Methodology for encouraging hair growth in male humans, and more particularly to methodology which involves application of electromagnetic radiation, mechanical vibrations, along with applications of combined minoxidil, mint oil, (preferably menthol containing essential peppermint oil), ginger oil, lavender oil, castor bean oil, jojoba oil; melaleuca oil, cumin oil, D-alpha tocopherol (vitamin E) infused oil, biotin infused oil and a single selection, or dry mixture and/or liquid “tea” formed from selections from the group consisting of powdered saw palmetto; powdered horsetail; powdered ginger; powdered stinging nettles; powdered horny goat weed; powdered pueraria lobate; powdered Tribulus terrestris; powdered ashwagandha; powdered capsicum; powdered habenero; powdered green tea; powdered sage; powdered gingko biloba; powdered myrrh; powdered alpha-hydroxy; powdered Aloe vera; powdered wheat protein; powdered wheat starch; powdered casein, powdered keratin, powdered folic acid; powdered fenugreek seed and powdered biotin powdered ginseng Root; powdered vetiver grass; powdered caffeine; powdered Co-enzyme Q; powdered folate; powdered gotukola leaf; powdered milk thistle; powdered African pygeum; powdered stinging nettles; powdered gingko biloba; powdered myrrh; powdered alpha-hydroxy; powdered caffeine; powdered niacinamide (NAD) and/or niacin; and powdered Nigella sativa; powdered Eclipta alba; powdered Centella asiatica; powdered Phyllanthus emblica in water and alcohol, or an oil.

Methodology for encouraging hair growth in male humans, and more particularly to methodology which involves application of electromagnetic radiation, mechanical vibrations, along with applications of combined minoxidil, mint oil, (preferably menthol containing essential peppermint oil), ginger oil, lavender oil, castor bean oil, jojoba oil; melaleuca oil, cumin oil, D-alpha tocopherol (vitamin E) infused oil, biotin infused oil and a single selection, or dry mixture and/or liquid “tea” formed from selections from the group consisting of powdered saw palmetto; powdered horsetail; powdered ginger; powdered stinging nettles; powdered horny goat weed; powdered pueraria lobate; powdered Tribulus terrestris; powdered ashwagandha; powdered capsicum; powdered habenero; powdered green tea; powdered sage; powdered gingko biloba; powdered myrrh; powdered alpha-hydroxy; powdered Aloe vera; powdered wheat protein; powdered wheat starch; powdered casein, powdered keratin, powdered folic acid; powdered fenugreek seed and powdered biotin powdered ginseng Root; powdered vetiver grass; powdered caffeine; powdered Co-enzyme Q; powdered folate; powdered gotukola leaf; powdered milk thistle; powdered African pygeum; powdered stinging nettles; powdered gingko biloba; powdered myrrh; powdered alpha-hydroxy; powdered caffeine; powdered niacinamide (NAD) and/or niacin; and powdered Nigella sativa; powdered Eclipta alba; powdered Centella asiatica; powdered Phyllanthus emblica in water and alcohol, or an oil.

The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

The present disclosure relates to a composition for treating or preventing alopecia including decursin, wherein when administered externally or orally, the decursin promotes secretion of KGF in hair follicle tissues, prevents apoptosis of hair follicle cells, and exhibits the effect of promoting hair growth, thereby being useful for the treatment or prevention of alopecia.

The present disclosure relates to a composition for treating or preventing alopecia including decursin, wherein when administered externally or orally, the decursin promotes secretion of KGF in hair follicle tissues, prevents apoptosis of hair follicle cells, and exhibits the effect of promoting hair growth, thereby being useful for the treatment or prevention of alopecia.

There is provided a formulation for skin rejuvenation comprising lyophilised umbilical cord plasma comprising at least one active chemokine, at least one growth factor and at least one cytokine; a transdermal carrier; and a liposomal base, wherein at least a portion of the lyophilised umbilical cord plasma and transdermal carrier are contained within liposomes of the liposomal base. There is also provided a dosage form for skin rejuvenation comprising 1-5% (w/w) lyophilised umbilical cord plasma comprising at least one active chemokine, at least one growth factor and at least one cytokine; 85-95% (w/w) polyethylene glycol; and 0.1-2% (w/w) gum acacia.

The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

Proteins that bind IL-1α and IL-1β are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-1-related disorders and for detecting IL-1α and IL-1β in cells, tissues, samples, and compositions.

Present invention discloses particular peptide sequences of formula (I);

(R.sup.1).sub.(m)-Xaa.sub.1IXaa.sub.2T(Q).sub.(p)(R.sup.2).sub.(n)   (I) (SEQ ID NO: 1);

wherein R.sup.1, m, p, n, Xaa.sub.1, Xaa.sub.2, and R.sup.2 have particular meanings, or pharmaceutically or veterinary acceptable salts of these peptides that are effective in the prevention and/or treatment of mammal hair loss.

Invention also relates to particular topical pharmaceutical, nutraceutical or veterinary compositions with the peptides of formula (I).

Present invention discloses particular peptide sequences of formula (I);

(R.sup.1).sub.(m)-Xaa.sub.1IXaa.sub.2T(Q).sub.(p)(R.sup.2).sub.(n)   (I) (SEQ ID NO: 1);

wherein R.sup.1, m, p, n, Xaa.sub.1, Xaa.sub.2, and R.sup.2 have particular meanings, or pharmaceutically or veterinary acceptable salts of these peptides that are effective in the prevention and/or treatment of mammal hair loss.

Invention also relates to particular topical pharmaceutical, nutraceutical or veterinary compositions with the peptides of formula (I).