a region of its lateral surface, recesses corresponding to the recesses in the intaglio printing cylinder and to which recesses ink can be supplied by an ink application device in the region of an application point lying on the circumference of the first inking unit cylinder. A second inking unit cylinder cooperates with the first inking unit cylinder and has, in a region of the lateral surface of the second inking unit cylinder, elevations corresponding to recesses in the intaglio printing cylinder or raised regions corresponding to regions of the image-forming pattern of recesses on the intaglio printing cylinder, which regions comprise recesses. The ink application device also comprises, on at least a downstream side of the application point, with respect to the operating direction of rotation of the inking unit cylinder comprising the recesses, a retaining device in the form of a doctor blade or an ink knife. The second inking unit cylinder comprises, on a lateral surface thereof, elevations corresponding to engraving on the intaglio printing cylinder.

A gravure printing unit is provided by which substrate can be printed according to a gravure printing method. The gravure printing unit has a forme cylinder, which comprises, on its circumference, an image-forming pattern of recesses, and has an inking unit by which the pattern of recesses provided on the forme cylinder can be at least partially inked. The forme cylinder can be partially inked from an inking device via a first inking unit cylinder, which has, in the region of its lateral surface, recesses that correspond to recesses on the forme cylinder, and via a second inking unit cylinder, which is to be partially inked by the first inking unit cylinder. To produce an image element to be used for checking a relative position between the forme cylinder and the first inking unit cylinder, the forme cylinder has, within the printing width but preferably outside of an image-forming pattern of recesses that supplies the print image of one or more N-up copies, and lying in a circumferential region, at least one first recess, which overlaps on the forme cylinder only partially with a projection, which is obtained on the forme cylinder by the rolling off, in pairs in each case, of the inking unit cylinders that are involved in the ink transport, of a recess, which is provided in a defined position and location on the circumference of the first inking unit cylinder for the purpose of checking the relative position. A substrate section and a method for checking and/or adjusting and/or correcting a relative position between the first inking unit cylinder and the forme cylinder are also disclosed.

The invention relates to a drying unit (22) for drying printed substrates (21), comprising a chamber (23) with a gaseous medium which is oxygen-reduced by means of an inert gas, wherein the substrates (21) are guided through the chamber (23) or at least can be guided through the chamber, and the chamber (23) has an entrance for the substrates (21) to be guided into the chamber (23) in the transport direction (T) of the substrates (21). The entrance for the substrates (21) to be guided into the chamber (23) is formed by two cylinders (04; 06) which are positioned against each other longitudinally. The cylinders (04; 06) positioned against each other at the entrance of the chamber (23) form a printing unit (03). One of the cylinders (04) is designed as a printing cylinder (04), and the other cylinder (06) is designed as a cylinder (06) which interacts with the printing cylinder (04) and applies a printed image onto the affected substrates (21). The two cylinders (04; 06) which are positioned against each other under pressure at the entrance of the chamber (23) form a seal which runs axially to the cylinders (04; 06) for preventing the oxygen-reduced gaseous medium from leaking out of the chamber (23) and/or for preventing oxygen from the ambient air from entering the chamber (23). The printing unit (03) arranged at the entrance of the chamber (23) is designed as a printing unit (03) for an intaglio printing process.

Recess printing units are usable for printing on a substrate and using associated methods for operation. The recess printing units comprise an intaglio printing cylinder, which provides an image-forming pattern of recesses on its circumference; and an inking unit for applying ink to the pattern of recesses that are provided on the intaglio printing cylinder. The inking unit comprises a first inking unit cylinder which has, in a region of its lateral surface, recesses corresponding to the recesses in the intaglio printing cylinder and to which recesses ink can be supplied by an ink application device in the region of an application point lying on the circumference of the first inking unit cylinder. A second inking unit cylinder cooperates with the first inking unit cylinder and has, in a region of the lateral surface of the second inking unit cylinder, elevations corresponding to recesses in the intaglio printing cylinder or raised regions corresponding to regions of the image-forming pattern of recesses on the intaglio printing cylinder, which regions comprise recesses. The ink application device also comprises, on at least a downstream side of the application point, with respect to the operating direction of rotation of the inking unit cylinder comprising the recesses, a retaining device in the form of a doctor blade or an ink knife. The second inking unit cylinder comprises, on a lateral surface thereof, elevations corresponding to engraving on the intaglio printing cylinder.

There is described a sheet-fed printing press (1000; 1000*) comprising at least two printing units (200; 200.1, 200.2; 200.1*, 200.2*) located one after the other, each printing unit (200; 200.1, 200.2; 200.1*, 200.2*) being adapted to carry out simultaneous recto-verso printing of the sheets (S) and including two printing cylinders (105, 106) cooperating with one an other and forming a printing nip, the two printing cylinders (105, 106) each collecting ink patterns from at least two associated plate cylinders (15A, 15B, 16A, 16B) wherein the two printing cylinders (105, 106) are located one above the other such that the sheets (S) travel laterally through each printing unit (200; 200.1, 200.2; 200.1*, 200.2*) from a first lateral side (201 a; 201 a*) located upstream of the printing nip to a second lateral side (201 b; 201 b*) located downstream of the printing nip, wherein a number of at least two sheet transfer elements (110, 120, 95) is provided downstream of the printing nip of a first one (200.1; 200.1*) and upstream of the printing nip of a second one (200.2; 200.2*) of the at least two printing units (200.1, 200.2; 200.1*, 200.2*) to transfer the sheets (S).

The invention provides for the use of pharmaceutical compositions comprising a thiazolide in the stimulation of the immune system in a subject in need thereof, thereby preventing and/or treating viral diseases, cancer and diseases caused by intracellular protozoan infections.

An apparatus and method for use in generating a print job for an offset printing apparatus. The method comprising determining a print job to be printed on the offset printer comprises an odd number of separations, and in response to determining that the print job comprises an odd number of separations, alternating a print order of at least two separations between odd and even pages of the print job.

In some examples, an intaglio gravure printing press includes at least one gravure printing unit having at least one forme cylinder, at least one impression cylinder, at least one inking unit and/or at least one ink collecting cylinder. Additionally, at least one assigned inking unit, at least one print head, and at least one wiping device are arranged at the at least one forme cylinder. The wiping device is arranged along the direction of rotation of the forme cylinder, and downstream from the print head when the print head is arranged at the at least one forme cylinder. In addition, the wiping device is arranged along the direction of rotation of the forme cylinder, upstream from a contact region of the forme cylinder with the impression cylinder. Alternatively, in some examples, at least one print head is arranged at the at least one impression cylinder.